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조기난소부전의 한약 치료에 대한 무작위 대조군 임상 연구 고찰

Review of Randomized controlled Trials on Korean Herbal Medicine Treatment for Premature Ovarian Insufficiency

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초록

Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of korean herbal medicine on premature ovarian insufficiency. Methods: Researchers searched for randomized controlled trial of based on korean herbal medicine and premature ovarian insufficiency. The paper search was conducted through 7 online databases on April 20, 2024. Results: 12 studies were included after selection and exclusion criteria. 4 studies compared herbal medicine with hormone replacement therapy or placebo. 8 studies compared combined treatment of herbal medicine and hormone replacement therapy, with hormone replacement therapy alone. All studies reported significant improvement on hormone, antral follicle count (AFC), total effective rate and associated symptoms. There were no serious adverse effects. Conclusions: This study suggests that herbal medicine has benefit for treating symptoms and ovarian function of premature ovarian insufficiency. For reliable evidence, further research on pregnancy or long-term follow-up is needed.

Abstract

Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of korean herbal medicine on premature ovarian insufficiency. Methods: Researchers searched for randomized controlled trial of based on korean herbal medicine and premature ovarian insufficiency. The paper search was conducted through 7 online databases on April 20, 2024. Results: 12 studies were included after selection and exclusion criteria. 4 studies compared herbal medicine with hormone replacement therapy or placebo. 8 studies compared combined treatment of herbal medicine and hormone replacement therapy, with hormone replacement therapy alone. All studies reported significant improvement on hormone, antral follicle count (AFC), total effective rate and associated symptoms. There were no serious adverse effects. Conclusions: This study suggests that herbal medicine has benefit for treating symptoms and ovarian function of premature ovarian insufficiency. For reliable evidence, further research on pregnancy or long-term follow-up is needed.

참고문헌 (35)

