수술 후 방사선 단독 치료를 시행한 원발성 척수 종자세포종 1예
A Rare Case of Primary Spinal Cord Germinoma Treated with Single Radiation Therapy after Surgery
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A 32-year old male came to our hospital with chief complaint of paraplegia. He had symptom of radiating pain to right leg 3 months ago before paraplegic symptom appeared. Magnetic resonance (MR) imaging from outside hospital showed intramedullary mass involving from T8 to T10 level of spinal cord. According to the imaging result, tumor removal with total laminectomy was performed between T8 and T10 level in our hospital. Pathologic result was compatible with germinoma. Spine radiation (39.6 Gy/22 fx) from T7 to T12 level without chemotherapy was performed 3 weeks later since tumor removal. Follow-up MR imaging showed no recurrence without any distant metastasis. And our patient’s neurologic symptom had been improved. According to this case, postoperative radiotherapy is thought to be effective to primary spinal germinoma.
Abstract
A 32-year old male came to our hospital with chief complaint of paraplegia. He had symptom of radiating pain to right leg 3 months ago before paraplegic symptom appeared. Magnetic resonance (MR) imaging from outside hospital showed intramedullary mass involving from T8 to T10 level of spinal cord. According to the imaging result, tumor removal with total laminectomy was performed between T8 and T10 level in our hospital. Pathologic result was compatible with germinoma. Spine radiation (39.6 Gy/22 fx) from T7 to T12 level without chemotherapy was performed 3 weeks later since tumor removal. Follow-up MR imaging showed no recurrence without any distant metastasis. And our patient’s neurologic symptom had been improved. According to this case, postoperative radiotherapy is thought to be effective to primary spinal germinoma.
참고문헌 (10)
- Nikitovic M, "Intramedullary spinal cord germinoma: a case report and review of literature", World Neurosurg, 95, pp.392~398 (2016)[DOI]
- Wu L, "Treatment strategies and long-term outcomes for primary intramedullary spinal germinomas: an institutional experience", J Neurooncol, 121, pp.541~548 (2015)[DOI]
- Ganslandt O, "Primary spinal germinoma in a patient with concomitant Klinefelter's syndrome", Br J Neurosurg, 14, pp.252~255 (2000)[DOI]
- Nakata Y, "Two patients with intraspinal germinoma associated with Klinefelter syndrome: case report and review of the literature", AJNR Am J Neuroradiol, 27, pp.1204~1210 (2006)
- Tubbs RS, "Isolated intraspinal germinoma in a child with congenital adrenal hyperplasia", Spinal Cord, 46, pp.707~708 (2008)[DOI]
- Yamagata T, "Primary intramedullary spinal cord germinoma: diagnostic challenge and treatment strategy", Neurol Med Chir (Tokyo), 49, pp.128~133 (2009)[DOI]
- Kamoshima Y, "Update on current standard treatments in central nervous system germ cell tumors", Curr Opin Neurol, 23, pp.571~575 (2010)[DOI]
- Rosenblum MK, "The 2007 WHO classification of nervous system tumors: newly recognized members of the mixed glioneuronal group", Brain Pathol, 17, pp.308~313 (2007)[DOI]
- Biswas A, "Spinal intradural primary germ cell tumour--review of literature and case report", Acta Neurochir (Wien), 151, pp.277~284 (2009)[DOI]
- Dearnaley DP, "Pineal and CNS germ cell tumors: Royal Marsden Hospital experience 1962-1987", Int J Radiat Oncol Biol Phys, 18, pp.773~781 (1990)[DOI]