본문 바로가기
KERD
논문KCI 등재

위의 간세포양 샘암종의 간전이 1예

A case of liver metastasis of gastric hepatoid adenocarcinoma

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

초록

간세포양 샘암종은 주로 알파태아단백을 생성하고 흔하게 발견되지는 않지만 진행암 상태로 많이 발견되며 림프절과 간으로 전이를 잘 하여 예후가 나쁜 특징을 보인다. 저자들은 다발성 간전이를 동반한 Borrmann III형의 진행성 간세포양 위샘암종을 위와 간병변의 조직검사 및 면역조직화학염색을 통해 진단한 사례를 경험하였기에 보고하는 바이다.

Abstract

We report herein a case of hepatoid adenocarcinoma of the stomach with liver metastasis. Gastric carcinoma generally presents as adenocarcinoma and rarely shows a hepatoid pattern, which can produce alpha- fetoprotein (AFP). The stomach is one of the common sites at which hepatoid adenocarcinoma has been detected. A 75-year-old female patient was admitted to the hospital with a symptom of epigastric discomfort. Gastrofibroscopy revealed a large tumor occupying the greater curvature of the stomach body. The level of serum AFP was markedly increased. Abdominal computed tomography revealed multiple liver masses. Biopsy samples of the gastric lesion and liver masses finally confirmed her case as hepatoid adenocarcinoma in the stomach with liver metastasis. The AFP-producing gastric carcinoma needs special attention because it often presents with early liver metastasis and has a poor prognosis.

참고문헌 (15)

  1. Bourreille J, "Existence of alpha-feto protein during gastric-origin secondary cancer of the liver", Presse Med, 78, pp.1277~1278 (1970)
  2. Ishikura H, "An AFP- producing gastric carcinoma with features of hepatic differentiation. A case report", Cancer, 56, pp.840~848 (1985)
  3. McIntire KR, "Serum alpha-fetoprotein in patients with neoplasm of the gastrointestinal tract", Cancer Res, 35, pp.991~996 (1975)
  4. Chang YC, "Alpha-fetoprotein producing early gastric cancer with liver metastasis: report of three cases", Gut, 32, pp.542~545 (1991)
  5. Kang GH, "Hepatoid adenocarcinoma of the stomach: a pathologic analysis of 14 cases", Korean J Pathol, 28, pp.620~628 (1994)
  6. Jun JD, "A study on the validity of serum alpha-fetoprotein for the screening of hepatocellular carcinoma among Korean adults", J Korean Acad Fam Med, 20, pp.1209~1215 (1999)
  7. Chun JB, "Hepatoid adenocarcinoma of the stomach", Korean J Med, 39, pp.554~562 (1990)
  8. Lee WJ, "A case of hepatioid adenocarcinoma of the stomach", Korean J Gastroenterol, 29, pp.129~133 (1997)
  9. 권우일, "간 전이를 동반한 위의 간양 선암 1예", 대한위암학회지, 5(2), pp.127~132 (2005), 대한위암학회
  10. Adachi Y, "AFP-producing gastric carcinoma: multivariate analysis of prognostic factors in 270 patients", Oncology, 65, pp.95~101 (2003)
  11. Aizawa K, "Different characteristics of hepatoid and non-hepatoid alpha-fetoprotein producing gastric carcinomas: an experimental study using xenografted tumors", Int J Cancer, 58, pp.430~435 (1994)
  12. Inagawa S, "Hepatoid adenocarcinoma of the stomach", Gastric Cancer, 4, pp.43~52 (2001)
  13. Terracciano LM, "Hepatoid adenocarcinoma with liver metastasis mimicking hepatocellular carcinoma: an immunohistochemical and molecular study of eight cases", Am J Surg Pathol, 27, pp.1302~1312 (2003)
  14. Hatta W, "A case of curatively resected AFP producing gastric cancer that responded remarkably to 1 course of TS-1 and showed complete loss of multiple liver metastatic tumors", Gan To Kagaku Ryoho, 32, pp.855~858 (2005)
  15. Chiba N, "AFP-producing hepatoid adenocarcinoma in association with Barrett's esophagus with multiple liver metastasis responding to paclitaxel", CDDP: a case report, 2005, pp.25, 2965~2968

관련 논문AI추천

이 간행물의 다른 논문 (8건)