Contrast-enhanced Magnetic Resonance Imaging of Brain Metastases at 7.0T versus 1.5T: A Preliminary Result
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: To compare the depiction of brain metastases on contrast-enhanced imageswith 7.0 tesla (T) and at 1.5T MRI. Materials and Methods: Four consecutive patients with brain metastases werescanned on 7.0T whole-body scanner and 1.5T MRI. A 3D T1-weighted gradient echosequence (3D T1-GRE) at 1.5T (voxel size = 0.9 × 0.9 × 1.5 mm3 after double-dose,gadoterate meglumine, Gd-DOTA) was compared to a 7.0T 3D T1-GRE sequence(voxel size = 0.4 × 0.4 × 0.8 mm3, single-dose Gd-DOTA) in four patients after a 5minute delay. The number of contrast-enhancing metastases in MPRAGE images wascompared in each patient by two radiologists in consensus. We measured contrastratio of enhancing brain metastases and white matter in 1.5T and 7.0T. Results: In all four patients 7.0T 3D T1-GRE images after single-dose Gd-DOTAand 1.5T after double-dose Gd-DOTA depicted 11 brain metastases equally. In thequantitative analysis of contrast ratios of enhancing brain metastases and whitematter, the 1.5T 3D T1-GRE after double-dose showed an increased contrast ratiocompared to 7.0T 3D T1-GRE after single-dose (0.961 ± 0.571 versus 0.885 ± 0.494; n= 11 metastases). But this difference was not statistically significant (P = 0.711). Conclusion: Our preliminary results indicate that 7.0T single-dose Gd-enhancedimages were not different to 1.5T double-dose Gd-enhanced images for the detectionof brain metastases.
Abstract
Purpose: To compare the depiction of brain metastases on contrast-enhanced imageswith 7.0 tesla (T) and at 1.5T MRI. Materials and Methods: Four consecutive patients with brain metastases werescanned on 7.0T whole-body scanner and 1.5T MRI. A 3D T1-weighted gradient echosequence (3D T1-GRE) at 1.5T (voxel size = 0.9 × 0.9 × 1.5 mm3 after double-dose,gadoterate meglumine, Gd-DOTA) was compared to a 7.0T 3D T1-GRE sequence(voxel size = 0.4 × 0.4 × 0.8 mm3, single-dose Gd-DOTA) in four patients after a 5minute delay. The number of contrast-enhancing metastases in MPRAGE images wascompared in each patient by two radiologists in consensus. We measured contrastratio of enhancing brain metastases and white matter in 1.5T and 7.0T. Results: In all four patients 7.0T 3D T1-GRE images after single-dose Gd-DOTAand 1.5T after double-dose Gd-DOTA depicted 11 brain metastases equally. In thequantitative analysis of contrast ratios of enhancing brain metastases and whitematter, the 1.5T 3D T1-GRE after double-dose showed an increased contrast ratiocompared to 7.0T 3D T1-GRE after single-dose (0.961 ± 0.571 versus 0.885 ± 0.494; n= 11 metastases). But this difference was not statistically significant (P = 0.711). Conclusion: Our preliminary results indicate that 7.0T single-dose Gd-enhancedimages were not different to 1.5T double-dose Gd-enhanced images for the detectionof brain metastases.
