라카디브 해역 몰디브 자생 해조류 Padina boryana 추출물의 항산화 효능 평가
Evaluation of the Antioxidant Efficacy of Padina boryana Extract from Maldivian Seaweed from Laccadive Sea Area
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Global warming has affected the distribution of organisms for decades and has displayed rapid ascent recently. Research into the effects on tropical organisms are vital. Padina boryana is a resourceful marine microalgae in the Maldives Sea in the Laccadive region. A 70% ethanol extraction (PBE) of this seaweed was used to investigate its antioxidant potential. Both in vitro and in vivo models were implemented. PBE exhibited protective potential against H2O2 induced apoptosis. ROS levels were suppressed due to PBE. PBE expressed a cytoprotective nature. In vivo experiments involving the zebra fish model conformed its validity. The antioxidant efficacy of PBE was dose dependent. Study outcomes suggest PBE has potential as a novel and valuable marine resource to aid the functional food and cosmeceutical industries.
Abstract
Global warming has affected the distribution of organisms for decades and has displayed rapid ascent recently. Research into the effects on tropical organisms are vital. Padina boryana is a resourceful marine microalgae in the Maldives Sea in the Laccadive region. A 70% ethanol extraction (PBE) of this seaweed was used to investigate its antioxidant potential. Both in vitro and in vivo models were implemented. PBE exhibited protective potential against H2O2 induced apoptosis. ROS levels were suppressed due to PBE. PBE expressed a cytoprotective nature. In vivo experiments involving the zebra fish model conformed its validity. The antioxidant efficacy of PBE was dose dependent. Study outcomes suggest PBE has potential as a novel and valuable marine resource to aid the functional food and cosmeceutical industries.
참고문헌 (22)
- 최예지, "남아프리카공화국 갈조류 Ecklonia maxima 줄기의 항산화 활성 평가", 한국해양바이오학회지, 11(1), pp.29~35 (2019), (사)한국해양바이오학회[DOI]
- Jin Dai, "Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties", Molecules, 15(10), pp.7313~7352 (2010), MDPI AG[DOI]
- Jun Deng, "Hexabromocyclododecane-induced developmental toxicity and apoptosis in zebrafish embryos", Aquatic Toxicology, 93(1), pp.29~36 (2009), Elsevier BV[DOI]
- Soo-Jin Heo, "Antioxidant activity of enzymatic extracts from a brown seaweed Ecklonia cava by electron spin resonance spectrometry and comet assay", European Food Research and Technology, 221(1-2), pp.41~47 (2005), Springer Science and Business Media LLC[DOI]
- S HEO, "Antioxidant activities of enzymatic extracts from brown seaweeds", Bioresource Technology, 96(14), pp.1613~1623 (2005), Elsevier BV[DOI]
- Louis J. Ignarro, "Nitric Oxide as a Signaling Molecule in the Vascular System: An Overview", Journal of Cardiovascular Pharmacology, 34(6), pp.879~886 (1999), Ovid Technologies (Wolters Kluwer Health)[DOI]
- 장덕영, "UVB 로부터 ROS를 유도한 제브라피쉬에 스피룰리나 에탄올 추출물의 항산화 및 보호효과에 관한 연구", 한국응용과학기술학회지, 35(2), pp.423~432 (2018), 한국응용과학기술학회[DOI]
- Thilina U. Jayawardena, "Padina boryana, a brown alga from the Maldives: inhibition of α-MSH-stimulated melanogenesis via the activation of ERK in B16F10 cells", Fisheries and Aquatic Sciences, 23(1), pp.1~9 (2020), 한국수산과학회[DOI]
- 강정일, "부챗말 Glucopyranosyldiacylglycerol의 탈모방지 효능", 생약학회지, 51(1), pp.41~48 (2020), 한국생약학회
- Min-Cheol Kang, "Antioxidant properties of a sulfated polysaccharide isolated from an enzymatic digest of Sargassum thunbergii", International Journal of Biological Macromolecules, 132, pp.142~149 (2019), Elsevier BV[DOI]
- 김현수, "식용 해마(Hippocampus abdominalis) 유래 펩신 가수분해물의 In vitro와 In vivo에서의 항산화 효능", 한국수산과학회지, 49(4), pp.445~453 (2016), 한국수산과학회
- 김혜경, "아롱부챗말과 그의 활성성분인 fucosterol의 미백 효과", 생명과학회지, 30(7), pp.598~605 (2020), 한국생명과학회[DOI]
- Hyun-Soo Kim, "Antioxidant efficacy of (−)-loliolide isolated from Sargassum horneri against AAPH-induced oxidative damage in Vero cells and zebrafish models in vivo", Journal of Applied Phycology, 32(5), pp.3341~3348 (2020), Springer Science and Business Media LLC[DOI]
- 김태연, "가감당귀음자의 항산화 효과와 자외선으로 유도된 각질형성세포 손상에 대한 보호효과", 동의생리병리학회지, 29(6), pp.475~484 (2015), 한의병리학회[DOI]
- 김연숙, "포도근 추출물의 항산화 활성 및 산화스트레스에 대한 세포 보호 효과", 한국식품영양과학회지, 47(2), pp.136~142 (2018), 한국식품영양과학회
- Seok-Chun Ko, "Effect of angiotensin I-converting enzyme (ACE) inhibition and nitric oxide (NO) production of 6,6′-bieckol, a marine algal polyphenol and its anti-hypertensive effect in spontaneously hypertensive rats", Process Biochemistry, 58, pp.326~332 (2017), Elsevier BV[DOI]
- Yoshimitsu Ohinata, "Protection from noise-induced lipid peroxidation and hair cell loss in the cochlea", Brain Research, 966(2), pp.265~273 (2003), Elsevier BV[DOI]
- 박진모, "부챗말 추출액이 H2O2에 의한 혈관내피세포주인 ECV304세포의 산화적 스트레스에 미치는 영향", 동의생리병리학회지, 22(6), pp.1431~1438 (2008), 한의병리학회
- Huili Wang, "Toxicity evaluation of β-diketone antibiotics on the development of embryo-larval zebrafish (Danio rerio)", Environmental Toxicology, 29(10), pp.1134~1146 (2014), Wiley[DOI]
- Sibel Yalçın, "HPLC Detection and Antioxidant Capacity Determination of Brown, Red and Green Algal Pigments in Seaweed Extracts", Journal of Chromatographic Science, 59(4), pp.325~337 (2021), Oxford University Press (OUP)[DOI]
- 양승렬, "품종별, 생육단계별 시설재배 오이의 페놀화합물 함량과항균효과 및 Tyrosinase 억제활성", 한국자원식물학회지, 26(5), pp.645~651 (2013), 한국자원식물학회[DOI]
- 양혜원, "제브라피쉬(Danio rerio)를 이용한 비소 고함류 3종 해조류 추출물의 급성독성평가", 한국수산과학회지, 51(1), pp.31~41 (2018), 한국수산과학회[DOI]