굴(Crassostrea gigas)·다시마(Saccharina japonica) 발효분말의 스트레스 완화 및 수면 유도 효과
Stress Relaxation and Sleep Induction Effect of Fermented Sea Tangle Saccharina japonica and Oyster Crassostrea gigas Powder
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초록
Sleep is an essential biological process of which the underlying regulatory mechanisms involve numerous anatomical structures and biochemical substances that can be compromised by stress and the immune system. Gamma aminobutyric acid (GABA)is the main inhibitory neurotransmitter of the central nervous system (CNS). It is well established that activation of GABAA receptors promotes sleep. L. brevis BJ20 fermentation of sea tangle and oysters resulted in stress reduction and sleep inducing effects. This is the first study to report that GABA has the ability to induce sleep related hormones in mice; therefore, it has potential use as a natural sleep aid. These results suggested that sea tangle and oysters fermented by L. brevis BJ20 can be used as potential agents for stress reduction and sleep promotion
Abstract
Sleep is an essential biological process of which the underlying regulatory mechanisms involve numerous anatomical structures and biochemical substances that can be compromised by stress and the immune system. Gamma aminobutyric acid (GABA)is the main inhibitory neurotransmitter of the central nervous system (CNS). It is well established that activation of GABAA receptors promotes sleep. L. brevis BJ20 fermentation of sea tangle and oysters resulted in stress reduction and sleep inducing effects. This is the first study to report that GABA has the ability to induce sleep related hormones in mice; therefore, it has potential use as a natural sleep aid. These results suggested that sea tangle and oysters fermented by L. brevis BJ20 can be used as potential agents for stress reduction and sleep promotion
참고문헌 (14)
- Arnaud C, "Study of a GABA C receptor antagonist on sleep-waking behavior in rats", Psychopharmacology, 154, pp.415~419 (2001)
- Bastien CH, "Precipitating factors of insomnia", Behav Sleep Med, 2, pp.50~62 (2004)
- Claude G, "GABA Mechanisms and sleep", Neuroscience, 111, pp.231~239 (2002)
- Concas A, "The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines", Naunyn Schmiedeberg's Arch Pharmacol, 350, pp.294~300 (1994)
- Declerck AC, "Effects of Zolpidem and funitrazepam on nocturnal sleep of women subjectively complaining of insomnia", Psychopharmacology, 106, pp.497~501 (1992)
- Finnimore AJ, "The effect of the GABA agonist, baclofen, on sleep and breathing", Eur Resp, 8, pp.230~234 (1995)
- Krueger JM, "Humoral regulation of physiological sleep: Cytokines and GHRH", J Sleep Res, 1, pp.53~59 (1999)
- Lee B-J, "Antioxidant activity and γ-aminobutyric acid (GABA) content in sea tangle fermented by Lactobacillus brevis BJ20 isolated from tranditional fermented foods", Food Chemistry, 122, pp.271~276 (2010)[DOI]
- Monk TH, "Regularity of daily life in relation to personality, age, gender, sleep quality and circadian rhythms", J Sleep Res, 3, pp.196~205 (1994)
- Ohayon MM, "Insomnia and global sleep dissatisfaction in Finland", J Sleep Res, 11, pp.339~346 (2002)
- Risa J, "Screening of plants used in southern Africa for epilepsy and convulsions in the GABAA-benzodiazepine receptor assay", Journal of Ethno pharmacology, 93, pp.177~182 (2004)
- Roehrs T, "Sleepiness and ethanol effects on simulated driving", Alcohol Clin Exp Res, 18, pp.154~158 (1994)
- Sherin JE, "Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat", Journal of Neuroscience, 18, pp.4705~4721 (1998)
- Yun JO, "Pharmacokinehcs of caffeine sensitive and non-senstive volunteers and in the obese rat and the lean rat", Korean Pharm Sci, 37, pp.341~348 (1993)