중증급성호흡기증후군(SARS) 치료에 사용된 한약 처방에 대한 고찰 - WHO 보고서(2004)에 사용된 처방을 중심으로
An Overview of the Herbal Remedies for Severe Acute Respiratory Syndrome (SARS) in WHO Official Report (2004)
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Background: Early in November 2002, severe acute respiratory syndrome (SARS) began to spread throughout thirty-two countries around the world. A total of 5,327 cases were reported in China, including 1,755 cases in Hong Kong and 655 in Taiwan. The total number of cases reported from Canada and Singapore was more than 200. The total number of SARS cases world-wide reached 8,437 with incidences. Mortality from SARS is estimated at around 11%. Under the guidance of the World Health Organization (WHO), clinical studies on the use of integrated herbal medicine and western medicine for treating SARS were carried out in China and Hong Kong. The official report suggested that integrated treatment was more effective than western medicine alone in clinical symptoms, lung inflammation, blood oxygen saturation, immunological functions and others. Objective : To overview the treatment principle and the prescriptions according to the regimens and the stages for SARS of the reports, and further to broaden our knowledge of treatment of acute infectious diseases using natural herbal medicine. Methods : We reviewed nine of WHO SARS reports that comprehensively described the principles and methods of treatment and summarized them into eight treatment methods. We analyzed the herbal formulae on the basis of their treatment principles, evaluated them in accordance with warm disease study, listed frequently used herbs, and assessed patent prescriptions and herbal injections that were mentioned in the reports. Results and Conclusion : The reports divided the course of SARS into 3 to 6 stages such as high fever stage, fastigium stage, and convalescent stage. Frequently used herbs were Radix Scutellariae, Radix Paeoniae, Radix Astragali, Semen Armeniacae, Radix Pseudostellariae, Radix Ophiopogonis, and Fructus Schizandrae. Herbal decoctions were the primary method of treatment, while extracts or injections were secondary. Prescriptions were mainly based on the warm disease study. SARS is a viral disease caused by corona virus, and herbal medicine is proven to be effective against it. We believe that evidences and experiences from SARS cases can be a good reference to further researches on acute infectious diseases.
Abstract
Background: Early in November 2002, severe acute respiratory syndrome (SARS) began to spread throughout thirty-two countries around the world. A total of 5,327 cases were reported in China, including 1,755 cases in Hong Kong and 655 in Taiwan. The total number of cases reported from Canada and Singapore was more than 200. The total number of SARS cases world-wide reached 8,437 with incidences. Mortality from SARS is estimated at around 11%. Under the guidance of the World Health Organization (WHO), clinical studies on the use of integrated herbal medicine and western medicine for treating SARS were carried out in China and Hong Kong. The official report suggested that integrated treatment was more effective than western medicine alone in clinical symptoms, lung inflammation, blood oxygen saturation, immunological functions and others. Objective : To overview the treatment principle and the prescriptions according to the regimens and the stages for SARS of the reports, and further to broaden our knowledge of treatment of acute infectious diseases using natural herbal medicine. Methods : We reviewed nine of WHO SARS reports that comprehensively described the principles and methods of treatment and summarized them into eight treatment methods. We analyzed the herbal formulae on the basis of their treatment principles, evaluated them in accordance with warm disease study, listed frequently used herbs, and assessed patent prescriptions and herbal injections that were mentioned in the reports. Results and Conclusion : The reports divided the course of SARS into 3 to 6 stages such as high fever stage, fastigium stage, and convalescent stage. Frequently used herbs were Radix Scutellariae, Radix Paeoniae, Radix Astragali, Semen Armeniacae, Radix Pseudostellariae, Radix Ophiopogonis, and Fructus Schizandrae. Herbal decoctions were the primary method of treatment, while extracts or injections were secondary. Prescriptions were mainly based on the warm disease study. SARS is a viral disease caused by corona virus, and herbal medicine is proven to be effective against it. We believe that evidences and experiences from SARS cases can be a good reference to further researches on acute infectious diseases.
