開鬱種玉湯이 생쥐에 束縛 Stress 負荷後 血中 Hormone 含量과 免疫能 變化에 미치는 影響
Effects of Kaewooljongoktang on Serum Levels of Hormone and Immune Response after Immobilization Stress in Mice
0
조회
0
다운로드
1
인용
0
참고문헌
초록
Abstract
The purpose of this research was to investigate the effects of Kaewooljongoktang water extract (KJT) on immobilization stress in C57BL/6J mice. KJT decreased the serum level of histamine and corticosterone increased by immobilization stress. In addition, KJT enhanced the cell viability of thymocytes and splenocytes decreased by immobilization stress. Also, KJT increased the viability of thymocytes and did not affect the viability of splenocytes in vitro. KJT did not affect DNA fragmentation of thymocytes and decreased DNA fragmentation of splenocytes increased by immobilization stress. KJT did not affect the population of thymic CD4+ cells increased by immobilization stress, and increased the population of B220+ cells decreased by immobilization stress and increased the population of splenic CD4+ cells increased by immobilization stress. KJT enhanced the production of -interferon, IL-2 and IL-4 decreased by immobilization stress. Also, KJT enhanced the phagocytic activity decreased by immobilization stress and enhanced the level of nitric oxide decreased by immobilization stress. These results indicate that KJT may be useful for the prevention and treatment of stress via suppression of serum histamine and corticosterone level and enhancement of specific- and nonspecific-immune response.
참고문헌 (59)
- "傅靑主男女科", pp.102~9 (1992), 大星文化社
- "臨床婦産科學", pp.318~25 (1988), 成輔社
- "漢方婦人科學", pp.263~269 (1995), 杏林出版社
- "韓醫婦人科學(上)", pp.245~255 (2001), 정담
- "The stress of life", pp.1~50 (1958)
- "Perspective in behavioral medicine" (1981), Academic Press
- "Syndrome produced by diverse nocuous agents" (1936)
- "Peptidehormones shared by the neuroendocrine and immunologic systems", immu(l) (1985)
- "Epineprine 및 疼痛刺戟에 의한 免疫反應變調" (1988)
- "熱 및 寒冷 스트레스가 마우스의 免疫反應에 미치는 影響" (1983)
- "Effects of Glycyrrhizae Radix on serum corticosterone and blood histamine content by immobilization stress in mice", pp.37~42 (1989)
- "逍遙散이 생쥐에 Immobilization Stress 負荷 後 血中 免疫能系에 미치는 影響", 16(3), pp.101~127 (2003)
- "In methods in Enzymology", pp.94~100 (1983), Academic Press
- "Planning for lymphocytes A method for cell selection", pp.75~2844 (1978)
- "Characterization of lymphocyte-activating factor produced by the macrophage cell line P388D1", immu(l) (1979)
- "Rapid colorimetric assay for cellular growth and survival application to proliferation and cytotoxic assays", immu(l) (1983)
- "A simple and rapid method to determine hematopoietic growth factor activity", immu(l) (1990)
- "Rapid and simple method for mesuring thymocyte apoptosis by propidium iodide staining and flow cytometry", immu(l) (1991)
- "Purification and characterization of the Fas-ligand that induces apoptosis", pp.873~9 (1994)
- "Regulation of cytokine production by exogenous nitric oxide in murine splenocyte and peritoneal macrophage", 23(5), pp.531~534 (2000)
- "Chemiluminenscence and nitrite determinations by the MALU macrophage cell line", immu(l) (1994)
- "Measurement of phagocyte chemiluminenscence in a microtiter plate format", immu(l) (1988)
- "Killing of Plasmodium falciparum in vitro by nitric oxide derivatives" (1991)
- "Stress에 關한 文獻的 考察", pp.38~50 (1991)
- "스트레스의 槪念에 對한 韓醫學的 解釋", 3(1), pp.119~151 (1997)
- "加味逍遙散의 效能에 關한 實驗的 硏究", 9(1), pp.41~53 (1996)
