Mills증후군 1예
A Case of Mills’ Syndrome
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초록
Mills’ syndrome is rare clinical syndrome described in 1900 by Mills, namely ascending (or less often, descending) progressive hemiplegia. Mills’ syndrome could be considered as a variant of primary lateral sclerosis (PLS) or amyotrophic lateral sclerosis (ALS), but is still controversial. According to clinical course, imaging and electrophysiological findings, our case is more compatible with Mills’ syndrome rather than PLS or ALS. To our knowledge, this is the first report of Mills’ syndrome in Korea.
Abstract
Mills’ syndrome is rare clinical syndrome described in 1900 by Mills, namely ascending (or less often, descending) progressive hemiplegia. Mills’ syndrome could be considered as a variant of primary lateral sclerosis (PLS) or amyotrophic lateral sclerosis (ALS), but is still controversial. According to clinical course, imaging and electrophysiological findings, our case is more compatible with Mills’ syndrome rather than PLS or ALS. To our knowledge, this is the first report of Mills’ syndrome in Korea.
참고문헌 (8)
- Mills CK, "A case of unilateral progressive ascending paralysisprobably representing a new form of degenerative disease", J Nerv Ment Dis, 27, pp.195~200 (1900)
- Gastaut JL, "Mills’ syndrome; ascending (ordescending) progressive hemiplegia: a hemiplegic form ofprimary lateral sclerosis?", J Neurol Neurosurg Psychiatry, 57, pp.1280~1281 (1994)
- Mills CK, "Unilateral ascending paralysis and unilateral descendingparalysis", JAMA, 47, pp.1638~1645 (1906)
- Mills CK, "A case of progressively developinghemiplegia later becoming triplegia resulting from primarydegeneration of the pyramidal tract", J Nerv Ment Dis, 30, pp.385~397 (1903)
- Pringle CE, "Primary lateral sclerosis. Clinical features, neuropathology,and diagnostic criteria", Brain, 115, pp.495~520 (1992)
- Malin JP, "Clinical variants ofamyotrophic lateral sclerosis: hemiplegic type of ALS andMills syndrome. A critical review", Fortschr Neurol Psychiatr, 54, pp.101~105 (1986)
- Forestier NL, "Does primarylateral sclerosis exist?", Brain, 124, pp.1989~1999 (2001)
- Rajabally Y., "Hemiplegic ALS: Millssyndrome", Neurology, 64, pp.1984~1985 (2005)