항혈소판 응집 억제제(ASTRIX, PLAVIX) 복약 이후 하지 혈종 발생 사례 보고
A Case Report of Hematoma in the Lower Extremity Induced by Anti-platelet Agents (Astrix, Plavix)
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective: Our aim was to report a case of hematoma in the lower extremity induced by anti-platelet agents (Astrix, Plavix). Methods: The patient was prescribed anti-platelet agents and a hematoma occurred three times in the lower extremity. Before admission, the hematoma had occurred in the lateral compartment area of left lower extremity (2×2 cm). We detected a spontaneous hematoma in the lateral compartment area of right lower extremity (8×4 cm) and we stopped the Astrix medication. We also used herbal medicine (大黃左經湯加味方 ( Daehwangjwagyeong-tang-gami )), external therapy of 大黃梔子 (Dae-hwang-Chi-ja) powder, and wet cupping therapy. We then detected a spontaneous hematoma in the posterior compartment area of the left lower extremity (5×5 cm) and we stopped the Plavix medication. We also used herbal medicine and external therapy. Results: After cessation of the anti-platelet agents (Astrix, Plavix), no recurrence of hematoma was observed in lower extremity and there was no recurrence of cerebral infarction. Conclusions: When anti-platelet agents are administered, attention should be paid to the patient's age and adverse events of the drugs. Bleeding symptoms and adverse effects should be continuously monitored.
Abstract
Objective: Our aim was to report a case of hematoma in the lower extremity induced by anti-platelet agents (Astrix, Plavix). Methods: The patient was prescribed anti-platelet agents and a hematoma occurred three times in the lower extremity. Before admission, the hematoma had occurred in the lateral compartment area of left lower extremity (2×2 cm). We detected a spontaneous hematoma in the lateral compartment area of right lower extremity (8×4 cm) and we stopped the Astrix medication. We also used herbal medicine (大黃左經湯加味方 ( Daehwangjwagyeong-tang-gami )), external therapy of 大黃梔子 (Dae-hwang-Chi-ja) powder, and wet cupping therapy. We then detected a spontaneous hematoma in the posterior compartment area of the left lower extremity (5×5 cm) and we stopped the Plavix medication. We also used herbal medicine and external therapy. Results: After cessation of the anti-platelet agents (Astrix, Plavix), no recurrence of hematoma was observed in lower extremity and there was no recurrence of cerebral infarction. Conclusions: When anti-platelet agents are administered, attention should be paid to the patient's age and adverse events of the drugs. Bleeding symptoms and adverse effects should be continuously monitored.
참고문헌 (21)
- 김종득, "급성기 허혈성 뇌중풍 환자의 한방치료와 한양방협진치료의 임상적 고찰", 동의생리병리학회지, 21(2), pp.543~547 (2007), 한의병리학회
- 김종환, "급성기 뇌졸중 환자의 한양방 협진치료에 대한 임상적 고찰", 대한한방내과학회지, 25(4), pp.65~74 (2004), 대한한방내과학회
- Lee YH, "A Study on the Use of Oriental-Western Integrated Medical Service and Patient Satisfaction", pp.2010
- 박종구, "뇌졸증환자의 한약, 양약 복합 투여에 관한 단면연구", 대한한의학회지, 27(1), pp.1~10 (2006), 대한한의학회
- 박수진, "국내 한약-양약 상호작용 연구논문 분석을 통한 상호작용 정보 현황파악 및 제공방안에 대한 연구", 동의생리병리학회지, 24(4), pp.543~552 (2010), 한의병리학회
- 조한진, "허혈성 뇌졸중의 이차예방을 위한 항혈전제 치료", 뇌신경재활, 7(2), pp.76~85 (2014), 대한뇌신경재활학회
- 조수진, "항혈소판제의 선택을 위하여 고려할 점", Korean Journal of Family Medicine, 27(1), pp.1~6 (2006), 대한가정의학회
- Cakar MA, "Clopidogrel-induced spontaneous pectoral hematoma", Indian journal of pharmacology, 44(4), pp.526~527 (2012)
- Jae Hoon Sung, "Clopidogrel-induced Spontaneous Spinal Epidural Hematoma", Journal of Korean Medical Science, 22(3), pp.577~579 (2007), 대한의학회
- 정일민, "교통사고로 발생한 외상성 대퇴부 피하혈종의 한의학 치료 효과", 한방재활의학과학회지, 20(2), pp.219~225 (2010), 한방재활의학과학회
- Antithrombotic Trialists' Collaboration, "Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients", BMJ (Clinical research ed), 324(7329), pp.71~86 (2002)
- 천상명, "항혈소판제제에 따른 뇌경색 환잔의 혈소판 응집력의 차이", 대한신경과학회지, 22(1), pp.11~15 (2004), 대한신경과학회
- 전성만, "급성기 뇌경색에서의 Clopidogrel의 저항성", 대한신경과학회지, 24(4), pp.319~323 (2006), 대한신경과학회
- 김철우, "아스피린 및 비스테로이드성 항염증제 과민반응", 대한내과학회지, 87(6), pp.659~664 (2014), 대한내과학회[DOI]
- 정우진, "하지 봉와직염에서 발생한 심부정맥 혈전증 1예", 대한내과학회지, 86(3), pp.334~338 (2014), 대한내과학회[DOI]
- Heo J, "Donguibogam", pp.787~788 (2010), Donguibogam Publisher
- Society KAM, "The Acupuncture and Moxibustion", pp.1066~1243 (1998), Jipmoondang
- Lee GJ, "Dong Ssi Chim Gu Bang Hyeol Yo Beop(Dong Ssi Acupuncture and Venesection Therapy)", pp.4~14 (1994), Won Ji Seo Guk
- 김성중, "膻中穴(CV17) 습부항요법이 정상 성인의 심박변이도(HRV)에 미치는 영향", Journal of Acupuncture Research, 30(4), pp.15~24 (2013), 대한침구의학회[DOI]
- Lee SH, "The Effect of Wet Cupping Therapy on the temperature change of body surfaces with Low Back Pain", pp.2007
- 김광일, "항혈소판제 복용 중 발생한 구불결장의 자발성 장벽내 혈종 1예", Clinical Endoscopy, 42(6), pp.397~400 (2011), 대한소화기내시경학회