Whole genome sequence analysis of Ligilactobacillus agilis C7 isolated from pig feces revealed three bacteriocin gene clusters
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We here report the whole genome sequence of Ligilactobacillus agilis C7 with anti-listerialactivity, which was isolated from pig feces. The genome size of L. agilis C7 (~ 3.0 Mb) is relativelylarger compared with other L. agilis strains. L. agilis C7 carries three bacteriocin geneclusters encoding garvicin Q, salivaricin A, and Blp family class II bacteriocin. Garvicin Q andsalivaricin A are reported to be active against Listeria monocytogenes and Micrococcus luteus,respectively, as well as against other Gram-positive bacteria. Meanwhile, the bacteriocinencoded in the blp cassette was shown to be active against pneumococci, mediating intraspeciescompetition. This report highlights the potential of L. agilis C7 for the production ofbacteriocins inhibiting pathogenic bacteria.
Abstract
We here report the whole genome sequence of Ligilactobacillus agilis C7 with anti-listerialactivity, which was isolated from pig feces. The genome size of L. agilis C7 (~ 3.0 Mb) is relativelylarger compared with other L. agilis strains. L. agilis C7 carries three bacteriocin geneclusters encoding garvicin Q, salivaricin A, and Blp family class II bacteriocin. Garvicin Q andsalivaricin A are reported to be active against Listeria monocytogenes and Micrococcus luteus,respectively, as well as against other Gram-positive bacteria. Meanwhile, the bacteriocinencoded in the blp cassette was shown to be active against pneumococci, mediating intraspeciescompetition. This report highlights the potential of L. agilis C7 for the production ofbacteriocins inhibiting pathogenic bacteria.
참고문헌 (10)
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