Effective Medicinal Plants in the Treatment of the Cyclic Mastalgia (Breast Pain): A Review
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Introduction: Mastalgia is the most common benign breast disorder during the fertility period of women. So far a wide range of natural or complementary medicines is used to cure mastalgia. Sanitary organizations need complete and suitable details to help women, for making the proper decision for alternative treatment based on the evidence. The aim of the present study is to introduce medicinal plant-based treatments about mastalgia and summarizes clinical trials about this disorder. Method: The articles were provided using mixture of keywords including cyclic pain, breast, treatment, therapeutics, therapy, clinical trial, herbal, drug, mastalgia and all the probable terms, in national and international databases SID, Iran Medex, Magiran, PubMed, Scopus, Medline, Science direct and Cochrane library, in both Persian and English languages. All cross-sectional and review articles about herbal treatment of mastalgia until 2018 November were studied. Results: Nineteen articles from all of the available articles (45 cases) and a sample size about of (1987 cases) were included in our study. The articles were clinical trials. The results revealed that mastalgia could be healed by Nigella sativa, Vitex agnus-castus, curcumin, Hypericum perforatum, Citrus sinensis, wheat germ, and Ginkgo biloba. Conclusion: Most of the evaluated medicinal plants possessing antioxidant compounds with anti-inflammatory and analgesic properties, exhibited healing effects in the treatment of mastalgia. Thus, medicinal plants can be considered in the treatment of mastalgia; however, further investigations are needed to obtain more details about their probable side effects.
Abstract
Introduction: Mastalgia is the most common benign breast disorder during the fertility period of women. So far a wide range of natural or complementary medicines is used to cure mastalgia. Sanitary organizations need complete and suitable details to help women, for making the proper decision for alternative treatment based on the evidence. The aim of the present study is to introduce medicinal plant-based treatments about mastalgia and summarizes clinical trials about this disorder. Method: The articles were provided using mixture of keywords including cyclic pain, breast, treatment, therapeutics, therapy, clinical trial, herbal, drug, mastalgia and all the probable terms, in national and international databases SID, Iran Medex, Magiran, PubMed, Scopus, Medline, Science direct and Cochrane library, in both Persian and English languages. All cross-sectional and review articles about herbal treatment of mastalgia until 2018 November were studied. Results: Nineteen articles from all of the available articles (45 cases) and a sample size about of (1987 cases) were included in our study. The articles were clinical trials. The results revealed that mastalgia could be healed by Nigella sativa, Vitex agnus-castus, curcumin, Hypericum perforatum, Citrus sinensis, wheat germ, and Ginkgo biloba. Conclusion: Most of the evaluated medicinal plants possessing antioxidant compounds with anti-inflammatory and analgesic properties, exhibited healing effects in the treatment of mastalgia. Thus, medicinal plants can be considered in the treatment of mastalgia; however, further investigations are needed to obtain more details about their probable side effects.
참고문헌 (59)
- Vaziri F, "Comparing the effects of dietary flaxseed and omega-3 Fatty acids supplement on cyclical mastalgia in Iranian women: a randomized clinical trial", International journal of family medicine (2014)
- Aydin Y, "Cabergoline versus bromocriptine for symptomatic treatment of premenstrual mastalgia: a randomised, open-label study", European Journal of Obstetrics & Gynecology and Reproductive Biology, 150(2), pp.203~206 (2010)
- Genç A, "The effects of exercise on mastalgia", The Physician and sportsmedicine, 45(1), pp.17~21 (2017)
- Pruthi S, "Vitamin E and evening primrose oil for management of cyclical mastalgia : a randomized pilot study", Altern Med Rev, 15(1), pp.59~67 (2010)
- Jatoi I, K.M., "Management of Breast Diseases" (2010), Springer Berlin Heidelberg
- Shobeiri F, "Clinical effectiveness of vitamin E and vitamin B6 for improving pain severity in cyclic mastalgia", Iranian journal of nursing and midwifery research, 20(6), pp.723~ (2015)