참고문헌 (28)
- "Preparing for the second wave: lessons from current outbreaks"[URL]
- "Centers for Disease Control and Prevention"[URL]
- "한국 질병관리본부 홈페이지"[URL]
- Underwood A, "Scary lessons of 1918 (A new book details a deadly flu. Will it happen again?)", Newsweek, 16(7), pp.41~ (2004)
- 장인수, "중증급성호흡기증후군(SARS)의 한약 치료에 관련된 WHO 임상논문 보고에 대한 개관", 대한한방내과학회지, 26(2), pp.440~452 (2005), 대한한방내과학회
- Clinical Research Task Force for Treatment of SARS with Integrated TCM, "Clinical research on treatment of SARS with integrated Traditional Chinese medicine and Western Medicine (Report 1)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.11~29 (2004)
- Liu B, "Clinical efficacy of the treatment of SARS with integrated Traditional Chinese medicine and Western medicine: an analysis of 524 cases (Report 2)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.31~52 (2004)
- Lin L, "Clinical study on 103 inpatients undergoing therapy with integrated Traditional Chinese medicine and Western medicine (Report 4)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.65~82 (2004)
- Tong X, "Clinical observations of 11 patients with SARS treated with Traditional Chinese medicine (Report 5)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.83~98 (2004)
- Li J, "Effects of applying integrated therapy with Traditional Chinese medicine and Western medicine on liver and kidney functions in patients with SARS (Report 6)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.98~110 (2004)
- Zhang Y, "Clinical research on 63 patients with SARS treated with integrated Traditional Chinese medicine and Western medicine (Report 7)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.111~119 (2004)
- Li J, "Influence of integrated therapy with Traditional Chinese medicine and Western medicine on lymphocytes and T-lymphocyte subpopulations of patients with SARS (Report 8)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.121~130 (2004)
- Wang R, "Analysis of the clinical curative effects on patients with SARS of treatment with Traditional Chinese medicine and Western medicine (Report 9)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.131~141 (2004)
- Jiang Z, "Evaluation of clinical curative effects of Traditional Chinese medicine in treatment of patients convalescing from SARS (Report 10)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.143~155 (2004)
- Leung P, "A herbal formula for the prevention of transmission of SARS during the SARS epidemic in Hong Kong Special Administrative Region - a prospective cohort study (Report A)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.157~169 (2004)
- "Severe acute respiratory syndrome"[URL]
- Zhang B, "Manifestation of symptoms in patients with SARS and analysis of the curative effect of treatment with integrated Traditional Chinese medicine and Western medicine.(Reprot 3)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.53~64 (2004)
- Hui P, "Effects of Chinese medicine on patients convalescing from SARS in Hong Kong special administrative region-a prospective non- randomized controlled trial (Report B", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.171~182 (2004)
- Hui P, "Traditional Chinese medicine in the management of patients with SARS in Hong Kong Special Administrative Region - a case-control study of 24 patients(Report C)", SARS: Clinical trials on treatment using a combination of Traditional Chinese medicine and Western medicine, pp.183~196 (2004)
- Liu J, "Chinese herbal medicine for severe acute respiratory syndrome: a systematic review and meta-analysis", J Altern Complement Med, 10(6), pp.1041~1051 (2004)
- Lau J, "The use of an herbal formula by hospital care workers during the severe acute respiratory syndrome epidemic in Hong Kong to prevent severe acute respiratory syndrome transmission, relieve influenza-related symptoms, and improve quality of life: a prospective cohort study", J Altern Complement Med, 11(1), pp.49~55 (2005)
- Lin L, "A retrospective study on clinical features of and treatment methods for 77 severe cases of SARS", Am J Chin Med, 31(6), pp.821~839 (2003)
- Chen Z, "Statistical evidence for the usefulness of Chinese medicine in the treatment of SARS", Phytother Res, 18(7), pp.592~594 (2004)
- 吳國通著, "國譯溫病條辨", pp.94~ (2005), 집문당
- 이용범, "國譯 溫病縱橫", pp.62~ (2006), 集文堂
- 李劉坤, "임상온병학특강", pp.240~ (2001), 대성의학사
- Jia W, "Is traditional Chinese medicine useful in the treatment of SARS?", Phytother Res, 17(7), pp.840~841 (2003)
- Hsu C-H, "An Evaluation of the Additive Effect of Natural Herbal Medicine on SARS or SARS-like Infectious Diseases in 2003: A Randomized, Double-blind, and Controlled Pilot Study", Evid Based Complement Alternat Med, 5, pp.355~362 (2008)
