내분비요법 중인 폐경 전 유방암 환자의 디스트레스 영향 요인
Factors Influencing Distress in Premenopausal Patients with Breast Cancer Undergoing Endocrine Therapy
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연구목적: 본 연구는 수술 후 내분비요법 중인 폐경 전 유방암 환자의 갱년기 증상, 기능 상태 및 디스트레스 간의 관계와 디스트레스에 영향을 미치는 요인을 파악하기 위한 연구이다. 연구방법: 상급종합 병원에서 내분비요법 중인 유방암 환자 140명을 대상으로 설문지를 사용하여 자료를 수집하였다. 수집된 자료는 서술통계, t-test, ANOVA, Tukey HSD test, Pearson's correlation coefficients, 위계적 회귀분석으로 분석하였다. 연구결과: 대상자의 갱년기 증상, 기능 상태, 디스트레스의 평균 점수는 각각 19.65±7.86점, 2.67±0.33점, 3.69±2.19점이었다. 대상자의 갱년기 증상과 디스트레스는 통계적으로 유의한 양의 상관관계를 나타내었다(r=.76, p<.001). 갱년기 증상과 기능 상태(r=-.43, p<.001), 기능 상태와 디스트레스(r=-.31, p<.001)는 모두 통계적으로 유의한 음의 상관관계를 나타내었다. 디스트레스에 가장 큰 영향을 미치는 요인은 갱년기 증상이었다(β= .79, p<.001). 결론: 본 연구 결과를 바탕으로 갱년기 증상과 디스트레스 감소에 초점을 맞춘 간호 중재 프로그램 개발을 제언한다.
Abstract
Purpose: The purpose of this study was to investigate relationships among menopausal symptoms, functional status, and distress and to identify factors influencing distress in premenopausal breast cancer patients who had been on endocrine therapy. Methods: A descriptive correlational study was conducted. Data were collected using questionnaires from 140 patients with breast cancer undergoing endocrine therapy at a general hospital. Data were analyzed using descriptive statistics, t-test, ANOVA, Tukey HSD test, Pearson’s correlation analysis and hierarchical regression analysis. Results: The mean scores for menopausal symptom, functional status, and distress were 19.65±7.86, 2.67±0.33 and 3.69±2.19, respectively. The menopausal symptoms and distress were positively correlated (r=.76, p<.001). The menopausal symptoms and functional status (r=-.43, p<.001) and functional status and distress (r=-.31, p<.001) were negatively correlated. The most influential factor for distress was menopausal symptoms (β=.79, p<.001). Conclusion: Based on the findings of this study, developing nursing intervention programs focusing on decreasing menopausal symptoms and distress are recommended.
참고문헌 (30)
- "Cancer statistics 2017" (2017)[URL]
- "Breast cancer facts & figures 2017" (2017)[URL]
- Korean Breast Cancer Society, "The breast" (2017), Korean Breast Cancer Society
- Harold J. Burstein, "Adjuvant Endocrine Therapy for Women With Hormone Receptor–Positive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Focused Update", Journal of Clinical Oncology, 32(21), pp.2255~2269 (2014), American Society of Clinical Oncology (ASCO)[DOI]
- 김영란, "항호르몬요법을 받는 유방암 여성의 갱년기 증상과 연관 변인간의 분석", 임상간호연구, 23(1), pp.120~129 (2017), 병원간호사회[DOI]
- 황은경, "항호르몬요법을 받는 유방암 환자의 삶의 질 영향 요인", Journal of Korean Academy of Nursing, 44(1), pp.108~117 (2014), 한국간호과학회
- S. M. Rosenberg, "Symptoms and Symptom Attribution Among Women on Endocrine Therapy for Breast Cancer", The Oncologist, 20(6), pp.598~604 (2015), Alphamed Press[DOI]
- Tsogzolmaa Dorjgochoo, "Menopausal symptoms among breast cancer patients 6 months after diagnosis", Menopause, 16(6), pp.1205~1212 (2009), Ovid Technologies (Wolters Kluwer Health)[DOI]
- Tulman L, "Development of the inventory of functional status cancer", Cancer Nursing, 14(5), pp.254~260 (1991)
- Sevgi Ozkan, "Psychometric Analysis of the Inventory of Functional Status—Cancer (IFS-CA) in Turkish Women", Journal of Transcultural Nursing, 20(2), pp.187~193 (2008), SAGE Publications[DOI]
