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Dilated Cardiomyopathy in Acromegaly: a Case Report with Cardiac MR Findings

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초록

Acromegaly is a rare endocrine disorder caused by excessive secretion of the growth hormone. There is a wide range of clinical manifestations from somatic symptoms to respiratory or cardiac failure. Among them, cardiovascular involvement is a leading cause of morbidity and mortality. There are relatively few cases reporting cardiac magnetic resonance imaging (CMR) findings of cardiomyopathy in patients with acromegaly. Thus, we report a case of acromegaly showing dilated cardiomyopathy focusing on the findings of CMR.

Abstract

Acromegaly is a rare endocrine disorder caused by excessive secretion of the growth hormone. There is a wide range of clinical manifestations from somatic symptoms to respiratory or cardiac failure. Among them, cardiovascular involvement is a leading cause of morbidity and mortality. There are relatively few cases reporting cardiac magnetic resonance imaging (CMR) findings of cardiomyopathy in patients with acromegaly. Thus, we report a case of acromegaly showing dilated cardiomyopathy focusing on the findings of CMR.

참고문헌 (9)

  1. Lavrentaki A, "Epidemiology of acromegaly: review of population studies", Pituitary, 20, pp.4~9 (2017)
  2. Lugo G, "Clinical manifestations and diagnosis of acromegaly", Int J Endocrinol, 2012, pp.540398~ (2012)
  3. Bihan H, "Long-term outcome of patients with acromegaly and congestive heart failure", J Clin Endocrinol Metab, 89, pp.5308~5313 (2004)
  4. dos Santos Silva CM, "Low frequency of cardiomyopathy using cardiac magnetic resonance imaging in an acromegaly contemporary cohort", J Clin Endocrinol Metab, 100, pp.4447~4455 (2015)
  5. Sharma AN, "Acromegalic cardiomyopathy: epidemiology, diagnosis, and management", Clin Cardiol, 41, pp.419~425 (2018)
  6. Dabir D, "Reference values for healthy human myocardium using a T1 mapping methodology:results from the International T1 multicenter cardiovascular magnetic resonance study", J Cardiovasc Magn Reson, 16, pp.69~ (2014)
  7. Haaf P, "Cardiac T1 mapping and extracellular volume (ECV) in clinical practice: a comprehensive review", J Cardiovasc Magn Reson, 18, pp.89~ (2016)
  8. Dargad RR, "Acromegaly with dilated cardiomyopathy", J Assoc Physicians India, 64, pp.96~97 (2016)
  9. Giesbrandt KJ, "Diffuse diseases of the myocardium: MRI-pathologic review of nondilated cardiomyopathies", AJR Am J Roentgenol, 200, pp.W266~W273 (2013)

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