간질성 방광염 환자 25예에 대한 임상적 고찰

Abstract

Background : Interstitial cystitis is a disorder of the bladder characterized by urgency and frequency of urination, and pelvic pain. The cause of interstitial cystitis is not clear. Modern medical treatments include behavioral therapy, medication, intravesical infusion therapy, and surgical treatment, but the goal of treatment is based on symptom relief rather than a cure. According to a recent report, in an animal model, oriental medicine treatment, Yukmijihwang-tang improved the symptoms of interstitial cystitis. However, clinical studies and experimental research are lacking. Objectives : In this study, we investigated Chuknyojetong-tang, acupuncture, moxibustion and bee venom for effect on interstitial cystitis. Methods : We target 25 patients diagnosed with interstitial cystitis at the university hospital and treated them for more than one month. We used acupuncture, Chuknyojetong-tang, bee venom. The effects were evaluated using ICSI and ICPI at the beginning and end of treatment. Results : All the 25 patients were female, average age was 53.3±13.5 years, and the average months of disease-duration was 69.0±59.8. The duration of treatment was 8.0±5.4 months, and 60% of patients were improved. After treatment, we used correlation coefficient method, Multiple regression analysis. ICSI difference increased as treatment period increased. ICPI difference increased, as age decreased. Total difference also increased, as treatment period increased. These results imply that treatment effect was improved. Conclusions : These findings suggest that Oriental medicine therapy using Chuknyojetong-tang, acupuncture, moxibusion, and bee venom would be very effective on interstitial cystitis.