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Intravenous Immunoglobulin Nonresponsive Symptomatic Myocarditis during the Acute Stage of Incomplete Kawasaki Disease

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초록

We report the case of a 7-year-old boy who showed treatment-nonresponsive hypotension (59/29 mmHg) and decreased left ventricular systolic function (fractional shortening 22%) in the acute stage of Kawasaki disease (KD). The present case serves to highlight that methylprednisolone pulse therapy should be considered in patients with intravenous immunoglobulin nonresponsive symptomatic myocarditis during the acute stage of KD.

Abstract

We report the case of a 7-year-old boy who showed treatment-nonresponsive hypotension (59/29 mmHg) and decreased left ventricular systolic function (fractional shortening 22%) in the acute stage of Kawasaki disease (KD). The present case serves to highlight that methylprednisolone pulse therapy should be considered in patients with intravenous immunoglobulin nonresponsive symptomatic myocarditis during the acute stage of KD.

참고문헌 (11)

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  7. Schultheiss HP, "The management of myocarditis", Eur Heart J, 32, pp.2616~2625 (2011)
  8. Rosenfeld EA, "Comparative safety and efficacy of two immune globulin products in Kawasaki disease", J Pediatr, 26, pp.1000~1003 (1995)
  9. Singh S, "Late symptomatic myocarditis in Kawasaki disease: an unusual manifestation", Indian J Pediatr, 81, pp.404~405 (2014)
  10. Saneeymehri S, "Overview of pharmacological treatment options for pediatric patients with refractory kawasaki disease", J Pediatr Pharmacol Ther, 20, pp.163~177 (2015)
  11. Fan PC, "School-aged children with Kawasaki disease: high incidence of cervical lymphadenopathy and coronary artery involvement", J Paediatr Child Health, 39, pp.55~57 (2003)

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