- "스트레스 상황이 면역반응에 미치는 영향에 관한 연구", 1(1), pp.35~54 (1993)
- "Stress and anxiety", 25(4), pp.935~94 (1990)
- "The concepts of stress and stress system disorders Overview of physical and behavioural homeostasis", pp.1244~52 (1992)
- "The neuroendocrinology of stress from invertebrates to man", 48, pp.421~440 (1996)
- "Central H1- and H2-histaminergic stimulation of pituitary-adrenocortical response under stress in rats", neuroendocri(logy), pp.424~30 (1983)
- "Modulation of stress-induced ACTH release by corticotropin-releasing factor", pp.325~327 (1983), catecholamines and vasopressin
- "Effect of serotonin-releasing drugs on serum corticosterone concentration in rat", neuroendocri(logy), pp.96~100 (1980)
- "Evidence for a role of endogenous corticotropin-releasing factor in cold", pp.1247~51 (1985)
- "Adrenal sensitivity to adrenocorticotropin varies diurnally", endocri(logy), pp.70~5 (1981)
- "Stress-induced suppression of immunity in adrenalectomized rats", pp.1301~4 (1983)
- "an integrated view of relationships between the brain and the immune KJTtem"
- "Effects of repeated stress on T cell numbers and function in rats", pp.105~17 (1990)
- "Stress causes reduced natural killer activit in mice", immu(l), pp.461~4 (1983), Aarstad
- "Effects of berberine on serum levels of catecholamines after immobilization stress in mic", 7(2), pp.81~85 (1997)
- "Effects of surgical stress on natural killer activity proliferative response of spleen cells and cytostatic activity of lung macrophages in arts", pp.790~4 (1991)
- "Prevention of immunosuppression in stressed mice by neurotropin", pp.869~76 (1990)
- "Effects of buspirone on the immunosuppressive response to stress in mice", pp.160~8 (1991)
- "Effects of midazolam on T-cell immunosuppressive response to surgical stress in mice", pp.85~9 (1992)
- "Effects of alprazolam on T-cell immunosuppressive response to surgical stress in mice"
- "Influence of stress on the maturity of T-cells", pp.1571~81 (1991)
- "evidence for stressor-induced time-dependent sensitization of the immune KJTtem", pp.579~90 (1990), earlier enhanced 2-deoxy-D-glucose-induced immunosuppression
- "Prenatal stress depresses immune function in rats", 63(3), pp.397~402 (1998)
- "Stress and the immune system", 83(5), pp.214~220 (1996)
- "Differential immune reactivity to stress in BALB", cByJ and C57BL, pp.1, 65(1)[DOI]
- "Significance of increased secretion of glucocorticoids in mice and rats injected with bacterial endotoxin", pp.159~72 (1987)
- "Repeated restraint stress impairs the antitumor T cell response through its suppressive effect on Th1-type CD4+ T cells", 17(6D), pp.4259~4268 (1997)
- "Stressor-induced alteration of lymphocyte proliferation in mice evidence for enhancement of mitogenic responsiveness", pp.269~77 (1990)
- "Cold-stress induces thymocyte apoptosis in the rat", 4, pp.213~219 (1997)
- "Restraint stress causes tissue-specific changes in the immune cell distribution", 4(3), pp.113~119 (1997)
- "The role of CD4 and CD8 in T cell activation and differentiation Advances in Immunology" (1993)
- "Repeated restraint stress impairs the antitumor T cell response through its suppressive effect on Th1-type CD4+ T cells", 17(6D), pp.4259~4268 (1997)
- "Interlations of natural cellular cytotoxicity and interferon KJTtems in immobilization stress", pp.593~5 (1984)
- "Nitric oxide inhibits macrophage pseudopodia formation in the activated macrophages", 18, pp.635~644 (1996)
