폐구균에 의한 괴사성 폐렴 후 합병한 비전형적 용혈성 요독 증후군 1례
A Case of Hemolytic Uremic Syndrome Complicated by Pneumococcal Necrotizing Pneumonia
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Streptococcus pneumoniae is a common cause of acute otitis media, sinusitis, pneumonia, and the invasive bacterial infections in children. Rarely, S. pneumoniae is an uncommon cause of hemolytic-uremic syndrome (HUS). We report a 33 month-old girl who presented with pneumonia, and subsequently developed HUS. Her pulmonary infection was complicated by necrotizing pneumonia and acute respiratory distress syndrome. Cultures from blood and pleural fluid grew S. pneumoniae, serotype 19A. She was treated with antibiotics, dialysis and mechanical ventilatory support. She was discharged with normal renal function after 2 months of management. She remained healthy without renal complications at the 5 year follow-up visit. (Korean J Pediatr Infect Dis 2008;15:206-211)
Abstract
Streptococcus pneumoniae is a common cause of acute otitis media, sinusitis, pneumonia, and the invasive bacterial infections in children. Rarely, S. pneumoniae is an uncommon cause of hemolytic-uremic syndrome (HUS). We report a 33 month-old girl who presented with pneumonia, and subsequently developed HUS. Her pulmonary infection was complicated by necrotizing pneumonia and acute respiratory distress syndrome. Cultures from blood and pleural fluid grew S. pneumoniae, serotype 19A. She was treated with antibiotics, dialysis and mechanical ventilatory support. She was discharged with normal renal function after 2 months of management. She remained healthy without renal complications at the 5 year follow-up visit. (Korean J Pediatr Infect Dis 2008;15:206-211)
참고문헌 (22)
- Kliegman RM, "Nelson Textbook of Pediatrics", pp.1130~1135 (2007), WB Saunders co
- Waters AM, "Fitzpatric MM, Gilbert RD, et al. Hemolytic uremic syndrome associated with invasive pneumococcal disease:the United Kingdom experience", J Pediatr, 151, pp.140~144 (2007)
- Geary DF, "Hemolytic uremic syndrome and Streptococcus pneumoniae: improving our understanding", J Pediatr, 151, pp.113~1134 (2007)
- Cabrera GR, "Cooperstone BG. Hemolytic uremic syndrome associated with invasive Streptococcus pneumoniae infection", Pediatrics, 101, pp.699~703 (1998)
- Constantinescu AR, "Non-enteropathic hemolytic uremic syndrome: causes and short-term course", Am J Kidney Dis, 43, pp.976~982 (2004)
- Brandt J, "Invasive pneumococcal disease and hemolytic uremic syndrome", Pediatrics, 110, pp.371~376 (2002)
- Vanderkooi OG, "Invasive Streptococcus pneumoniae infection causing hemolytic uremic syndrome in children: Two recent cases", Can J Infect Dis, 14, pp.339~343 (2003)
- Jo HS, "Two cases of hemolytic uremic syndrome associated with pneumococcal infection", J Korean Soc Pediatr Nephrol, 2, pp.227~231 (1999)
- Hwang SJ, "A case of atypical hemolytic uremic syndrome associated with invasive Streptococcus pneumoniae infection", J Korean Soc Pediatr Nephrol, 1, pp.104~108 (1999)
- Sim YH, "A case of hemolytic uremic syndrome induced by pneumococcal infection", J Korean Soc Pediatr Nephrol, 10, pp.237~242 (2002)
- Lee HS, "Atypical hemolytic uremic syndrome associated with Streptococcus pneumoniae infection", Korean J Pediatr, 47, pp.217~222 (2004)
- Kim E, "Multiple extrarenal manifestations in hemolytic uremic syndrome", Korean J Pediatr, 50, pp.1261~1265 (2007)
- Klein PJ, "Thomsen-Friedenreich antigen in haemolytic-uraemic syndrome", Lancet, 2, pp.1024~1025 (1977)
- Hsieh YC, "Necrotizing pneumococcal pneumonia in children: the role of pulmonary gangrene", Pediatr Pulmonol, 41, pp.623~629 (2006)
- Bender JM, "Pneumococcal necrotizing pneumonia in Utah: does serotype matter?", Clin Infect Dis, 46, pp.1346~1352 (2008)
- McCarthy VP, "Necrotizing Pneumococcal Pneumonia in Childhood", Pediatr Pulmonol, 28, pp.217~221 (1999)
- Whitney CG, "Lynfield R, et al. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine", N Engl J Med, 348, pp.1737~1746 (2003)
- Lee JA, "Serotypes and Penicillin Susceptibility of Streptococcus pneumoniae Isolated from Clinical Specimens and Healthy Carriers of Korean Children", J Korean Pediatr Soc, 46, pp.846~853 (2003)
- Song EK, "Epidemiology and Clinical Features of Invasive Pneumococcal Infections in Children", Korean J Pediatr Infect Dis, 12, pp.140~148 (2005)
- Kim SH, "Changes of serotype distribution of Streptococcus pneumoniae isolated from children in Korea over a 15 year-period (1991-2005)", Korean J Pediatr Infect Dis, 13, pp.89~98 (2006)
- Pai R, "Postvaccine genetic structure of Streptococcus pneumoniae serotype 19A from children in the United States", J Infect Dis, 192, pp.1988~1995 (2005)
- Choi EH, "Streptococcus pneumoniae serotype 19A in Children, South Korea", Emerg Infect Dis, 14, pp.275~281 (2008)