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점안용 소염약침액의 안점막자극실험

Eye Irritation Test of Soyeom pharmacouncture Solution for Eye Drop

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초록

Objectives This study was done to investigate the safety of Soyeompharmacopuncture solution manufactured with freezingdryness method to use eye drop. Methods The eye irritation test of this material was performed according to the Regulation of Korea Food & DrugAdministration(2005. 10. 21, KFDA 2005-60). After Soyeom pharmacopuncture solution was medicated in the left eyeof the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results 1. After Soyeompharmacopuncture solution was medicated in the left eye of the rabbits, there wasnt physical problemat 9 rabbits . 2. After Soyeompharmacopuncture solution was medicated in the left eye of the rabbits, there wasnt eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day.Conclusions I suggested that Soyeompharmacopuncture solution didn't induced eye irritation in rabbits.

Abstract

Objectives This study was done to investigate the safety of Soyeompharmacopuncture solution manufactured with freezingdryness method to use eye drop. Methods The eye irritation test of this material was performed according to the Regulation of Korea Food & DrugAdministration(2005. 10. 21, KFDA 2005-60). After Soyeom pharmacopuncture solution was medicated in the left eyeof the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results 1. After Soyeompharmacopuncture solution was medicated in the left eye of the rabbits, there wasnt physical problemat 9 rabbits . 2. After Soyeompharmacopuncture solution was medicated in the left eye of the rabbits, there wasnt eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day.Conclusions I suggested that Soyeompharmacopuncture solution didn't induced eye irritation in rabbits.

참고문헌 (9)

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  2. 최규동, "黃連, 진피, 秦皮散이 녹농균성 각막염에 미치는 효과에 관한 실험적 연구", 대한외관과학회지, 12(1), pp.18~35 (1999)
  3. 이상준, "Soft Contact Lens 사용 중 발생된녹농균성 각막염 3예", 대한안과학회지, 31(5), pp.681~686 (1990)
  4. 식품의약품안전청, "의약품 등의 독성시험기준", ~ (2005)
  5. 서형식, "외치법에 대한 문헌고찰. 한방안이비인후피부과학회지", 10(1), pp.185~208 (1997)
  6. 서형식, "소염 약침액이 Staphylococcus aureus와 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구", 대한약침학회지, 9(2), pp.73~77 (2006), 대한약침학회
  7. 서형식, "소염 약침액, 황련해독탕, 황련이 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구", 한방안이비인후피부과학회지, 19(2), pp.19~25 (2006), 대한한방안이비인후피부과학회
  8. 서형식, "소염 약침액, 황련해독탕, 황련이 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구", 한방안이비인후피부과학회지, 19(2), pp.19~25 (2006), 대한한방안이비인후피부과학회
  9. 윤미영, "소염약침의 LPS로 유도된 RAW 264.7세포의 염증성 사이토카인 발현에 미치는 영향", 대한약침학회지, 10(3), pp.21~28 (2007), 대한약침학회

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