Evaluating the role of vaccine to combat peste des petits ruminants outbreaks in endemic disease situation
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Among the main intimidation to the sheep and goat population, PPR outbreaks are causing huge losses especiallyin endemic areas. During recent times, six outbreaks of PPR were confirmed at semi-organized goat farms/herdsin various regions of Punjab province and Islamabad capital territory (ICT), Pakistan. The disease started afterintroduction of new animals at these farms with no history of previous PPR vaccination. The clinical signs appearedaffecting respiratory and enteric systems and spread quickly. Disease caused mortality of 10-20% and morbidityof 20-40% within a time period of four weeks. Morbidity and mortality rates were 30.38% (86/283) and 15.55%(44/283), respectively. Three treatment regimes were executed to demonstrate the role of vaccination duringoutbreak at these farms. First was to use only the broad spectrum antibiotics (Penicillin & Streptomycin and/ orTrimethoprim and Sulfadiazine) at two farms (Texilla and Attock). Second treatment regime was to use the samebroad spectrum antibiotic along with extensive fluid therapy (Farms at ICT-1 and ICT-2). The third regime was touse of broad spectrum antibiotic plus fluid therapy along with vaccinating the herd against PPR during first weekof outbreak (ICT-3 and ICT-4). The third scheme of treatment gave the better results as there was no mortality inthird week post-outbreak. Therefore, it is suggested to give proper importance to PPR vaccination along withconventional symptomatic treatment when dealing the PPR outbreaks in endemic disease conditions.
Abstract
Among the main intimidation to the sheep and goat population, PPR outbreaks are causing huge losses especiallyin endemic areas. During recent times, six outbreaks of PPR were confirmed at semi-organized goat farms/herdsin various regions of Punjab province and Islamabad capital territory (ICT), Pakistan. The disease started afterintroduction of new animals at these farms with no history of previous PPR vaccination. The clinical signs appearedaffecting respiratory and enteric systems and spread quickly. Disease caused mortality of 10-20% and morbidityof 20-40% within a time period of four weeks. Morbidity and mortality rates were 30.38% (86/283) and 15.55%(44/283), respectively. Three treatment regimes were executed to demonstrate the role of vaccination duringoutbreak at these farms. First was to use only the broad spectrum antibiotics (Penicillin & Streptomycin and/ orTrimethoprim and Sulfadiazine) at two farms (Texilla and Attock). Second treatment regime was to use the samebroad spectrum antibiotic along with extensive fluid therapy (Farms at ICT-1 and ICT-2). The third regime was touse of broad spectrum antibiotic plus fluid therapy along with vaccinating the herd against PPR during first weekof outbreak (ICT-3 and ICT-4). The third scheme of treatment gave the better results as there was no mortality inthird week post-outbreak. Therefore, it is suggested to give proper importance to PPR vaccination along withconventional symptomatic treatment when dealing the PPR outbreaks in endemic disease conditions.
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