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Coexistence of Intracranial Squamous Cell Carcinoma and Epidermoid Cyst: a Case with Consecutive Imaging Findings

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초록

In contrast to well-known imaging findings of intracranial epidermoid cysts on magnetic resonance imaging, those of intracranial squamous cell carcinoma (SqCC) are relatively unknown. We present a case of coexistence of intracranial SqCC and epidermoid cyst, with consecutive follow up over 14 months. Based on our case, a solid enhancing portion adjacent to a typically-looking epidermoid cyst may become a clue for coexistence of intracranial SqCC. An initial contrast enhancement and/or heterogeneous signal on diffusion weighted imaging may become a useful diagnostic clue, but more importantly, sudden rapid growth is important in formulating diagnosis.

Abstract

In contrast to well-known imaging findings of intracranial epidermoid cysts on magnetic resonance imaging, those of intracranial squamous cell carcinoma (SqCC) are relatively unknown. We present a case of coexistence of intracranial SqCC and epidermoid cyst, with consecutive follow up over 14 months. Based on our case, a solid enhancing portion adjacent to a typically-looking epidermoid cyst may become a clue for coexistence of intracranial SqCC. An initial contrast enhancement and/or heterogeneous signal on diffusion weighted imaging may become a useful diagnostic clue, but more importantly, sudden rapid growth is important in formulating diagnosis.

참고문헌 (10)

  1. Ahmed I, "Neurosurgical management of intracranial epidermoid tumors in children. Clinical article", J Neurosurg Pediatr, 4, pp.91~96 (2009)[DOI]
  2. Roh TH, "Intracranial squamous cell carcinoma arising in a cerebellopontine angle epidermoid cyst: a case report and literature review", Medicine (Baltimore), 96, pp.e9423~ (2017)[DOI]
  3. Wagle WA, "Magnetic resonance imaging of fourth ventricular epidermoid tumors", Arch Neurol, 48, pp.438~440 (1991)[DOI]
  4. Min-Su Kim, "Primary Intracranial Squamous Cell Carcinoma in the Brain Stem with a Cerebellopontine Angle Epidermoid Cyst", 대한신경외과학회지, 44(6), pp.401~404 (2008), 대한신경외과학회
  5. Hamlat A, "Malignant transformation of intra-cranial epithelial cysts: systematic article review", J Neurooncol, 74, pp.187~194 (2005)[DOI]
  6. Uchino A, "Intracranial epidermoid carcinoma: CT and MRI", Neuroradiology, 37, pp.155~158 (1995)[DOI]
  7. Abramson RC, "Multiple complications from an intracranial epidermoid cyst: case report and literature review", Neurosurgery, 24, pp.574~578 (1989)[DOI]
  8. Nakao Y, "Malignant transformation 20 years after partial removal of intracranial epidermoid cyst--case report", Neurol Med Chir (Tokyo), 50, pp.236~239 (2010)[DOI]
  9. Ozutemiz C, "Imaging findings of an epidermoid cyst with malignant transformation to squamous cell carcinoma", Turk Neurosurg, 27, pp.312~315 (2017)
  10. Nawashiro H, "Diffusion-weighted MRI of an intracranial epidermoid with malignant transformation", Neuroradiology, 43, pp.891~ (2001)[DOI]

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