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Circadian Rhythms in Voiding Function and Dysfunction

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초록

While circadian rhythms in fluid intake, urine production, and urine storage have been substantiated in diurnal human and nocturnal rodents, the mechanism(s) underlying it is largely unknown. With the elucidations of molecular clockwork and its functional significance in mammals, new opportunities arise to investigate possible circadian control of voiding function and dysfunction, which undoubtedly needs immediate attentions of researchers in the field.

Abstract

While circadian rhythms in fluid intake, urine production, and urine storage have been substantiated in diurnal human and nocturnal rodents, the mechanism(s) underlying it is largely unknown. With the elucidations of molecular clockwork and its functional significance in mammals, new opportunities arise to investigate possible circadian control of voiding function and dysfunction, which undoubtedly needs immediate attentions of researchers in the field.

참고문헌 (12)

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  10. van Esseveldt KE, "The suprachiasmatic nucleus and the circadian time-keeping system revisited", Brain Res Brain Res Rev, 33, pp.34~77 (2000)
  11. 김성은, "Transplantation of human adipose-derived stem cells into the urethra ameliorates stress urinary incontinence and blunts the induction of c-Fos immunoreactivities in brain areas related to micturition in female rats", Animal Cells and Systems, 14(4), pp.237~244 (2010), 한국통합생물학회
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