본문 바로가기
KERD
논문KCI 등재후보

The relationship between left ventricular mass index and body composition in new-diagnosed hypertensive patients

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

Background: Cardiovascular disease (CVD) is considered a public health burden and most common cause of mortality in all over the world. The latency time for developing CVD may be several decades. the objective of this study was to examine the relationship between body composition and Left Ventriculare Mass Index (LVMI) in newly diognosed hypertensive patients. Methods: We enrolled 120 new-diagnosed hypertensive patients (mean age 45 ± 8 years) who admitted to our nephrology clinic. Body fat percentage (BFP) was measured by bioelectrical impedance (BIA). Echocardiography examinations were performed for all patients. Results: Mean values of Waist hip ratio, Body mass ındex, Body fat percentage, Systolic blood pressure, Diastolic blood pressure were significantly higher for females than males (all p values <0.05). The female patients had higher LVMI than male patients (94.8 ± 13.1 vs 89.2 ± 14.6, p < 0.05). The study patients were divided into 3 groups according to their BFP defined by BIA. Group 3 patients, who exhibited higher body fat, had significantly higher BMI (p < 0,05), total leukocyte count (p < 0.05), CRP (p < 0.05), triglyceride (p < 0.05), and female predominance. Group 3 patients were statistically older than group 1 patients (46.2 vs. 40.6 years, p < 0.05). Additionally, LVMI levels were higher in Group 3 than Group 1 (p < 0.05) (Table 3). In logistic regression analysis, independent factors affecting LVMI were age, weight, gender and BFP (all p values were <0.05). Conclusions: BFP was associated with higher LVMI, in newly diognosed hypertensive patients. Its use results in significantly lower proportions of individuals with LVH in the population, in particular among hypertensive and the obese patients.

Abstract

Background: Cardiovascular disease (CVD) is considered a public health burden and most common cause of mortality in all over the world. The latency time for developing CVD may be several decades. the objective of this study was to examine the relationship between body composition and Left Ventriculare Mass Index (LVMI) in newly diognosed hypertensive patients. Methods: We enrolled 120 new-diagnosed hypertensive patients (mean age 45 ± 8 years) who admitted to our nephrology clinic. Body fat percentage (BFP) was measured by bioelectrical impedance (BIA). Echocardiography examinations were performed for all patients. Results: Mean values of Waist hip ratio, Body mass ındex, Body fat percentage, Systolic blood pressure, Diastolic blood pressure were significantly higher for females than males (all p values <0.05). The female patients had higher LVMI than male patients (94.8 ± 13.1 vs 89.2 ± 14.6, p < 0.05). The study patients were divided into 3 groups according to their BFP defined by BIA. Group 3 patients, who exhibited higher body fat, had significantly higher BMI (p < 0,05), total leukocyte count (p < 0.05), CRP (p < 0.05), triglyceride (p < 0.05), and female predominance. Group 3 patients were statistically older than group 1 patients (46.2 vs. 40.6 years, p < 0.05). Additionally, LVMI levels were higher in Group 3 than Group 1 (p < 0.05) (Table 3). In logistic regression analysis, independent factors affecting LVMI were age, weight, gender and BFP (all p values were <0.05). Conclusions: BFP was associated with higher LVMI, in newly diognosed hypertensive patients. Its use results in significantly lower proportions of individuals with LVH in the population, in particular among hypertensive and the obese patients.

참고문헌 (26)