- Kimmick GG, "Randomized, double-blind, placebo-controlled, crossover study of sertraline(Zoloft)for the treatment of hot flushes in women with early stage breast cancer taking tamoxifen", The Breast Journal, 12(2), pp.114~122 (2006)
- D.U. BOEHM, "Quality of life and adjuvant tamoxifen treatment in breast cancer patients", European Journal of Cancer Care, 18(5), pp.500~506 (2009), Wiley[DOI]
- "NCCN Guidelines & Clinical Resources: NCCN Guidelines for Supportive Care:Distress management" (2017)[URL]
- Simone S.M. Ho, "Anxiety, depression and quality of life in Chinese women with breast cancer during and after treatment: A comparative evaluation", European Journal of Oncology Nursing, 17(6), pp.877~882 (2013), Elsevier BV[DOI]
- 조한철, "추적 기간에 따른 유방암 생존자들의 디스트레스와 삶의 질", Journal of Breast Disease, 4(2), pp.58~63 (2016), 한국유방암학회[DOI]
- L. Jørgensen, "Prevalence and predictors of distress in women taking part in surgical continuity of care for breast cancer: A cohort study", European Journal of Oncology Nursing, 22, pp.30~36 (2016), Elsevier BV[DOI]
- Birgitte Goldschmidt Mertz, "Psychological distress among women with newly diagnosed breast cancer", European Journal of Oncology Nursing, 16(4), pp.439~443 (2012), Elsevier BV[DOI]
- 권은진, "한국 유방암 생존자들의 디스트레스와 삶의 질", Asian Oncology Nursing, 12(4), pp.289~296 (2012), 대한종양간호학회[DOI]
- 서지영, "항암화학요법을 받는 암 환자의 디스트레스와 삶의 질", Asian Oncology Nursing, 15(1), pp.18~27 (2015), 대한종양간호학회
- Patricia A. Ganz, "Impact of Adjuvant Endocrine Therapy on Quality of Life and Symptoms: Observational Data Over 12 Months From the Mind-Body Study", Journal of Clinical Oncology, 34(8), pp.816~824 (2016), American Society of Clinical Oncology (ASCO)[DOI]
- Mariana S. Sousa, "A clinical guide to the management of genitourinary symptoms in breast cancer survivors on endocrine therapy", Therapeutic Advances in Medical Oncology, 9(4), pp.269~285 (2017), SAGE Publications[DOI]
- Jo Marsden, "The menopause specialist and breast cancer survivorship", Post Reproductive Health, 22(4), pp.147~154 (2016), SAGE Publications[DOI]
- Jun J. Mao, "Patterns and risk factors associated with aromatase inhibitor-related arthralgia among breast cancer survivors", Cancer, 115(16), pp.3631~3639 (2009), Wiley[DOI]
- Young Ho Yun, "Development of a Cancer Pain Assessment Tool in Korea: A Validation Study of a Korean Version of the Brief Pain Inventory", Oncology, 66(6), pp.439~444 (2004), S. Karger AG[DOI]
- Heinemann LA, "International versions of the Menopause Rating Scale(MRS)", Health and Quality of Life Outcomes, 1, pp.28~ (2003)
- Suh EY, "The effects of rhythmic walking exercise on physical strength, fatigue, and functional status of breast cancer patients in adjuvant chemohterapy", Korean Journal of Adult Nursing, 9(3), pp.422~437 (1997)
- Hyojung Park, "Menopausal symptoms, sexual function, depression, and quality of life in Korean patients with breast cancer receiving chemotherapy", Supportive Care in Cancer, 21(9), pp.2499~2507 (2013), Springer Science and Business Media LLC[DOI]
- Paul A. Cohen, "Managing menopausal symptoms after breast cancer – A multidisciplinary approach", Maturitas, 105, pp.4~7 (2017), Elsevier BV[DOI]
- 서미혜, "유방암 생존자의 피로와 디스트레스가 자기효능감에 미치는 영향", 성인간호학회지, 28(4), pp.378~387 (2016), 한국성인간호학회[DOI]
- 박진희, "일차 치료종료 후 유방암환자의 디스트레스와 영향요인", Asian Oncology Nursing, 15(3), pp.132~139 (2015), 대한종양간호학회