Bovine teeth에 대한 어린이용 영양제의 우식유발능
Cariogenic Potential of Nutritional Supplements for Children on Bovine Teeth
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초록
어린이용 영양제의 우식 유발능에 관해 알아보기 위하여 국내에서 시판 중인 건강기능식품 어린이용 영양제 4종에 대한 생체외 연구를 시행하였다. 어린이용 영양제 4종을 실험군으로, 10% 자당을 양성 대조군, 인공 타액을 음성 대조군으로 하였다. 실험군 및 대조군의 pH, 완충능, 산생성능, 우치 법랑질 침식능을 검사하였다. 실험군 4종의 pH 모두 탈회 임계 pH인 5.5보다 낮았다. 완충능은 Hama Vitamin Pharm이 가장 크고, SmartChewable Vitamin A가 가장 작았다. 4개의 실험군은 음성 대조군보다 유의하게 높은 산생성능을 보였다(p < 0.05). 우치법랑질 침식능 검사 결과, 4종의 실험군과 양성 대조군에서 표면미세경도가 유의하게 감소하였다(p < 0.05). 표면미세경도감소율은 실험군 중에서 Hama Vitamin Pharm이 유의하게 높았고, Hikid Plus는 유의하게 낮았다(p < 0.05).
Abstract
An in vitro study on cariogenic potential of four over-the-counter nutritional supplements for children wasperformed. The experimental groups were four over-the-counter nutritional supplements. The positive controlgroup was 10% sucrose solution (S), and the negative control group was artificial saliva (T). The pH of each group,the buffering capacities, acid production, the microhardness changes of the bovine teeth specimens were measured. The pH of all experimental groups were lower than critical pH 5.5 where enamel demineralization starts. Thebuffering capacity of the Hama Vitamin Pharm (Hamsoa Pharm Co., Korea) was highest, and the SmartChewable Vitamin A (JW Pharm Co., Korea) had the lowest buffering capacity. The reduction rates of the pH ofthe experimental groups were significantly higher than that of the negative control group (p < 0.05). The microhardnessof enamel of all experimental groups and the positive control group significantly decreased. In contrast,the microhardness of enamel of the negative control group significantly increased after experiment (p < 0.05). The reduction rate of the microhardness of enamel of the Hama Vitamin Pharm (Hamsoa Pharm Co., Korea)was significantly higher and Hikid Plus (Sanga Pharm Co., Korea) was significantly lower than the other experimentalgroups.
참고문헌 (31)
- Edelstein BL, "Disparities in oral health and access to care : Findings of national surveys", Ambulatory Pediatrics, 2, pp.141~147 (2002)
- HEO SH, "The present condition & development for labeling and advertising system of health functional food", Food Science and Industry, 40, pp.11~15 (2007)
- 김선효, "우리나라 일부 초등학생의 건강기능식품 섭취 실태", Journal of Nutrition and Health, 43(2), pp.161~170 (2010), 한국영양학회
- Song BC, "Patterns of vitamin-mineral supplement use among preschool children in Korea", Korean J Nutr, 31, pp.1066~1075 (1998)
- Kim SH, "Vitamin and mineral supplement use among children attending elementary schools in Korea : a survey of eating habits and dietary consequences", Nutrition Research, 22, pp.433~448 (2002)
- 박진선, "대전지역 학령기 아동의 건강기능식품 섭취실태 및 부모의 요구도", 대한지역사회영양학회지, 13(4), pp.463~475 (2008), 대한지역사회영양학회
- 김선효, "우리나라 일부 청소년의 건강기능식품 섭취 실태", Journal of Nutrition and Health, 38(10), pp.864~872 (2005), 한국영양학회
- Lingstrom P, "The pH of dental plaque in its relation to early enamel caries and dental plaque flora in human", J Dent Res, 79, pp.770~777 (2000)
- van Ruyven FO, "Relationship among mutans streptococci, “low-pH”bacteria, and lodophilic polysaccharide-producing bacteria in dental plaque and early enamel caries in humans", J Dent Res, 79, pp.778~784 (2000)
- van Houte J, "Role of micro-organisms in caries etiology", J Dent Res, 7, pp.672~681 (1994)
- Dibdin GH, "Physical and biochemical studies of Streptococcus mutans sediments suggest new factors linking the cariogenicity of plaque with its extracellular polysaccharide content", J Dent Res, 67, pp.890~895 (1988)
- Dodds MWJ, "Effects of dietary sucrose levels on pH fall and acid-anion profile in human dental plaque after a starch mouth-rinse", Archs Oral Biol, 31, pp.509~512 (1986)
- Sgan-Cohen HD, "The effect of previous diet on plaque pH response to different foods", J Dent Res, 67, pp.1434~1437 (1988)
- Stephan RM, "Intra-oral hydrogen-ion concentrations associated with dental caries activity", J Dent Res, 23, pp.257~266 (1944)
- Abelson DC, "The effect of saliva on plaque pH in vivo", J Dent Res, 60, pp.1634~1638 (1981)
- Kim JB, "Clinical preventive dentistry", pp.314~315 (2005), Komoonsa
- Hase JC, "Oral retention of glucose at pharmacologically reduced salivary flow in man", Scand J Dent Res, 102, pp.180~185 (1994)
- Yu KJ, "An analytical study on the flow rate, viscosity, buffering capacity and inorganic composition of whole saliva", J Korean Acad Oral Health, 15, pp.55~69 (1999)
- 신혜성, "유산균 발효유가 Streptococcus mutans의 생균수 및 biofilm 형성에 미치는 영향", 대한소아치과학회지, 36(3), pp.358~366 (2009), 대한소아치과학회
- 임화신, "어린이용 시럽제의 우식유발능에 대한 생체 외 연구", 대한소아치과학회지, 38(2), pp.146~154 (2011), 대한소아치과학회
- Hur YW, "In vitro study of baby food and breakfast cereal as for buffering capacity, acid production by Streptococcus mutans, and synthetic hydroxyapatite decalcification", J WonKwang Dent Res, 1, pp.167~176 (1990)
- Loesche WJ, "Role of Streptococcus mutans in human dental decay", Microbiol. Rev, 50, pp.353~380 (1986)
- Aranibar QEM, "Influence of short-term sucrose exposure on plaque acidogenicity and cariogenic microflora in individuals with different levels of mutans streptococci", Caries Res, 37, pp.51~57 (2003)
- Korean Acad Pediatr Dent, "Dentistry for the child and adolescent", pp.173~174 (2007), Shin-hung international
- Amaechi BT, "Techniques for the production of dental eroded lesions in vitro", J Oral Rehabil, 26, pp.97~102 (1999)
- Valinoti AC, "In vitro alterations in dental enamel exposed to acidic medicines", Int J Paediatr Dent, 21, pp.141~150 (2011)
- Schilke R, "Comparison of the number and diameter of dentinal tubules in human and bovine dentine by scanning electron microscopic investigation", Archs Oral Biol, 45, pp.355~361 (2000)
- Camargo CHR, "Topographical, diametral, and quantitative analysis of dentin tubules in the root canals of human and bovine teeth", J Endod, 33, pp.422~426 (2007)
- Camargo MA, "Morphological analysis of human and bovine dentine by scanning electron microscope investigation", Archs Oral Biology, 53, pp.105~108 (2008)
- Zax MS, "Carbonate content in developing human and bovine enamel", J Dent Res, 70, pp.913~916 (1991)
- Ban MJ, "Sweetener content of common pediatric oral liquid and chewable tablet medications", J Korean Soc Hosp Pharm PP, 8, pp.93~99 (1991)