일개 한의의료기관에서 COVID 19 증상 완화를 위해 한약이 투여된 환자 63례에 대한 보고 : 후향적 차트 리뷰 연구
Reports of 63 Patients Treated with Herbal Medicine to Relieve Symptoms of COVID-19 at One Korean Medicine Clinic: A Retrospective Chart Review
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Objectives: The purpose of this study was to report on the cases and prescriptions of non-face-to-face care performed to alleviate COVID-19 symptoms and to present their results. Methods: This study was conducted on 63 COVID-19 patients who visited the Ilsan Hamsoa Korean Medicine Clinic from January 24 to June 11, 2022. We retrospectively analyzed all 63 patient charts and amassed COVID-19-related symptoms and their changes according to clinical characteristics and outcomes. Results: All 63 COVID-19 patients complained of symptoms, such as coughing, sore throat, sputum, fever, headache, myalgia, rhinorrhea, nasal obstruction, postnasal drip, and voice change. In total, 30 patients were administered Eunma-san, 6 patients were administered Eungyo-san plus Mahaenggamseok-tang, 10 patients were administered Galgeunhaegi-tang, 7 patients were administered Eungyo-san, 6 patients were administered Maekmundong-tang, and 4 patients were administered Jugyeopseoggo-tang. Improvements in symptoms due to herbal medicine included the disappearance of COVID-19 fever (22 cases) within 3.59±4.22 days, sore throat (32 cases) within 4.37±2.98 days, and cough (36 cases) within 4.86±3.11 days. Conclusion: Various herbal medicine prescriptions were effective COVID-19 treatments, indicating that herbal medicines may be alternative treatment options for COVID-19. However, the evidence should be supplemented with better designed prospective research on individual prescriptions.
Abstract
Objectives: The purpose of this study was to report on the cases and prescriptions of non-face-to-face care performed to alleviate COVID-19 symptoms and to present their results. Methods: This study was conducted on 63 COVID-19 patients who visited the Ilsan Hamsoa Korean Medicine Clinic from January 24 to June 11, 2022. We retrospectively analyzed all 63 patient charts and amassed COVID-19-related symptoms and their changes according to clinical characteristics and outcomes. Results: All 63 COVID-19 patients complained of symptoms, such as coughing, sore throat, sputum, fever, headache, myalgia, rhinorrhea, nasal obstruction, postnasal drip, and voice change. In total, 30 patients were administered Eunma-san, 6 patients were administered Eungyo-san plus Mahaenggamseok-tang, 10 patients were administered Galgeunhaegi-tang, 7 patients were administered Eungyo-san, 6 patients were administered Maekmundong-tang, and 4 patients were administered Jugyeopseoggo-tang. Improvements in symptoms due to herbal medicine included the disappearance of COVID-19 fever (22 cases) within 3.59±4.22 days, sore throat (32 cases) within 4.37±2.98 days, and cough (36 cases) within 4.86±3.11 days. Conclusion: Various herbal medicine prescriptions were effective COVID-19 treatments, indicating that herbal medicines may be alternative treatment options for COVID-19. However, the evidence should be supplemented with better designed prospective research on individual prescriptions.
참고문헌 (34)
- "Coronavirus Pandemic (COVID-19). Our World in Data" (2020)[URL]
- Lazarus JV, "A global survey of potential acceptance of a COVID-19 vaccine", Nat Med, 27(2), pp.225~228 (2021)[DOI]
- Polack FP, "Safety and Efficacy of the BNT162b2 mRNA Covid-19Vaccine", N Engl J Med, 383(27), pp.2603~2615 (2020)[DOI]
- Kaur RJ, "Adverse Events Reported From COVID-19 Vaccine Trials: A Systematic Review", Indian J Clin Biochem (2021)[DOI]
- Jorgensen SCJ, "Remdesivir : Review of Pharmacology, Pre-clinical Data, and Emerging Clinical Experience for COVID-19", Pharmacother J Hum Pharmacol Drug Ther, 40(7), pp.659~671 (2020)[DOI]
- Ang L, "Herbal Medicine Intervention for the Treatment of COVID-19 : A Living Systematic Review and Cumulative Meta-Analysis", Front Pharmacol, 13, pp.906764~ (2022)[DOI]
