Delayed diagnosis of intramedullary spinal cord germinoma
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Germ-cell tumors (GCTs) are common in the central nervous system. GCTs are highly sensitive to radiotherapy and chemotherapy and can be cured without radical surgery. However, this tumor produces nonspecific imaging findings, and its rarity can make diagnosis challenging. Here we report a case in which the first diagnosis was uncertain and follow-up imaging revealed intramedullary germinoma. The patient underwent chemotherapy and radiotherapy after the diagnosis.
Abstract
Germ-cell tumors (GCTs) are common in the central nervous system. GCTs are highly sensitive to radiotherapy and chemotherapy and can be cured without radical surgery. However, this tumor produces nonspecific imaging findings, and its rarity can make diagnosis challenging. Here we report a case in which the first diagnosis was uncertain and follow-up imaging revealed intramedullary germinoma. The patient underwent chemotherapy and radiotherapy after the diagnosis.
참고문헌 (5)
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- Loya JJ, "Primary spinal germ cell tumors : a case analysis and review of treatment paradigms", Case Rep Med, 2013, pp.798358~ (2013)
- Madhukar M, "Primary intramedullary spinal cord germinoma", J Neurosurg Pediatr, 11, pp.605~609 (2013)
- Aoyama T, "Intramedullary spinal cord germinoma--2 case reports", Surg Neurol, 67, pp.177~183 (2007)
- Joo JH, "Treatment outcome of radiation therapy for intracranial germinoma : adaptive radiation field in relation to response to chemotherapy", Anticancer Res, 34, pp.5715~5721 (2014)