  1. Minkin MJ, "Menopause : Hormones, Lifestyle, and Optimizing Aging", Obstet Gynecol Clin North Am, 46(3), pp.501~514 (2019)
  2. European Society for Human Reproduction and Embryology (ESHRE) Guideline Group on POI, "ESHRE Guideline: management of women with premature ovarian insufficiency", Hum Reprod, 31(5), pp.926~937 (2016)
  3. Machura P, "Premature ovarian insufficiency-hormone replacement therapy and management of long-term consequences", Prz Menopauzalny, 17(3), pp.135~138 (2018)
  4. Webber L, "HRT for women with premature ovarian insufficiency : a comprehensive review", Hum Reprod Open, 2017(2), pp.hox007~ (2017)
  5. Hipp HS, "Reproductive and gynecologic care of women with fragile X primary ovarian insufficiency(FXPOI)", Menopause, 23(9), pp.993~999 (2016)
  6. Korean Oriental Society of Obstetrics and Gynecology, "Oriental Obstetrics and Gynecology vol. 2", pp.19~21 (2021), Euiseongdang
  7. Bu S., "Bucheongjunamyeogwa", pp.95~96 (1969), Munhwadoseogongsa
  8. Jiang W, "Clinical Efficacy of Bushen Huoxue Tang on the Treatment of Premature Ovarian Insufficiency and Its Influence on Immune Factors", World Journal of Integrated Traditional and Western Medicine, 19(03), pp.596~600 (2024)
  9. Xia YQ, "Effects of Zhu’s Tiaojing Recipe on Premature Ovarian Insufficiency and Immune Damage Induced by Inflammation", World Chinese Medicine, 8(15), pp.2190~2194 (2023)
  10. Chen WY, "Effects of Jiawei Zuogui Pill Combined with Estrogen and Progesterone Sequential Treatment on the Hemodynamics, Oxidative Stress and Immune Factors of Uterine Artery in Patients with Premature Ovarian Insufficiency", Progress in Modern Biomedicine, 23(16), pp.3097~3101 (2023)
  11. Zhou JY, "Clinical observation on tonifying kidney and soothing liver method in treatment of POI of Liver stagnation and Kidney deficiency syndrome", Information on TCM, 39(12), pp.56~61 (2022)
  12. He CH, "Effect of Bushen Shugan Formula on success rate of pregnancy in patients with POI accompanied with infertility", Information on TCM, 39(6), pp.72~75 (2022)
  13. Zhang H, "Effects of Yishen Yangluan Recipe on Ovarian Reserve Function, Expression of Bcl-2", Bax in Egg Granulosa Cells and PI3K, Guiding Journal of Traditional Chinese Medicine and Pharmacology, pp.2021, 27(09)[DOI]
  14. Yuan F, "Treatment of Premature Ovarian Insufficiency with Kidney Deficiency and Liver Depression with Integrative Medicine", Acta Chinese Medicine, 36(10), pp.2233~2238 (2021)
  15. Cheng L, "yu yin tang lian he ci er chun di qu yun tong pian zhi liao zao fa xing luan chao gong neng bu quan(育阴汤联合雌二醇地屈孕酮片治疗早发性卵巢功能不全)", Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 31(02), pp.24~25 (2021)
  16. Wu Q, "Clinical Observation of Bushenhuoxue Decoction in Treatment of Premature Ovarian Insufficiency of Kidney Deficiency Type", Hubei Journal of TCM, 43(01), pp.24~27 (2021)
  17. Sui J, "Ameliorative effect of Zhu’s Tiaojing Recipe on ovarian blood supply in POI patients with type of idney deficiency and blood stasis", Shanghai Journal of Traditional Chinese Medicine, 55(11), pp.50~53 (2021)
  18. Lu C, "Clinical observation on 30 cases of premature ovarian insufficiency with liver depression and kidney deficiency type treated by Yijing Tang", J Gansu University of Chinese Medicine, 37(02), pp.61~66 (2020)
  19. Cao XJ, "A randomized, doubleblind, placebo-controlled trial of Chinese herbal medicine capsules for the treatment of premature ovarian insufficiency", Menopause, 25(8), pp.918~926 (2018)
  20. So ES, "Trends of Premature and Early Menopause and Their Risk Factors among Korean Women", J Korea Academia-Industrial Cooperation Soc, 25(2), pp.122~129 (2024)
  21. Kim MK, "A Review of the Domestic Study Trends on Premature Ovarian Failure Treated with Korean Medicine", J Korean Obestet Gynecol, 33(3), pp.20~39 (2020)
  22. Heo J, "Donguibogam", pp.1745~ (2005), Donguibogam publisher
  23. Beral V, "Evidence from randomised trials on the long-term effects of hormone replacement therapy", The Lancet, 360(9337), pp.942~944 (2002)
  24. Yang L, "The role of oxidative stress and natural antioxidants in ovarian aging", Front Pharmacol, 11, pp.617843~ (2021)
  25. Donnapee S, "Cuscuta chinensis Lam. : A systematic review on ethnopharmacology, phytochemistry and pharmacology of an important traditional herbal medicine", J Ethnopharmacol, 157, pp.292~308 (2014)
  26. Huang C, "Quercetin and flavonoids from Cuscuta chinensis Lam. inhibit tripterygium glycoside-induced premature ovarian failure progression via PI3KAKT signaling pathway", Phcog Mag, 17(75), pp.475~481 (2021)
  27. Pellizzari P, "Colour Doppler analysis of ovarian and uterine arteries in women with hypoestrogenic amenorrhoea", Hum Reprod, 17(12), pp.3208~3212 (2002)
  28. Yu L, "Diagnosis of Idiopathic Premature Ovarian Failure by Color Doppler Ultrasound under the Intelligent Segmentation Algorithm", Comput Math Methods Med, 2022, pp.2645607~ (2022)
  29. Bidet M, "Resumption of Ovarian Function and Pregnancies in 358Patients with Premature Ovarian Failure", J Clin Endocrinol Metab, 96(12), pp.3864~3872 (2011)
  30. Lee JR, "Anti-Mullerian hormone and female reproduction", Obstet Gynecol Sci, 52(3), pp.285~300 (2009)
  31. Kuang X, "The Evaluation of Ovarian Function Recovery Following Treatment of Primary Ovarian Insufficiency : A Systematic Review", Front Endocrinol, 13, pp.855992~ (2022)
  32. Practice Committee of the American Society for Reproductive Medicine., "Testing and interpreting measures of ovarian reserve: a committee opinion", Fertil Steril, 114(6), pp.1151~1157 (2020)
  33. Kunicki M, "Immunophenotypic profiles and inflammatory markers in Premature Ovarian Insufficiency", J Reprod Immunol, 164, pp.104253~ (2024)
  34. Kim JH, "Tumor necrosis factor-alpha promoter polymorphisms are associated with idiopathic primary ovarian insufficiency in Korean women", Fertil Steril, 98(5), pp.1260~1265 (2012)
  35. Bai X, "Signaling pathway intervention in premature ovarian failure", Frontiers in Medicine, 9, pp.999440~ (2022)

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