본문 바로가기
KERD
논문KCI 등재

자궁근종을 동반한 난임 여성의 한의학적 치료에 대한 연구 동향

A Review on Research of Korean Medicine Treatments for Infertile Women with Uterine Myoma

이진무|장준복|최민영|이창훈|황덕상|고은빈|박남경
대한한방부인과학회 (The Society Of Oriental Obstetrics & Gynecology)|2023.08|대한한방부인과학회지 (The Journal of Oriental Obstetrics ＆ Gynecology)|제36권 제3호|pp. 196-210

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

Research TrendsKorean MedicineInfertilitySubfertilityUterine MyomaLeiomyoma
주제분류한의학

초록

Objectives: The purpose of this study is to review the research trends of infertile women with uterine myoma in Korean medicine and to recognize the efficacy of Korean medicine intervention. Methods: A search was conducted on November 18, 2022, using six databases, including Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Cochrane Library Central, Pubmed, China National Knowledge Infrastructure (CNKI) and WangFang Med Online. We analyzed the studies using Korean medicine on women with uterine myoma preparing for pregnancy or complaining infertility. Results: Total 4 studies were selected and all of which were case reports. Among 6 cases, Korean medicine treatment including herbal medicine, acupuncture, electroacupuncture, moxibustion was used alone. Ikgibohyeol-tang-gami-bang, Gyejibokryeong-hwan, Saenghwa-tang-gami-bang were prescribed in 2 cases each. Angelicae Gigantis Radix and CV4 were most frequently used herb and acupoint. All subjects were successful in becoming pregnant. Conclusion: This review shows that Korean medicine treatment can be effective in infertile women with uterine myoma. However, the number of included studies is small, so the level of evidence needs to be raised through more clinical studies in the future.

Abstract

Objectives: The purpose of this study is to review the research trends of infertile women with uterine myoma in Korean medicine and to recognize the efficacy of Korean medicine intervention. Methods: A search was conducted on November 18, 2022, using six databases, including Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Cochrane Library Central, Pubmed, China National Knowledge Infrastructure (CNKI) and WangFang Med Online. We analyzed the studies using Korean medicine on women with uterine myoma preparing for pregnancy or complaining infertility. Results: Total 4 studies were selected and all of which were case reports. Among 6 cases, Korean medicine treatment including herbal medicine, acupuncture, electroacupuncture, moxibustion was used alone. Ikgibohyeol-tang-gami-bang, Gyejibokryeong-hwan, Saenghwa-tang-gami-bang were prescribed in 2 cases each. Angelicae Gigantis Radix and CV4 were most frequently used herb and acupoint. All subjects were successful in becoming pregnant. Conclusion: This review shows that Korean medicine treatment can be effective in infertile women with uterine myoma. However, the number of included studies is small, so the level of evidence needs to be raised through more clinical studies in the future.

참고문헌 (38)