- Takayama S, "Prevention and Recovery of COVID-19 Patients With Kampo Medicine : Review of Case Reports and Ongoing Clinical Trials", Front Pharmacol, 12, pp.1484~ (2021)[DOI]
- Jeon Sae-Rom, "Complementary and alternative medicine (CAM) interventions for COVID-19: An overview of systematic reviews", Integrative Medicine Research, 11(3), pp.1~9 (2022), 한국한의학연구원[DOI]
- 권승원, "Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review", Integrative Medicine Research, 9(3), pp.1~7 (2020), 한국한의학연구원[DOI]
- 김동수, "Telemedicine Center of Korean Medicine for treating patients with COVID-19: a retrospective analysis", Integrative Medicine Research, 9(3), pp.1~5 (2020), 한국한의학연구원[DOI]
- 김광호, "청폐배독탕 및 청폐배독탕거마황을 사용해 COVID-19 증상의 개선을 보인 증례 보고 : 후향적 사례군 연구", 대한한방내과학회지, 43(2), pp.264~273 (2022), 대한한방내과학회[DOI]
- 강성우, "아스트라제네카 코로나19 백신(ChAdOx1 nCoV-19", AZD1222)을 접종한 환자에서 한방 치료의 안전성 : 사례군 연구, 2021, pp.42(4), 590~604[DOI]
- 김지희, "Covid-19 백신 접종 후 발생한 길랑-바레 증후군에 동반된 양측성 안면마비 1례", 한방안이비인후피부과학회지, 35(1), pp.81~90 (2022), 대한한방안이비인후피부과학회
- 이슬, "코로나19 후유증을 호소하는 태음인 환자에 대한 치험 1례", 사상체질의학회지, 33(4), pp.32~42 (2021), 사상체질의학회[DOI]
- 송지훈, "코로나바이러스감염증-19 (COVID-19) 백신 접종 후 재발한 대상포진 치험 1례", 한방안이비인후피부과학회지, 34(4), pp.181~197 (2021), 대한한방안이비인후피부과학회
- Kang B, "Prevention and management of adverse events following COVID-19 vaccination using traditional Korean medicine : An online survey of public health doctors", World J Clin Cases, 10(28), pp.10053~10065 (2022)[DOI]
- Micallef MJ, "The natural plant product tryptanthrin ameliorates dextran sodium sulfate-induced colitis in mice", Int Immunopharmacol, 2(4), pp.565~578 (2002)
- Lin H, "Exploring the treatment of COVID-19 with Yinqiao powder based on network pharmacology", Phytother Res, 35(5), pp.2651~2664 (2021)[DOI]
- Fan Y, "Efficacy and safety of yinqiao powder combined with western medicine in the treatment of pneumonia : A systematic review and metaanalysis", Complement Ther Clin Pract, 42, pp.101297~ (2021)[DOI]
- Hong ND, "Studies on the Efficacy of Combined Preparation of Crude Drugs(XVII)-Effects of ‘Bojungikgi-Tang’on the Digestive System, Blood Pressure and Diuretic Actions", Natural Product Sciences, 17(3), pp.223~231 (1986)
- Lee JG, "Effect of Mahaenggamseok-tang-gagambang on CD3, CD4, CD8 Cells in OVA-induced Asthmatic Mice", Daejeon University Institute of Oriental Medicine, 17(1), pp.67~74 (2008)
- Hsieh CF, "Mechanism by which ma-xingshi-gan-tang inhibits the entry of influenza virus", J Ethnopharmacol, 143(1), pp.57~67 (2012)[DOI]
- Lin SK, "Traditional Chinese medicine therapy decreases the pneumonia risk in patients with dementia", Medicine(Baltimore), 95(37), pp.e4917~ (2016)[DOI]
- Wang C, "Oseltamivir Compared With the Chinese Traditional Therapy Maxingshigan-Yinqiaosan in the Treatment of H1N1 Influenza", Ann Intern Med, 155(4), pp.217~225 (2011)[DOI]
- Jeong SH, "A study on the anti-inflammatory action of Gagamgalgeunhaegi-tang", master, pp.2004
- Woo JS, "Effects of Galgun Hegi Tang on Immune Response in Mouse", J Korean Med, 11(2), pp.436~457 (1990)
- 김형갑, "葛根解肌湯의 항 Allergy 및 항염증 효과", 동의생리병리학회지, 23(2), pp.381~388 (2009), 한의병리학회
- Li XM, "Traditional Chinese medicine for the therapy of allergic disorders", Curr Opin Otolaryngol Head Neck Surg, 14(3), pp.191~196 (2006)[DOI]
- Kamei J, "Antitussive principles of Glycyrrhizae radix, a main component of the Kampo preparations Bakumondo-to(Mai-men-dong-tang)", Eur J Pharmacol, 469(1-3), pp.159~163 (2003)
- 김호, "麥門冬湯의 면역조절 효과", 동의생리병리학회지, 17(4), pp.946~951 (2003), 한의병리학회
- 김형원, "Elastase 매개성 폐조직 손상에 대한 麥門冬湯의 보호효과", 대한한의학회지, 32(2), pp.63~78 (2011), 대한한의학회
- Jin ZY, "Efficacy evaluation of Yinqiaosan and Zhuyegyaotang in adjuvant treatment of patients with severe pneumonia with the same syndrome of Wei and Qi", The clinical Research, 4, pp.115~116 (2021)
- The association of Korean Medicine, "Coronavirus Infectious Disease-19 Korean Medicine Treatment Recommendation. Vol 1" (2020), The association of Korean Medicine
- "Herbal medicines for fatigue or brain fog in Coronavirus disease 2019 (COVID-19)survivors: a prospective pilot clinical study"[URL]