일부 어린이 해열·진통제의 유치 법랑질 부식효과
Effects of the Enamel Erosion Caused by Certain Antipyretic and Analgesic Medicines for Children
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
This study was conducted to provide basic understanding regarding possible enamel erosion by three kinds of first-aid antipyretic and analgesic medicines over a period of time, with comparison and analysis of the resulting deciduous teeth surface and microhardness changes. The analysis was performed using energy dispersive X-ray spectroscopy (EDX) and scanning electron microscope (SEM) to examine the surface erosion and changes. The Kruskal-Wallis test show differences in surface erosion and changes after 3, 5 and 8 days of treatment as well as before and after the treatment in each group. According to the results, there was no significant difference in the early deciduous teeth enamel surface microhardness (p＞0.01). However there were signigicant changes after 3, 5, and 8 days (p＜0.01). Calcim (Ca) and phosphorous (P) analysis using EDX showed significant differences in the enamel characteristics according to each tissue area after 8 days (p＜0.05), but there was no significant difference in any of the areas for P content (p＞0.05). In the surface observation with the SEM treatment with Children’s TylenolⓇ tablet, which has the lowest pH, looked the roughest, followed by Brufen syrup for children and Children's TylenolⓇ suspension. Based on these results, it should be considered that antipyretic and analgesic medicines for children, which have lower pH values, may cause tooth erosion. Hence, it is necessary to give special attention to oral hygiene in young children or infants by brushing their teeth after such drugs are administered.
Abstract
This study was conducted to provide basic understanding regarding possible enamel erosion by three kinds of first-aid antipyretic and analgesic medicines over a period of time, with comparison and analysis of the resulting deciduous teeth surface and microhardness changes. The analysis was performed using energy dispersive X-ray spectroscopy (EDX) and scanning electron microscope (SEM) to examine the surface erosion and changes. The Kruskal-Wallis test show differences in surface erosion and changes after 3, 5 and 8 days of treatment as well as before and after the treatment in each group. According to the results, there was no significant difference in the early deciduous teeth enamel surface microhardness (p＞0.01). However there were signigicant changes after 3, 5, and 8 days (p＜0.01). Calcim (Ca) and phosphorous (P) analysis using EDX showed significant differences in the enamel characteristics according to each tissue area after 8 days (p＜0.05), but there was no significant difference in any of the areas for P content (p＞0.05). In the surface observation with the SEM treatment with Children’s TylenolⓇ tablet, which has the lowest pH, looked the roughest, followed by Brufen syrup for children and Children's TylenolⓇ suspension. Based on these results, it should be considered that antipyretic and analgesic medicines for children, which have lower pH values, may cause tooth erosion. Hence, it is necessary to give special attention to oral hygiene in young children or infants by brushing their teeth after such drugs are administered.
참고문헌 (20)
- 황민성, "경구용 액체약에 함유된 감미제의 종류와 함량", 대한소아치과학회지, 28(4), pp.661~667 (2001), 대한소아치과학회
- 김상희, "아동의 발열에 대한 부모의 지식, 불안 및 대처방법", 석사, 간호과학, pp.2008
- Kim JS, "Pediatric dentistry", pp.20~26 (2011), DaehanNarae Publishing Inc
- Preventive Dentistry Research Society, "Preventive dentistry", pp.51~66 (2010), Koonja
- Eee KO, "Illustrated dental terminology", pp.35~ (2010), Komoonsa
- Kim SK, "Conservative dentistry", pp.22~ (2010), DaehanNarae Publishing Inc.
- 정문진, "A Study on the Enamel Erosion Caused by Energy Drinks", 치위생과학회지, 14(4), pp.597~609 (2014), 한국치위생과학회
- 오한나, "에너지 음료가 법랑질 부식에 미치는 영향", 치위생과학회지, 15(4), pp.419~423 (2015), 한국치위생과학회
- 임도선, "시판 탄산수에 의한 우치 법랑질 침식과 침착 효과", 치위생과학회지, 15(4), pp.437~444 (2015), 한국치위생과학회
- Lee KO, "Long-term effects of syrup medication for asthma on the salivary invertase activity and deciduous caries", J Korean Acad Pdiatr Dent, 25, pp.421~429 (1998)
- Costa CC, "Erosive effect of an antihistamine containing syrup on primary enamel and its reduction by fluoride dentifrice", Int J Paediatr Dent, 16, pp.174~180 (2006)
- 안지영, "유아용 시럽형 약물이 구강 내 산도에 미치는 영향", 대한소아치과학회지, 34(4), pp.590~598 (2007), 대한소아치과학회
- Valinoti AC, "In vitro alterations in dental enamel exposed to acids medicines", Int J of Paediatr Dent, 21, pp.141~150 (2011)
- Sunitha S, "An analysis of concentration of sucrose, endogenous pH, and alteration in the plaque pH on consumption of commonly used liquid pediatric medicines", J Indian Soc Pedod Prevent Dent, 27, pp.44~48 (2009)
- West NX, "Erosion of dentine and enamel in vitro by acids: the effect of temperature, acid character, concentration and exposure time", J Oral Rehabil, 27, pp.875~880 (2000)
- 임화신, "어린이용 시럽제의 우식유발능에 대한 생체 외 연구", 대한소아치과학회지, 38(2), pp.146~154 (2011), 대한소아치과학회
- 이창윤, "오렌지쥬스의 치아 법랑질 침식효과에 대한 연구", 대한소아치과학회지, 31(4), pp.617~623 (2004), 대한소아치과학회
- Ahn HY, "Erosion of tooth enamel by acidic drinks and drmineralization by arificial saliva", J Korean Acad Pediatr Dent, 11, pp.357~367 (2002)
- Nankar M, "Comparative evaluation of cariogenic and erosive potential of commonly prescribed pediatric liquid medicaments", J Contemp Dent Pract, 15, pp.20~25 (2014)
- Tupalli AR, "Evalutation of the erosive potential of various pediatric liquid medicaments", J Int Oral Health, 6, pp.59~65 (2014)