ST714-SCCmec type IV CA-MRSA isolated from a Child with Recurrent Skin and Soft Tissue Infections in South Korea: A Case Report
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Skin and soft tissue infections (SSTIs) caused by community-associated (CA)-methicillin-resistant Staphylococcus aureus (MRSA) have become a worldwide concern. An otherwise healthy 16-month-old Korean girl was admitted because of skin abscess on the left chest wall with a history of recurrent SSTIs since the age of 6 months. Immunologic evaluation including serum immunoglobulin level and nitroblue-tetrazolium (NBT) test were normal. Pus and nasal swab cultures revealed CA-MRSA ST714-SCCmec type IV with the Panton-Valentine leukocidin (PVL) genes, which was initially reported in the Netherlands in 2006 and has not been previously reported in Korea. The skin abscesses were successfully treated by needle aspiration and the use of antibiotics. In addition, nasal mupirocin was applied as a decolonization method. No more episodes of SSTI were observed over a follow-up period of 10 months.
Abstract
Skin and soft tissue infections (SSTIs) caused by community-associated (CA)-methicillin-resistant Staphylococcus aureus (MRSA) have become a worldwide concern. An otherwise healthy 16-month-old Korean girl was admitted because of skin abscess on the left chest wall with a history of recurrent SSTIs since the age of 6 months. Immunologic evaluation including serum immunoglobulin level and nitroblue-tetrazolium (NBT) test were normal. Pus and nasal swab cultures revealed CA-MRSA ST714-SCCmec type IV with the Panton-Valentine leukocidin (PVL) genes, which was initially reported in the Netherlands in 2006 and has not been previously reported in Korea. The skin abscesses were successfully treated by needle aspiration and the use of antibiotics. In addition, nasal mupirocin was applied as a decolonization method. No more episodes of SSTI were observed over a follow-up period of 10 months.
참고문헌 (12)
- Lee J, "Molecular characterization of methicillin-resistant Staphylococcus aureus obtained from the anterior nares of healthy Korean children attending daycare centers", Int J Infect Dis, 15, pp.e558~e563 (2011)
- Sung JY, "Changes in molecular epidemiology of community-associated and health careassociated methicillin-resistant Staphylococcus aureus in Korean children", Diagn Microbiol Infect Dis, 74, pp.28~33 (2012)
- Enright MC, "The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)", Proc Natl Acad Sci U S A, 99, pp.7687~7692 (2002)
- McDougal LK, "Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database", J Clin Microbiol, 41, pp.5113~5120 (2003)
- Moran GJ, "Methicillin-resistant S. aureus infections among patients in the emergency department", N Engl J Med, 355, pp.666~674 (2006)
- David MZ, "Community-associated methicillinresistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic", Clin Microbiol Rev, 23, pp.616~687 (2010)
- Croes S, "Unpredictable effects of rifampin as an adjunctive agent in elimination of rifampin-susceptible and -resistant Staphylococcus aureus strains grown in biofilms", Antimicrob Agents Chemother, 54, pp.3907~3912 (2010)
- Croes S, "Staphylococcus aureus biofilm formation at the physiologic glucose concentration depends on the S. aureus lineage", BMC Microbiol, 9, pp.229~ (2009)
- 고재훈, "First Imported Case of Skin Infection Caused by PVL-positive ST30 Community-Associated Methicillin-Resistant Staphylococcus aureus Clone in a Returning Korean Traveler from the Philippines", Journal of Korean Medical Science, 28(7), pp.1100~1102 (2013), 대한의학회
- 최영준, "소아 황색포도알균 감염증의 임상양상에 대한 고찰: 지역사회 관련 메티실린 내성 황색포도알균 감염을 중심으로", Pediatric Infection and Vaccine, 16(2), pp.150~161 (2009), 대한소아감염학회
- Chen AE, "Discordance between Staphylococcus aureus nasal colonization and skin infections in children", Pediatr Infect Dis J, 28, pp.244~246 (2009)
- Fritz SA, "Household versus individual approaches to eradication of community-associated Staphylococcus aureus in children: a randomized trial", Clin Infect Dis, 54, pp.743~751 (2012)