Electric Conduction Effects in the Neuronal Cytoskeleton Hold the Key to Our Understanding of the Biophysics of Consciousness
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Electrical activity of the brain is the basis of our understanding of neurophysiology. Electrical signals in the form of action potentials propagate along axons and are relayed via synaptic connections between neurons. Neuronal cytoskeleton is constructed from parallel bundles of microtubules interconnected by microtubule associated proteins (MAPs). In this paper we provide an overview of the electrical properties of microtubules and actin filaments which act as bioelectric circuits. It is well known that impairment of neuronal cytoskeleton results in various neurodegenerative diseases. Therefore, it stands to reason that these electrical properties of neuronal cytoskeleton are of critical importance to our understanding of consciousness as an emergent property. This short paper provides an overview of this issue.
Abstract
Electrical activity of the brain is the basis of our understanding of neurophysiology. Electrical signals in the form of action potentials propagate along axons and are relayed via synaptic connections between neurons. Neuronal cytoskeleton is constructed from parallel bundles of microtubules interconnected by microtubule associated proteins (MAPs). In this paper we provide an overview of the electrical properties of microtubules and actin filaments which act as bioelectric circuits. It is well known that impairment of neuronal cytoskeleton results in various neurodegenerative diseases. Therefore, it stands to reason that these electrical properties of neuronal cytoskeleton are of critical importance to our understanding of consciousness as an emergent property. This short paper provides an overview of this issue.
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