- Berek JS, "Berek & Novak’s gynecology" (2012), Williams & Wilkins
- Murshid K R., "A review of mastalgia in patients with fibrocystic breast changes and the non-surgical treatment options", Journal of Taibah University Medical Sciences, 6(1), pp.1~18 (2011)
- Sharami S, "PREVALENCE OF CYCLIC MASTALGIA AND IT'S RELATION WITH AGE" (2000), MARRIAGE AND EMPLOYMENT OUTSIDE THE HOUSE
- Alvandipour M, "Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia", Journal of Babol University Of Medical Sciences, 13(2), pp.7~11 (2011)
- Jaafarnejad F, "Comparison of the Effect of Fish Oil and Vitamin E on the Severity of Cyclic Mastalgia", The Iranian Journal of Obstetrics, Gynecology and Infertility, 15(39), pp.9~15 (2013)
- Smith RL, "Evaluation and management of breast pain", Mayo Clinic Proceedings (2004), Elsevier
- Srivastava JK, "Chamomile : A herbal medicine of the past with bright future", Molecular medicine reports, 3(6), pp.895~901 (2010)
- Salami M, "effect of salinity on morphological changes of Cuminum cyminum and Valeriana officinalis", Research and construction, 19(3), pp.77~83 (2007)
- Seraji A, "The Effects of Evening Primrose and Vitex Agnus on Pain Scale of the Women with Cyclic Mastalgia A Clinical Trial", Complementary Medicine Journal of faculty of Nursing & Midwifery, 3(4), pp.639~653 (2014)
- Fong HH, "Integration of herbal medicine into modern medical practices: issues and prospects", Integrative cancer therapies, 1(3), pp.287~293 (2002)
- Morikawa T, "Novel Dolabellane-Type Diterpene Alkaloids with Lipid Metabolism Promoting Activities from the Seeds of Nigella s ativa", Organic letters, 6(6), pp.869~872 (2004)
- Morikawa T, "Nigellamines A3, A4, A5, and C, new dolabellane-type diterpene alkaloids, with lipid metabolism-promoting activities from the Egyptian medicinal food black cumin", Chemical and pharmaceutical bulletin, 52(4), pp.494~497 (2004)
- Nickavar B, "Chemical composition of the fixed and volatile oils of Nigella sativa L. from Iran", Zeitschrift für Naturforschung C, 58(9-10), pp.629~631 (2003)
- Al-Ghamdi M., "The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa", Journal of ethnopharmacology, 76(1), pp.45~48 (2001)
- Mirmolaei ST, "The effect of Nigella Sativa syrup on the relief of cyclic mastalgia : A triple-blind randomized clinical trial", Journal of hayat, 23(1), pp.33~43 (2017)
- Shahhosseini Z, A.G, "Clinical evaluation of anti- dysmenorrhea vitagnus", journal of Mazandaran University of medical science, 15(50), pp.15~21 (2006)
- Salehi A, "Comparison of the effects of Hypericum and Vitex agnus premenstrual syndrome compared with vitamin E : a randomized clinical trial", Complementary Medicine Journal of faculty of Nursing & Midwifery, 3(1), pp.395~405 (2013)
- Mirmolaei S, "The Effect of Vitagnus on Cyclic Breast Pain in Women of Reproductive Age", Journal of Babol University of Medical Sciences, 18(9), pp.7~13 (2016)
- Sekhavat L, "The effect of vitex agnus-castus on mastalgia in women", Iranian South Medical Journal, 11(2), pp.147~152 (2009)
- Halaska M, "Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract : results of a placebo-controlled double-blind study", The Breast, 8(4), pp.175~181 (1999)
- Moridani AS., "Effect of Nigella sativa and Vitex agnus on severity mastalgia durig the female reproductive. School of Nursing and Midwifery", Journal of Tehran University of Medical Sciences (2015)
- Ghasemnezhad A, "Yield, oil constituents, and protein content of evening primrose (Oenothera biennis L.) seeds depending on harvest time, harvest method and nitrogen application", Industrial crops and products, 28(1), pp.17~23 (2008)
- Cornish S, "The role of vitamins and minerals in psychiatry", Integrative medicine insights, 3, pp.33~ (2008)
- Fathizadeh N, "Effects of evening primrose oil and vitamin E on the severity of periodical breast pain", Iranian Journal of Nursing and Midwifery Research, 13(3) (2009)
- Momeni H, "The Effects of Vitex Agnus Castus and Vitamin E on Anxiety in women with Mastalgia: A Randomized Clinical Trial", Knowledge & Health, 2(9) (2013)
- Meschino JP, "Flaxseed supplementation : an integral aspect of vibrant health", Dynamic Chiropract, 21(2), pp.34~ (2003)
- R, B., "Novel herbal therapy" (2005), motarjem
- Ingram D, "A double-blind randomized controlled trial of isoflavones in the treatment of cyclical mastalgia", The Breast, 11(2), pp.170~174 (2002)