참고문헌 (29)
- Klos KJ, "Brain metastases", Neurologist, 10, pp.31~46 (2004)
- Arnold SM, "Diagnosis and management of brain metastases", Hematol Oncol Clin North Am, 15(vii), pp.1085~1107 (2001)
- Sanchez de Cos J, "Non-small cell lung cancer and silent brain metastasis. Survival and prognostic factors", Lung Cancer, 63, pp.140~145 (2009)
- Smalley SR, "Adjuvant radiation therapy after surgical resection of solitary brain metastasis: association with pattern of failure and survival", Int J Radiat Oncol Biol Phys, 13, pp.1611~1616 (1987)
- Davis PC, "Diagnosis of cerebral metastases: double-dose delayed CT vs contrast-enhanced MR imaging", AJNR Am J Neuroradiol, 12, pp.293~300 (1991)
- Engh JA, "Optimizing intracranial metastasis detection for stereotactic radiosurgery", Stereotact Funct Neurosurg, 85, pp.162~168 (2007)
- Jena A, "Magnetic resonance (MR) patterns of brain metastasis in lung cancer patients: correlation of imaging findings with symptom", J Thorac Oncol, 3, pp.140~144 (2008)
- Runge VM, "High-dose gadoteridol in MR imaging of intracranial neoplasms", J Magn Reson Imaging, 2, pp.9~18 (1992)
- Sze G, "Comparison of singleand triple-dose contrast material in the MR screening of brain metastases", AJNR Am J Neuroradiol, 19, pp.821~828 (1998)
- Hawighorst H, "Contrastenhanced magnetization transfer imaging: improvement of brain tumor conspicuity and delineation for radiosurgical target volume definition", Radiother Oncol, 43, pp.261~267 (1997)
- Komada T, "Contrast-enhanced MR imaging of metastatic brain tumor at 3 tesla: utility of T(1)-weighted SPACE compared with 2D spin echo and 3D gradient echo sequence", Magn Reson Med Sci, 7, pp.13~21 (2008)
- Trattnig S, "The optimal use of contrast agents at high field MRI", Eur Radiol, 16, pp.1280~1287 (2006)
- 백선하, "Clinical Application of 7.0 T Magnetic Resonance Images in Gamma Knife Radiosurgery for a Patient with Brain Metastases", Journal of Korean Medical Science, 26(6), pp.839~843 (2011), 대한의학회
- Yuh WT, "Clinical magnetic resonance imaging of brain tumors at ultrahigh field: a state-of-the-art review", Top Magn Reson Imaging, 17, pp.53~61 (2006)
- Nobauer-Huhmann IM, "Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla", Invest Radiol, 37, pp.114~119 (2002)
- Schwindt W, "Magnetic resonance imaging protocols for examination of the neurocranium at 3 T", Eur Radiol, 13, pp.2170~2179 (2003)
- Krautmacher C, "Brain tumors: full- and half-dose contrast-enhanced MR imaging at 3.0 T compared with 1.5 T--Initial Experience", Radiology, 237, pp.1014~1019 (2005)
- Pfeuffer J, "Zoomed functional imaging in the human brain at 7 Tesla with simultaneous high spatial and high temporal resolution", Neuroimage, 17, pp.272~286 (2002)
- Vaughan JT, "7T vs. 4T: RF power, homogeneity, and signal-to-noise comparison in head images", Magn Reson Med, 46, pp.24~30 (2001)
- Ugurbil K, "Ultrahigh field magnetic resonance imaging and spectroscopy", Magn Reson Imaging, 21, pp.1263~1281 (2003)
- Gizewski ER, "fMRI at 7 T: whole-brain coverage and signal advantages even infratentorially", Neuroimage, 37, pp.761~768 (2007)
- Biswas J, "Brain tumor enhancement in magnetic resonance imaging: comparison of signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) at 1.5 versus 3 tesla", Invest Radiol, 40, pp.792~797 (2005)
- Lupo JM, "GRAPPA-based susceptibility-weighted imaging of normal volunteers and patients with brain tumor at 7 T", Magn Reson Imaging, 27, pp.480~488 (2009)
- Monninghoff C, "Theysohn JM, et al. Imaging of brain metastases of bronchial carcinomas with 7 T MRI - initial results", Rofo, 182, pp.764~772 (2010)
- Yuh WT, "Simonson TM, Mayr NA, Fisher DJ. The effect of contrast dose, imaging time, and lesion size in the MR detection of intracerebral metastasis", AJNR Am J Neuroradiol, 16, pp.373~380 (1995)
- Akeson P, "Brain metastases--comparison of gadodiamide injectionenhanced MR imaging at standard and high dose, contrastenhanced CT and non-contrast-enhanced MR imaging", Acta Radiol, 36, pp.300~306 (1995)
- Broome DR, "Gadodiamide-associated nephrogenic systemic fibrosis: why radiologists should be concerned", AJR Am J Roentgenol, 188, pp.586~592 (2007)
- Sadowski EA, "Nephrogenic systemic fibrosis: risk factors and incidence estimation", Radiology, 243, pp.148~157 (2007)
- Thomsen HS, "Nephrogenic systemic fibrosis: A serious late adverse reaction to gadodiamide", Eur Radiol, 16, pp.2619~2621 (2006)