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운동이 기분 및 우울증에 미치는 영향 및 임상적 적용 : 신경가소성의 관점에서

Beneficial Effects of Exercise on Mood and Depression and Clinical Application : in the Scope of Neuroplasticity

김병수|민유선
대한생물치료정신의학회 (Korean Society Of Biological Therapies In Psychiatry)|2017.10|생물치료정신의학 (Journal of the Korean Society of Biological Therapies in Psychiatry)|제23권 제3호|pp. 138-146|DOI 10.22802/jksbtp.2017.23.3.138

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키워드

우울증·기분장애·운동·신경가소성.Depression · Mood disorders · Exercise · Neuronal plasticity.
주제분류정신과학

초록

Exercise is an effective treatment for depression and can be applied in an additional way to pharmacotherapy. From the scope of neuroplasticity, it is closely related to the adult neurogenesis of the hippocampus. Factors mediating this include BDNF, VEGF, IGF-1, serotonin, and anandamide. Observational studies have shown that active people are less likely to suffer from depression, and interventional studies have shown that exercise helps to reduce depression. Exercise may have an additional effect in mild and moderate depression patients, and it may be helpful to prescribe aerobic exercise and strength training together. Monitoring the intensity of exercise using an objective method of heart rate or subjective perceived exertional scale to maintain moderate intensity may lead to optimal exercise in depressed patients.

Abstract

Exercise is an effective treatment for depression and can be applied in an additional way to pharmacotherapy. From the scope of neuroplasticity, it is closely related to the adult neurogenesis of the hippocampus. Factors mediating this include BDNF, VEGF, IGF-1, serotonin, and anandamide. Observational studies have shown that active people are less likely to suffer from depression, and interventional studies have shown that exercise helps to reduce depression. Exercise may have an additional effect in mild and moderate depression patients, and it may be helpful to prescribe aerobic exercise and strength training together. Monitoring the intensity of exercise using an objective method of heart rate or subjective perceived exertional scale to maintain moderate intensity may lead to optimal exercise in depressed patients.

참고문헌 (76)

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