The Relaxant Activity of Safranal in Isolated Rat Aortas is Mediated Predominantly via an Endothelium-Independent Mechanism - Vasodilatory mechanism of safranal -

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참고문헌 (37)

1. Sandoo A, "The endothelium and its role in regulating vascular tone", Open Cardiovasc Med J, 4, pp.302~312 (2010)
2. Dharmashankar K, "Vascular endothelial function and hypertension: insights and directions", Curr Hypertens Rep, 12(6), pp.448~455 (2010)
3. Veeramani C, "Antihypertensive effect of Melothria maderaspatana leaf fractions on DOCA-salt-induced hypertensive rats and identification of compounds by GC-MS analysis", J Nat Med, 66(2), pp.302~310 (2012)
4. Krum H, "New and emerging drug treatments for hypertension", Aust Fam Physician, 27(4), pp.235~237 (1998)
5. Talha J, "Hypertension and herbal plants", Int Res J Pharm, 2(8), pp.26~30 (2011)
6. Hosseinzadeh H, "Avicenna's(Ibn Sina)the canon of medicine and saffron(Crocus sativus) : a review", Phytother Res, 27(4), pp.475~483 (2013)
7. Hosseinzadeh H, "Anticonvulsant effects of aqueous and ethanolic extracts of Crocus sativus L. stigmas in mice", Arch Iran Med, 5, pp.44~47 (2002)
8. Hosseinzadeh H, "Antidepressant effect of Crocus sativus L. Stigma extracts and their constituents, crocin and safranal, in Mice", J Med Plants, 3, pp.48~58 (2004)
9. Faezeh Vahdati Hassani, "Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus", DARU Journal of Pharmaceutical Sciences, 22(1), pp.16~ (2014), Springer Nature[DOI]
10. Ghasemi T, "Antidepressant effect of Crocus sativus aqueous extract and its effect on CREB, BDNF, and VGF transcript and protein levels in rat hippocampus", Drug Res, 65(7), pp.337~343 (2015)
11. Hossein Hosseinzadeh, "Antinociceptive and anti- inflammatory effects of Crocus sativus L. stigma and petal extracts in mice", BMC Pharmacology, 2(1), pp.7~ (2002), Springer Nature[DOI]
12. Hosseinzadeh H, "Antioxidant activity of aqueous and ethanolic extracts of Crocus sativus L. stigma and its bioactive constituents crocin and safranal", Pharmacogn Mag, 5(20), pp.419~424 (2010)
13. Abdullaev FI, "Biological effects of saffron", Biofactors, 4(2), pp.83~86 (1993)
14. Hosseinzadeh H, "Anti-tumor and cytotoxic evaluation of Crocus sativus L. stigma and petal extracts using brine shrimp and potato disc assays", J Med Plants, 4(15), pp.59~65 (2005)
15. Imenshahidi M, "Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats", Phytother Res, 24(7), pp.990~994 (2010)
16. Imenshahidi M, "Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats", Iran J Basic Med Sci, 17(1), pp.9~13 (2014)
17. Bibi Marjan Razavi, "Saffron as an antidote or a protective agent against natural or chemical toxicities", DARU Journal of Pharmaceutical Sciences, 23(1) (2015), Springer Nature[DOI]
18. Bathaie SZ, "New applications and mechanisms of action of saffron and its important ingredients", Crit Rev Food Sci Nutr, 50(8), pp.761~786 (2010)
19. Alavizadeh SH, "Bioactivity assessment and toxicity of crocin: a comprehensive review", Food Chem Toxicol, 64, pp.65~80 (2014)
20. Rezaee R, "Safranal: from an aromatic natural product to a rewarding pharmacological agent", Iran J Basic Med Sci, 16(1), pp.12~26 (2013)
21. Assimopoulou AN, "Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents", Phytother Res, 19(11), pp.997~1000 (2005)
22. Hosseinzadeh H, "Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice", Fitoterapia, 76(7-8), pp.722~724 (2005)
23. Nemati H, "Stimulatory effect of Crocus sativus (saffron) on β2-adrenoreceptors of guinea pig tracheal chains", Phytomedicine, 15(12), pp.1038~1045 (2008)
24. Amin B, "Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L. and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats", Fitoterapia, 83(5), pp.888~895 (2012)
25. Hosseinzadeh H, "Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus", J Pharm Pharm Sci, 8(3), pp.394~399 (2005)
26. Hosseinzadeh H, "Effects of Crocus sativus stigma extract and its constituents, crocin and safranal, on intact memory and scopolamine-induced learning deficits in rats performing the Morris water maze task", J Med Plants, 5, pp.40~50 (2006)
27. Boskabady MH, "Effect of aqueous-ethanol extract from Crocus sativus (saffron) on guinea-pig isolated heart", Phytother Res, 22(3), pp.330~334 (2008)
28. Mehdizadeh R, "Cardioprotective effect of saffron extract and safranal in isoproterenol-induced myocardial infarction in wistar rats", Iran J Basic Med Sci, 16(1), pp.56~63 (2013)
29. Imenshahidi M, "The effect of chronic administration of safranal on systolic blood pressure in rats", Iran J Pharm Res, 14(2), pp.585~590 (2015)
30. Parsaee H, "Lovastatin incubation improves acetylcholine-induced relaxation in isolated aortic rings of diabetic rat", Iran J Pharm Res, 5(3), pp.191~198 (2006)
31. Boskabady MH, "Relaxant effect of Crocus sativus (saffron) on guinea pig tracheal chains and its possible mechanisms", J Pharm Pharmacol, 58(10), pp.1385~1390 (2006)
32. Mombouli JV, "Endothelial dysfunction : from physiology to therapy", J Mol Cell Cardiol, 31(1), pp.61~74 (1999)
33. Dehpour AR, "The effect of lithium on endothelial-dependent relaxation in rat isolated aorta", Gen Pharmacol, 26(5), pp.1003~1007 (1995)
34. Sausbier M, "Mechanisms of NO", cGMP-dependent vasorelaxation, 2000, pp.87(9), 825~830
35. Mashhoodi T, "Inhibitory effect of aluminium on KCl and phenylephrine induced contraction in isolated rat aorta", Acta Medica Iranica, 42(5), pp.379~382 (2004)
36. Nugent M, "Cerebral metabolic vascular and protective effects of midazolam maleate: comparison to diazepam", Anesthesiology, 56(3), pp.172~176 (1982)
37. Hosseinzadeh H, "Acute and subacute toxicity of safranal, a constituent of saffron, in mice and rats", Iran J Pharm Res, 12(1), pp.93~99 (2013)

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