  1. Korean Society of Obstetrics and Gynecology, "Gynecology", pp.515~516 (2021), Koonja
  2. 난임의 임상적 원인과지원 방안에 대한 제안 연구, "Jung JE", NHIS Ilsan Hospital Institute of Health Insurance & Clinical Research, ~ (2017)
  3. 김용만, "자궁근종의 치료: 어떤 방법을 선택할 것인가?", 대한의사협회지, 58(12), pp.1147~1153 (2015), 대한의사협회[DOI]
  4. Wallach EE, "Uterine myomas : an overview of development, clinical features, and management", Obstet Gynecol, 104(2), pp.393~406 (2004)
  5. 김재덕, "불임 여성에서 복식 자궁근종절제술 후 임신에 미치는 인자에 관한 연구", Obstetrics & Gynecology Science, 46(3), pp.9~9 (2003), 대한산부인과학회
  6. Rosenfeld DL, "Abdominal myomectomy for otherwise unexplained infertility", Fertil Steril, 46(2), pp.328~330 (1986)
  7. Klatsky PC, "Fibroids and reproductive outcomes : a systematic literature review from conception to delivery", Am J Obstet Gynecol, 198(4), pp.357~366 (2008)
  8. Milazzo GN, "Myoma and myomectomy : poor evidence concern in pregnancy", J Obstet Gynaecol Res, 43(12), pp.1789~1804 (2017)
  9. The Society of Korean Medicine Obstetrics and Gynecology, "Korean medicine Obstetrics & Gyenecology. Vol 2", pp.50~ (2021), Euiseongdang
  10. 소민지, "국내에서 수행된 난임 관련 한의학 치료 임상연구 경향 고찰", 대한한방부인과학회지, 30(1), pp.42~55 (2017), 대한한방부인과학회[DOI]
  11. 이희재, "玄胡索이 자궁근종세포의 증식억제와 Apoptosis 관련 유전자 발현에 미치는 영향", 대한한방부인과학회지, 19(2), pp.214~225 (2006), 대한한방부인과학회
  12. 이수진, "益母草가 자궁근종세포의 증식억제와 Apoptosis 관련 유전자 발현에 미치는 영향", 대한한방부인과학회지, 19(3), pp.1~12 (2006), 대한한방부인과학회
  13. 엄윤경, "자궁근종의 치료효과에 관한 임상적 연구", 동의생리병리학회지, 20(4), pp.1073~1077 (2006), 한의병리학회
  14. 최유진, "자궁근종의 한약치료에 대한 최신 임상 연구 동향 -CNKI 검색을 중심으로", 대한한방부인과학회지, 33(2), pp.13~28 (2020), 대한한방부인과학회[DOI]
  15. 장세란, "임신을 위해 단기간 한방치료 받은 자궁근종 환자 3례", 대한한방부인과학회지, 25(3), pp.157~167 (2012), 대한한방부인과학회[DOI]
  16. 조성희, "자궁근종, 자궁선근증을 동반한 여성 불임환자 1례의 임상보고", 동의생리병리학회지, 28(3), pp.355~358 (2014), 한의병리학회
  17. 이정임, "자궁근종 및 자궁선근증을 동반한 불임환자 증례보고", 대한한방부인과학회지, 28(1), pp.158~166 (2015), 대한한방부인과학회
  18. Teng B, "Successful Pregnancy after Treatment with Chinese Herbal Medicine in a 43-Year-Old Woman with Diminished Ovarian Reserve and Multiple Uterus Fibrosis : A Case Report", Medicines, 4(1), pp.7~ (2017)
  19. Elder-Geva T, "Effect of intramural, subserosal, and submucosal uterine fibroids on the outcome of assisted reproductive technology treatment", Fertil Steril, 70(4), pp.687~691 (1998)
  20. Pritts EA, "Fibroids and infertility : an updated systematic review of the evidence", Fertil Steril, 91(4), pp.1215~1223 (2009)
  21. Roger Hart, "A prospective controlled study of the effect of intramural uterine fibroids on the outcome of assisted conception", Hum Reprod, 16(11), pp.2411~2417 (2001)
  22. Check JH, "The effect on IVF outcome of small intramural fibroids not compressing the uterine cavity as determined by a prospective matched control study", Hum Reprod, 17(5), pp.1244~1248 (2002)
  23. 이애현, "근층내 자궁근종이 체외수정시술의 결과에 미치는 영향", Obstetrics & Gynecology Science, 47(5), pp.957~965 (2004), 대한산부인과학회
  24. ACOG Committee on Practice Bulletins, "Alternatives to Hysterectomy in the Management of Leiomyomas", American College of Obstetricians and Gynecologists, 96, pp.1~14 (2008)
  25. Goldberg J, "Pregnancy outcomes after treatment for fibromyomata : uterine artery embolization versus laparoscopic myomectomy", Am J Obstet Gynecol, 191(1), pp.18~21 (2004)
  26. Wu G, "A comparison of the pregnancy outcomes between ultrasound-guided highintensity focused ultrasound ablation and laparoscopic myomectomy for uterine fibroids : a comparative study", Int J Hyperthermia, 37(1), pp.617~623 (2020)
  27. Kim SR, "Fertility Issues on Patients with Myoma", Korean J Reprod Med, 37(3), pp.191~198 (2010)
  28. 엄지수, "가임기 여성의 자궁근종의 보존적 치료와 임신 예후", 한국모자보건학회지, 26(2), pp.45~51 (2022), 한국모자보건학회
  29. "Mean age of mother at first birth"[URL]
  30. Lee SJ, "Nationwide population-based cohort study of adverse obstetric outcomes in pregnancies with myoma or following myomectomy : retrospective cohort study", BMC Pregnancy Childbirth, 20(1), pp.716~ (2020)
  31. Heo J., "Dongeuibogam", pp.1781~1782 (2010), Dongeuibogam publishing company
  32. "Northern Pharmacy", 2019, 133~134
  33. Kim JH, "Literature Review on Biological Effects of Gyejibokryeonghwan against Gynaecological Diseases", J Korean Med, 34(2), pp.29~40 (2013)
  34. Miura S, "Differential infiltration of macrophages and prostaglandin production by different uterine leiomyomas", Hum Reprod, 21(10), pp.2545~2554 (2006)
  35. Li JM, "Regulation effect and mechanism of Sheng-Hua-Tang on female reproductive system : From experimental transcriptomic analysis to clinical applications", J Ethnopharmacol, 249, pp.112431~ (2020)
  36. Xi J, "Electroacupuncture Improves Pregnancy Outcomes in Rats with Thin Endometrium by Promoting the Expression of Pinopode-Related Molecules", BioMed Research International, 2021, pp.6658321~ (2021)
  37. Li X, "Regulation of Mild Moxibustion on Uterine Vascular and Prostaglandin Contents in Primary Dysmenorrhea Rat Model", Evidence-Based Complementary and Alternative Medicine, 2021, pp.9949642~ (2021)
  38. "최근 5년(2017~2021년)동안자궁근종 환자수 크게 증가"[URL]

