본문 바로가기
KERD
논문KCI 등재

Uncommon coexistence of myasthenia gravis and amyotrophic lateral sclerosis

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류신경과학

초록

Myasthenia gravis (MG) and amyotrophic lateral sclerosis (ALS) are distinct disorders. ALS affects motor neurons that control muscle movement, while MG controls communication between neurons and muscles, which occurs at neuromuscular junctions. However, on rare occasions, ALS develops after MG and vice versa. The coexistence of the two diseases represents a diagnostic challenge and requires thoughtful interpretation of clinical features. We present the case of a 53-year-old Korean male who developed ALS after MG, confirmed by clinical and electrophysiological follow-up.

Abstract

Myasthenia gravis (MG) and amyotrophic lateral sclerosis (ALS) are distinct disorders. ALS affects motor neurons that control muscle movement, while MG controls communication between neurons and muscles, which occurs at neuromuscular junctions. However, on rare occasions, ALS develops after MG and vice versa. The coexistence of the two diseases represents a diagnostic challenge and requires thoughtful interpretation of clinical features. We present the case of a 53-year-old Korean male who developed ALS after MG, confirmed by clinical and electrophysiological follow-up.

참고문헌 (10)

  1. 박수연, "Incidence and Prevalence of Myasthenia Gravis in Korea: A Population-Based Study Using the National Health Insurance Claims Database", Journal of Clinical Neurology, 12(3), pp.340~344 (2016), 대한신경과학회[DOI]
  2. Jun KY, "Epidemiology of ALS in Korea using nationwide big data", J Neurol Neurosurg Psychiatry, 90, pp.395~403 (2019)
  3. del Mar Amador M, "Unusual association of amyotrophic lateral sclerosis and myasthenia gravis: a dysregulation of the adaptive immune system?", Neuromuscul Disord, 26, pp.342~346 (2016)
  4. Tai H, "Amyotrophic lateral sclerosis and myasthenia gravis overlap syndrome: a review of two cases and the associated literature", Front neurol, 8, pp.218~ (2017)
  5. Yamashita S, "Coexistence of amyotrophic lateral sclerosis and myasthenia gravis", J Neuromuscul Dis, 1, pp.111~115 (2014)
  6. Turner MR, "Autoimmune disease preceding amyotrophic lateral sclerosis: an epidemiologic study", Neurology, 81, pp.1222~1225 (2013)
  7. Ludolph A, "A revision of the El Escorial criteria-2015", Amyotroph Lateral Scler Frontotemporal Degener, 16, pp.291~292 (2015)
  8. Gilhus NE, "Myasthenia gravis: subgroup classification and therapeutic strategies", Lancet Neurol, 14, pp.1023~1036 (2015)
  9. Ohta K, "MuSK antibodies in AChR Ab-seropositive MG vs AChR Ab-seronegative MG", Neurology, 62, pp.2132~2133 (2004)
  10. Rivner MH, "Agrin and low-density lipoprotein–related receptor protein 4 antibodies in amyotrophic lateral sclerosis patients", Muscle nerve, 55, pp.430~432 (2017)

관련 논문AI추천

이 간행물의 다른 논문 (9건)