- Thompson L. U, "Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer", Clinical cancer research, 11(10), pp.3828~3835 (2005)
- Jaafarnejad F, "Compare the effect of flaxseed, evening primrose oil and Vitamin E on duration of periodic breast pain", Journal of Education and Health Promotion, 6, pp.85~ (2017)
- Vaezi G, "Interaction Of Antinociceptive Intraperitoneal Injection Of Extract Of Foeniculum Vulgare Fruit And Morphine In Mice", Journal Of Animal Biology, 2, pp.57~63 (2010)
- DELARAM M, "The effect of fennel on the pre-menstrual syndrome", KNOWLEDGE AND HEALTH, 6, pp.1~6 (2011)
- Sadraei H, "Study of the effect of hydro-alcholic and essential oil of Echinophora platyloba on rat isolated ileum contractions in vitro", JOURNAL OF RESEARCH IN MEDICAL SCIENCES(JRMS), 7, pp.150~155 (2003)
- Delaram M, "Comparing the effects of Echinophora-platyloba, Fennel and Placebo on pre-menstrual syndrome", Journal of reproduction & infertility, 12(3), pp.221~ (2011)
- Barnes J, "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties", Journal of pharmacy and pharmacology, 53(5), pp.583~600 (2001)
- Pakgohar M, "Effect of Hypericum perforatum L. for treatment of premenstrual syndrome", Journal of Medicinal Plants, 3(15), pp.33~42 (2005)
- Zarghami M, "Anti depressant effects of Rosa Damascena on laboratory rats(A controlled experimental blind study)", Journal of Mazandaran University of Medical Sciences, 11(33), pp.27~33 (2001)
- Jamilian M, "Rose Damascena vs. Omega-3 in the Treatment of Premenstural Syndrome:A randomized , and Placebo-Controlled Clinical Trial", complementary Medicine Journal, 3(3), pp.541~551 (2013)
- Singh N, "Therapeutic potential of organic Triticum aestivum Linn.(Wheat Grass) in prevention and treatment of chronic diseases: An overview", International Journal of Pharmaceutical Sciences and Drug Research, 4(1), pp.10~14 (2012)
- Shah K, "Determination of sodium, potassium, calcium and lithium in a wheat grass by flame photometry", Pharma Science Monitor An International Journal of Pharmaceutical Sciences, pp.900~909 (2011)
- Ataollahi M, "The effect of wheat germ extract on premenstrual syndrome symptoms", Iranian journal of pharmaceutical research. IJPR, 14(1), pp.159~ (2015)
- Ozgoli G, "Essential oil of Citrus sinensis for the treatment of premenstrual syndrome; a randomized double-blind placebo-controlled trial", Journal of Reproduction & Infertility, 12(2) (2011)
- Tamborini A, "Value of standardized Ginkgo biloba extract (EGb 761) in the management of congestive symptoms of premenstrual syndrome", Revue francaise de gynecologie et d'obstetrique, 88(7- 9), pp.447~457 (1993)
- JS, B., "Novak's gynecology" (2012), golban publication
- Sugawara J, "Effect of endurance exercise training and curcumin intake on central arterial hemodynamics in postmenopausal women : pilot study", American journal of hypertension, 25(6), pp.651~656 (2012)
- Sabetkasaei M, "The study of the neuroprotective effects of curcumin, against homocysteine intracerebroventricular injection –induced cognition impairment and oxidative stress in the rat", Physiology and Pharmacology, 13(3), pp.328~339 (2009)
- Khayat S, "The effect of curcumin on premenstrual syndrome symptoms : a double-blind randomized clinical trial", Journal of Nursing and Midwifery Urmia University of Medical Sciences, 13(11), pp.935~944 (2016)
- Sharifi F, "Comparison of the effects of Matricaria chamomila(Chamomile)extract and mefenamic acid on the intensity of premenstrual syndrome", Complementary therapies in clinical practice, 20(1), pp.81~88 (2014)
- Heitmann K, "Safety of ginger use in pregnancy : results from a large population-based cohort study", European journal of clinical pharmacology, 69(2), pp.269~277 (2013)
- Baliga MS, "Update on the chemopreventive effects of ginger and its phytochemicals", Critical reviews in food science and nutrition, 51(6), pp.499~523 (2011)
- Khayat S, "Comparison the effects of Ginger and Curcumin in treatment of premenstrual syndrome", Iranian South Medical Journal(ISMJ), 18, pp.575~586 (2015)
- Salehi A, "The effect of Evening Primrose and Vitex on cyclic Mastalgia in comparison with vitamin E : a randomized clinical trial", Scientific Magazine Yafte, 15(2), pp.95~109 (2013)
- JAFARNEJAD F, "Comparison of the effect of fish oil and vitamin E on duration of cyclic mastalgia", Evidence Based Care, 3, pp.69~76 (2013)