Autonomic instability in severe tetanus: a case report
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Tetanus is an infectious disease of the nervous system caused by Clostridium tetani, and is characterized by tonic muscle contractions, painful spasms, and autonomic dysfunction. Severe autonomic dysfunction associated with tetanus can be life-threatening. We present a 62-year-old female who experienced lockjaw after an ankle fracture. The patient was diagnosed with tetanus and received tetanus immunoglobulin and a vaccination. The patient subsequently experienced labile hypertension. This case highlights the challenge and importance of managing cardiovascular instability.
Abstract
Tetanus is an infectious disease of the nervous system caused by Clostridium tetani, and is characterized by tonic muscle contractions, painful spasms, and autonomic dysfunction. Severe autonomic dysfunction associated with tetanus can be life-threatening. We present a 62-year-old female who experienced lockjaw after an ankle fracture. The patient was diagnosed with tetanus and received tetanus immunoglobulin and a vaccination. The patient subsequently experienced labile hypertension. This case highlights the challenge and importance of managing cardiovascular instability.
참고문헌 (10)
- Berkowitz AL, "Tetanus, botulism, and diphtheria", Continuum(Minneap Minn), 24, pp.1459~1488 (2018)
- Wasay M, "Autonomic nervous system dysfunction predicts poor prognosis in patients with mild to moderate tetanus", BMC Neurol, 5, pp.2~ (2005)
- Anuradha S, "Tetanus in adults--a continuing problem: an analysis of 217 patients over 3 years from Delhi, India, with special emphasis on predictors of mortality", Med J Malaysia, 61, pp.7~14 (2006)
- "Infectious disease portal report" (2021)[URL]
- Abrutyn E, "Harrison’s principle’s of internal medicine", pp.898~900 (2008), Mc Graw Hill Inc
- Spruyt GM, "The treatment of autonomic dysfunction in tetanus", South Afr J Crit Care, 33, pp.28~31 (2017)
- Farrar JJ, "Tetanus", J Neurol Neurosurg Psychiatry, 69, pp.292~301 (2000)
- Rodrigo C, "Pharmacological management of tetanus : an evidence-based review", Crit Care, 18, pp.217~ (2014)
- Dundee JW, "Labetalol in severe tetanus", Br Med J, 1, pp.1121~1122 (1979)
- Wesley AG, "Labetalol in tetanus. The treatment of sympathetic nervous system overactivity", Anaesthesia, 38, pp.243~249 (1983)
