난소에 전이된 원발성 간세포암 1예
A case of hepatocellular carcinoma with ovarian metastasis
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초록
원발성 간세포암이 난소에 전이하는 경우는 드물다. 이에 저자들은 간세포암 진단을 받고 경간동맥 항암화학 색전술 및 고주파 열치료를 시행받았던 환자에서 간내에 간세포암의 재발을 보이지는 않았으나 지속적인 알파태아단백 상승이 있던 중 난소에서 발견된 전이성 간세포암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Primary hepatocellular carcinoma with metastasis to the ovary is a rare malady. To the best of our knowledge, approximately eight cases in the English literature and two cases in the Korean literature have been reported. We report here a case of hepatocellular carcinoma with metastasis to the ovary in a 40-year-old woman who presented with a month long history of lower abdominal discomfort and a palpable mass. She had been diagnosed with hepatocellular carcinoma (HCC) four years prior and subsequently underwent a several courses of transarterial chemoembolization and radio-frequency ablation. The patient had then been seen regularly and was generally well until 4 month ago, when the alpha fetoprotein (AFP) level began to rise to 425 ng/mL. After that time she had been seen and examined every month, however, the AFP level rose to 2,150 ng/mL without evidence of recurrence on the computed tomography (CT) scan of liver, the heapatic artery angiography, PET and so on. On admission, a pelvis MRI revealed mainly solid masses of both ovaries and multiple peritoneal and omental nodules. Transvaginal core biopsy was performed and the histologic examination of the specimen revealed metastatic hepatocellular carcinoma. We report here on one case of ovarian metastasis from hepatocellular carcinoma together with a brief review of the literature.(Korean J Med 71:573-576, 2006)
참고문헌 (17)
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