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항호르몬요법을 받는 유방암 여성의 갱년기 증상과 연관 변인간의 분석

Menopausal Symptoms and Associated Factors in Breast Cancer Patients Receiving Hormone Therapy

김영란|민열하
병원간호사회 (Hospital Nurses Association)|2017.04|임상간호연구 (Journal of Korean Clinical Nursing Research)|제23권 제1호|pp. 120-129|DOI https://doi.org/10.22650/JKCNR.2017.23.1.120

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키워드

우울Depression유방암Breast NeoplasmsMenopause갱년기Medication Adherence복약 순응도호르몬요법Hormonal Antineoplastic Agents
주제분류간호학

초록

연구목적: 본 연구는 항호르몬요법을 받고 있는 유방암 환자를 대상으로 갱년기 증상의 정도와 연관된 변인을 확인하기 위함이다. 연구방법: 서울의 일개병원에 내원하여 항호르몬요법을 받고 있는 유방암 환자 150명을 대상으로 자료수집을 시행하였다. 대상자의 일반적, 임상적 및 심리적 특성에 따른 갱년기 증상의 정도를 비교하기 위해 t-test, ANOVA, 상관관계분석을 이용하였다. 연구결과: 갱년기 증상의 평균 점수는 13.39±7.97 이었다. 대상자 중 다수에서 갱년기의 신체화, 심리적, 비뇨생식계 증상 중 안면홍조와 발한(75.3%), 신체적ㆍ심리적 피로감(82.7%), 성적 문제(64.7%)를 갖는 것으로 나타났다. 우울은 모든 갱년기 증상과 연관되어 있었으며(p< .01) 신체화 증상은 연령, 폐경여부, 직업유무, 종양특성에서, 심리적 증상은 결혼상태, 수술유형, 항암화학요법 여부에서, 비뇨생식기계 증상은 암의 기왕력, 직업유무, 수술유형, 방사선요법여부에 따라 차이가 있었다. 결론: 본 연구결과는 갱년기 증상의 고위험군을 선별함으로써 항호르몬요법을 받는 유방암 환자들에게 증상에 따른 맞춤화된 간호 중재를 제공하는 데 활용될 수 있다.

Abstract

Purpose: The purpose of this study was to identify the degree of menopause symptoms and associated factors in patients with breast cancer who were receiving hormone therapy. Methods: Data were collected with questionnaires from 150 patients with breast cancer who had been on hormone therapy at a hospital in Seoul. Data were analyzed with the t-test, ANOVA, and Pearson correlation coefficient to compare the degree of menopause symptoms by demographic, clinical and psychological factors. Results: The mean menopause symptoms score was 13.39±7.97. Most participants reported having hot flushes and sweating (75.3%), physical and mental exhaustion (82.7%) and sexual problems (64.7%). Menopause symptoms and depression were correlated with each other (p<.01). Somato-vegetative symptoms were different significantly by age, menopausal status at time of operation, occupation and tumor. Psychological symptoms were different significantly by marital status, operation type and chemotherapy. Urogenital symptoms were different significantly by prior history of cancer, occupation, operation type and radiation therapy. Conclusion: These findings can be used to provide tailored nursing interventions by identifying high risk groups for menopausal symptom among breast cancer patients receiving hormone therapy

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