관련 논문AI추천

자궁근종의 한의학적 치료에 대한 국내 임상 논문 분석박준영, 이주현대한한방부인과학회 · 대한한방부인과학회지2024 · 제37권 제4호자궁근종, 자궁선근증을 동반한 여성 불임환자 1례의 임상보고조성희, 최찬헌한의병리학회 · 동의생리병리학회지2014 · 제28권 제3호임신을 위해 단기간 한방치료 받은 자궁근종 환자 3례김동철, 박영선, 장세란대한한방부인과학회 · 대한한방부인과학회지2012 · 제25권 제3호자궁근종의 한약치료에 대한 최신 임상 연구 동향 -CNKI 검색을 중심으로김보리, 양승정, 조성희, 최유진대한한방부인과학회 · 대한한방부인과학회지2020 · 제33권 제2호초음파를 이용하여 관찰한 자궁근종의 한의 치료 경과 고찰 2례 : 증례보고박웅, 곽유진, 박상희, 박성우, 정명주, 조희근대한한방부인과학회 · 대한한방부인과학회지2015 · 제28권 제1호자궁샘근증의 한의학적 치료에 대한 국내 연구 동향 고찰김노현, 도호정, 문혜연, 서창용, 소민지, 송현섭, 신재권, 이성엽, 이윤재대한한방부인과학회 · 대한한방부인과학회지2017 · 제30권 제4호

이 간행물의 다른 논문 (11건)

보음전의 항산화, 항염증 효능에 관한 실험연구조성희, 양승정, 김수경pp. 1-24난소 낭종의 한의학적 치료에 대한 국내 임상연구 동향 분석이창훈, 황덕상, 최정윤, 이진무, 장준복pp. 25-45여성 만성 변비의 침 치료 효과에 대한 체계적 문헌 고찰황덕상, 이진무, 장준복, 이창훈, 김수정, 이시원pp. 46-61습관성 유산의 한의학적 치료에 대한 국내 임상 연구 고찰김형준, 강소현, 권한슬pp. 62-77만성 골반 염증성 질환의 계지복령환 및 계지복령환 가감방 투여에 대한 중의학 연구 동향 : 무작위 대조군 임상 연구를 중심으로이희윤, 정연수, 윤영진, 박장경pp. 78-94
원문 보기