치주질환과 당뇨병의 관련성
An Association of Periodontitis and Diabetes
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초록
This study was conducted to evaluate the association between periodontal disease and diabetes mellitus. The final analysis population of this studywas composed of 4,830 adults with diabetes mellitus or periodontal disease and aged 19 years or older, based on the third-edition data of the 4thKorea National Health and Nutrition Examination Survey (KNHANES) (in 2009). Diabetic status and potential confounders were used inquestionnaire materials and physical examination materials, and the presence of periodontal disease was used in the materials for oral healthexamination by a dentist. For diabetic status, fasting plasma glucose (FPG) levels ＜100 mg/dl were subcategorized into normal group and FPGlevels ≥100 mg/dl into impaired fasting glucose group; glycosylated hemoglobin (HbA1c) levels ＜7% into normal group and HbA1c ≥7% intodiabetes group, on the basis of the American Diabetes Association. According to the 2009 Korea Health Statistics, the case where the pocket depthis 3 mm or more was defined as periodontal disease. The association between the two diseases was evaluated through χ2-test and logisticregression analysis using R-commander 2.14. In impaired fasting glucose group, community periodontal index (CPI) groups 3 to 4 had higher risksfor periodontal disease 1.23 times (95% confidence interval, 1.07∼1.42) than those of CPI groups CPI 0∼2, even after adjustment for severalconfounders. In addition, periodontal disease and diabetes mellitus showed statistically significant differences depending on age, sex, income level,educational background, smoking status, alcohol consumption, and snack intake. The analyses of the third-edition data of the 4th KNHANESshowed that there was a statistically significant association between periodontal disease and diabetes mellitus as examined by means of CPI in this study.
Abstract
This study was conducted to evaluate the association between periodontal disease and diabetes mellitus. The final analysis population of this studywas composed of 4,830 adults with diabetes mellitus or periodontal disease and aged 19 years or older, based on the third-edition data of the 4thKorea National Health and Nutrition Examination Survey (KNHANES) (in 2009). Diabetic status and potential confounders were used inquestionnaire materials and physical examination materials, and the presence of periodontal disease was used in the materials for oral healthexamination by a dentist. For diabetic status, fasting plasma glucose (FPG) levels ＜100 mg/dl were subcategorized into normal group and FPGlevels ≥100 mg/dl into impaired fasting glucose group; glycosylated hemoglobin (HbA1c) levels ＜7% into normal group and HbA1c ≥7% intodiabetes group, on the basis of the American Diabetes Association. According to the 2009 Korea Health Statistics, the case where the pocket depthis 3 mm or more was defined as periodontal disease. The association between the two diseases was evaluated through χ2-test and logisticregression analysis using R-commander 2.14. In impaired fasting glucose group, community periodontal index (CPI) groups 3 to 4 had higher risksfor periodontal disease 1.23 times (95% confidence interval, 1.07∼1.42) than those of CPI groups CPI 0∼2, even after adjustment for severalconfounders. In addition, periodontal disease and diabetes mellitus showed statistically significant differences depending on age, sex, income level,educational background, smoking status, alcohol consumption, and snack intake. The analyses of the third-edition data of the 4th KNHANESshowed that there was a statistically significant association between periodontal disease and diabetes mellitus as examined by means of CPI in this study.
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