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New Cyclic Peroxides from a Sponge, Plakortis sp.

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Abstract

Two new cyclic peroxides were isolated from an undescribed sponge of the genus Plakortis sp. collected at Discovery Bay, Jamaica. The molecular structures were elucidated by interpreting 1D and 2D NMR and HRMS data. The cyclic peroxides, Compound 1 and 2, exhibited significant antimicrobial activity against pathogenic bacteria and fungi with IC50 values of 0.9-5.0μg/mL and 0.7-8.0μg/mL, respectively.

참고문헌 (11)

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