점안용 우황약침액의 안점막자극실험
Eye Irritation Test of Bovis Calculus pharmacopuncture Solutions for Eye Drop
2
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
Objective This study was done to investigate the safety of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration (2005. 10. 21, KFDA 2005-60). After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results 1. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn’t physical problem at 9 rabbits. 2. After Bovis Calculus pharmacopuncture solutionwas medicated in the left eye of the rabbits, there wasn’t eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions I suggested that Bovis Calculus pharmacopuncture solution didn’t induced eye irritation in rabbits.
Abstract
Objective This study was done to investigate the safety of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration (2005. 10. 21, KFDA 2005-60). After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results 1. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn’t physical problem at 9 rabbits. 2. After Bovis Calculus pharmacopuncture solutionwas medicated in the left eye of the rabbits, there wasn’t eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions I suggested that Bovis Calculus pharmacopuncture solution didn’t induced eye irritation in rabbits.
참고문헌 (6)
- 약제학분과회, "제제학", pp.127~432 (2000), 한림원
- 최규동, "黃連, 진피, 秦皮散이 녹농균성 각막염에 미치는 효과에 관한 실험적 연구", 대한외관과학회지, 12(1), pp.18~35 (1999)
- 이상준, "Soft Contact Lens사용 중 발생된녹농균성 각막염 3예", 대한안과학회지, 31(5), pp.681~686 (1990)
- 이상인, "한약임상응용", pp.477~478 (1982), 성보사
- 식품의약품안전청, "의약품 등의 독성시험기준", ~ (2005)
- 서형식, "안병의 외치법에 대한 문헌적 고찰", 한방안이비인후피부과학회지, 10(1), pp.185~208 (1997)