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Lipoma-like Liposarcoma with Osteosarcomatous Dedifferentiation of the Chest Wall : A Case Report

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초록

We report a case of liposarcoma with osteosarcomatous dedifferentiation of the chest wall in a 58-year-old man, which had been initially mistaken as myositis ossificans. CT and MRI demonstrated a soft tissue mass consisting of two components: a non-lipomatous area with amorphous calcification/ossification and a well-encapsulated fatty component. Based on local excision in the non-lipomatous area, myositis ossificans was initially diagnosed. As the mass was gradually enlarging, however, wide excision including the fatty component was performed and histological assessment revealed lipoma-like, well-differentiated liposarcoma with high-grade osteosarcomatous dedifferentiation. Here, we describe the radiological-pathological features of this rare neoplasm.

Abstract

We report a case of liposarcoma with osteosarcomatous dedifferentiation of the chest wall in a 58-year-old man, which had been initially mistaken as myositis ossificans. CT and MRI demonstrated a soft tissue mass consisting of two components: a non-lipomatous area with amorphous calcification/ossification and a well-encapsulated fatty component. Based on local excision in the non-lipomatous area, myositis ossificans was initially diagnosed. As the mass was gradually enlarging, however, wide excision including the fatty component was performed and histological assessment revealed lipoma-like, well-differentiated liposarcoma with high-grade osteosarcomatous dedifferentiation. Here, we describe the radiological-pathological features of this rare neoplasm.

참고문헌 (10)

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  7. Yu L, "Dedifferentiated liposarcoma of soft tissue with high-grade osteosarcomatous dedifferentiation", Radiographics, 25, pp.1082~1086 (2005)
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  9. Yoshida A, "Well-differentiated liposarcoma with low-grade osteosarcomatous component", Am J Surg Pathol, 34(9), pp.1361~1366 (2010)
  10. Evans HL, "Liposarcoma: a study of 55 cases with reassessment of its classification", Am J Surg Pathol, 3, pp.507~523 (1979)

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