  1. Lozano R., "Global and regional mortality from 235 causes of death for 20 age groups in 1990and 2010 : a systematic analysis for the Global Burden of Disease Study 2010", The Lancet, 380(9859), pp.2095~2128 (2013)
  2. Liao Y., "Left ventricular hypertrophy has a greater impact on survival in women than in men", Circulation, 92, pp.805~810 (1995)
  3. Cassidy AE., "Progression of subclinical coronary atherosclerosis : does obesity make a difference?", Circulation, 111, pp.1877~1882 (2005)
  4. Fantuzzi G., "Adipose tissue, adipokines, and inflammation", J Allergy CLin Immunol, 115, pp.911~919 (2005)
  5. Liao Y., "Prediction of mortality risk by different methods of indexation for left ventricular mass", J Am Coll Cardiol, 26, pp.641~647 (1997)
  6. Abergel E., "Which definition for echocardiographic left ventricular hypertrophy?", Am J Cardiol, 75, pp.498~502 (1995)
  7. Daniels SR., "Indexing left ventricular mass to account for differences in body size in children and adolescents without cardiovascular disease", J Am Coll Cardiol, 76, pp.699~701 (1995)
  8. Hense HW., "The associations of body size and body composition with left ventricular mass : impacts for indexation in adults", J Am Coll Cardiol, 32, pp.451~457 (1998)
  9. Kushner R., "Bioelectrical impedance analysis : a review of principles and applications", J Am Coll Nutr, 11, pp.199~209 (1992)
  10. Fuller NJ., "Comparison of abilities of various interpretations of bioelectrical impedance to predict reference method body composition assessment", Clin Nutr, 12, pp.236~242 (1993)
  11. Devereux RB., "Echocardiographic assessment of left ventricular hypertrophy : Comparison to necropsy findings", J Am Coll Cardiol, 57, pp.450~458 (1986)
  12. Ntaios G., "Adipokines as mediators of endothelial function and atherosclerosis", Atherosclerosis, 227, pp.216~221 (2013)
  13. Matsuzawa Y., "Adiponectin : Identification, physiology and clinical relevance in metabolic and vascular disease", Atheroscler Suppl, 6, pp.7~14 (2005)
  14. Lunenfeld B., "Endocrinology of ageing male", Minerva Ginecol, 58, pp.153~170 (2006)
  15. Huang CX., "Both low muscle mass and low fat are associated with higher all-cause mortality", Kidney Int, 77, pp.624~629 (2010)
  16. Oterdoom LH., "Urinary creatinine excretion, an indirect measure of muscle mass, is an independent predictor of cardiovascular disease and mortality in the general population", Atherosclerosis, 207, pp.534~540 (2009)
  17. Sezer S., "Body fat percentage as a risk factor for atherosclerosis but not for inflammation for hemodialysis patients : differences between genders", J Ren Nutr, 22(5), pp.490~498 (2012)
  18. Chandie Shaw PK., "Central obesity is an independent risk factor for albuminuria in nondiabetic South Asian subjects", Diabetes Care, 30, pp.1840~1844 (2007)
  19. Feldstein CA., "A comparison of body mass index and waist-to-hip ratio as indicators of hypertension risk in an urban Argentine population : a hospital-based study", Nutr Metab Cardiovasc Dis, 15, pp.310~315 (2005)
  20. Gustavson B., "Adipose tissue, inflammation and atherosclerosis", J Atheroscler Thromb, 17, pp.332~341 (2010)
  21. Turk JR., "C-reactive protein correlates with macrophage accumulation in coronary arteries of hypercholesterolemic pigs", J Appl Physiol, 95, pp.1301~1304 (2003)
  22. Axelsson J., "Adipose tissue and its relation to inflammation : the role of adipokines", J Ren Nutr, 15, pp.131~136 (2005)
  23. Barbieri A., "Left ventricular hypertrophy reclassification and death : application of the Recommendation of the American Society of Echocardiography", European Association of Echocardiography, 2012, pp.13, 109~117
  24. Wajchenberg BL., "Subcutaneous and visceral adipose tissue : Their relation to the metabolic syndrome", Endocr Rev, 21, pp.697~738 (2000)
  25. Barzi F., "The discrimination of dyslipidaemia using anthropometric measures in ethnically diverse populations of the Asia-Pacific Region : theObesity in Asia Collaboration", Obes Rev, 11, pp.127~136 (2010)
  26. Campese VM., "Abnormal renal hemodynamics in black salt-sensitive patients with hypertension", Hypertension, 18, pp.805~812 (1991)

관련 논문AI추천

Epicardial Fat Thickness and Neutrophil to Lymphocyte Ratio are Increased in Non-Dipper Hypertensive Patients김봉준, 김현수, 박동현, 유가인, 임성일, 조경임, 차태준, 최지훈, 허정호한국심초음파학회 · Journal of Cardiovascular Imaging2016 · 제24권 제4호The Association of Left Ventricular Hypertrophy with Intraventricular Dyssynchrony at Rest and during Exercise in Hypertensive Patients서존, 서혜선, 이내희, 임오경, 조윤행, 최재혁한국심초음파학회 · Journal of Cardiovascular Imaging2012 · 제20권 제4호Clinical Characteristics Associated with Electrocardiographic Left Ventricular Hypertrophy in Clinical Normotensives without a History of Hypertension: a Cross-Sectional Study노혜미, 박경희, 백유진, 서영균, 송홍지, Geonhyeok Kim, Hyoeun Lee대한가정의학회 · Korean Journal of Family Medicine2019 · 제40권 제2호일개 농촌 인구 집단에서 고혈압과 비만이 심초음파로 측정한 좌심실비대 및 미세단백뇨에 미치는 영향김미경, 김배근, 김유미, 신진호, 최보율, 한상웅대한고혈압학회 · Clinical Hypertension2011 · 제17권 제4호여성 고혈압 환자에서 부적절한 좌심실비대와 Framingham Risk Score 및 혈관경직도와의 관계김지혜, 김혜미, 이학승, 정지현, 조구영대한고혈압학회 · Clinical Hypertension2013 · 제19권 제3호정상 혈압 성인에서 비만도와 좌심실 질량과의 관계김종성, 박웅섭, 신윤정, 양선우, 오미경, 유동식, 이두영, 정상식, 최은진대한가정의학회 · Korean Journal of Family Medicine2007 · 제28권 제4호