항응고제 치료에도 임상증상이 호전되지 않은 뇌경색 후 심부정맥혈전증에 대한 한의 치험 1례
A Case Report of Korean Medicine Treatment on Clinical Symptoms in a Patient with Post-stroke Deep Vein Thrombosis
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초록
This case report shows the effect of Korean medicine treatment in a patient with deep vein thrombosis (DVT) after cerebral infarction who is suspected of having post-thrombotic syndrome (PTS) due to the loss of thrombus after receiving new oral anticoagulant (NOAC) treatment. The patient was treated with Korean medicine (Boyanghwano-tang and Hyulbuchuko-tang) three times a day. Acupuncture, moxibustion, infrared, and extra-physical therapy were given to the patient for 24 days. Clinical assessment - grading of edema and circumference of the left lower extremity were observed twice a week until the end of the treatment. NOAC treatment was continued for 24 days. After treatment, the patient’s edema grade and circumference of the extremity improved. On the 24th day, the patient’s chief complaints improved, and she requested termination of treatment. The results suggest that Korean medicine treatments, including Boyanghwano-tang, Hyulbuchuko-tang, and acupuncture therapy, can be effective in improving the clinical symptoms of DVT and PTS.
Abstract
This case report shows the effect of Korean medicine treatment in a patient with deep vein thrombosis (DVT) after cerebral infarction who is suspected of having post-thrombotic syndrome (PTS) due to the loss of thrombus after receiving new oral anticoagulant (NOAC) treatment. The patient was treated with Korean medicine (Boyanghwano-tang and Hyulbuchuko-tang) three times a day. Acupuncture, moxibustion, infrared, and extra-physical therapy were given to the patient for 24 days. Clinical assessment - grading of edema and circumference of the left lower extremity were observed twice a week until the end of the treatment. NOAC treatment was continued for 24 days. After treatment, the patient’s edema grade and circumference of the extremity improved. On the 24th day, the patient’s chief complaints improved, and she requested termination of treatment. The results suggest that Korean medicine treatments, including Boyanghwano-tang, Hyulbuchuko-tang, and acupuncture therapy, can be effective in improving the clinical symptoms of DVT and PTS.
참고문헌 (42)
- 김영환, "하지 심부 정맥 혈전증의 진단과 치료: 한국형 진료지침", 대한영상의학회지, 75(4), pp.233~262 (2016), 대한영상의학회[DOI]
- Bagot CN, "Virchow and His Triad : A Question of Attribution", Br J Haematol, 143(2), pp.180~190 (2008)
- Ocak G, "Risk of Venous Thrombosis in Patients with Major Illnesses : Results from the MEGA Study", J Thromb Haemost, 11(1), pp.116~123 (2013)
- Goldhaver SZ, "Risk Factors for Venous Thromboembolism", J Am Coll Cardiol, 56(1), pp.1~7 (2010)
- Kahn SR, "Clinical Prediction of Deep Vein Thrombosis in Patients with Leg Symptoms", Thromb Haemost, 81(3), pp.353~357 (1999)
- Kwun WH, "Chronic Venous Insufficiency after Deep Vein Trhombosis : Post-thrombotic(Postphlebitic)Syndrome", J Korean Soc Phlebol, 3(1), pp.8~11 (2004)
- 김양기, "정맥혈전증의 최신 치료: 항응고치료를 중심으로", 대한내과학회지, 84(5), pp.659~669 (2013), 대한내과학회[DOI]
- Yoon NS, "Anticoagulation Treatment Using NOAC in Patients with Venous Thromboembolism", Int J Arrhythm, 17(1), pp.36~40 (2016)
- Song C, "Treatment Duration of Deep Venous Thrombosis", Ann Phlebology, 17(1), pp.1~7 (2019)
- Kearon C, "Antithrombotic Therapy for VTE Diseases CHEST Guideline and Expert Panel Report", Chest, 149(2), pp.315~352 (2016)
- Sul JU, "Clinical Investigation about Suspected the DVT(Deep Vein Thrombosis) : Case Report", J Oriental Rehab Med, 14(2), pp.137~145 (2004)
- Min BK, "Clinical Investigation about Deep Vein Thrombosis after Cystostomy : Case Report", The Journal of the Korea Institute of Oriental Medical Informatics, 11(2), pp.14~22 (2005)
- 김태환, "심부정맥혈전증으로 인한 少陽人 下肢浮腫 치험 1례", 사상체질의학회지, 18(3), pp.202~209 (2006), 사상체질의학회
- 강지석, "뇌출혈로 항응고제 사용이 불가능한 심부 정맥혈전증에 대한 혈부축어탕 치험례", 대한한방내과학회지, 30(2), pp.438~449 (2009), 대한한방내과학회
- Kim CG, "Deep Vein Thrombosis after Total Knee Replacement in a Patients undergoing Korean Medical Rehabilitation", J Korean Med Rehab, 25(2), pp.197~203 (2015)
- 김현태, "한의학적 치료로 호전된 심부 정맥혈전증 치험 1례", 동의생리병리학회지, 29(6), pp.503~509 (2015), 한의병리학회[DOI]
- 이명화, "심부정맥혈전증에 대한 혈부축어탕의 치험 1례", 대한한방내과학회지, 37(2), pp.315~321 (2016), 대한한방내과학회
- 오지원, "太陰人 胃脘寒病으로 진단한 하지 부종 및 위약감을 호소하는 심부정맥혈전증 여환 1례", 사상체질의학회지, 29(2), pp.202~209 (2017), 사상체질의학회[DOI]
- 배고은, "지주막하 출혈 후 발생한 심부정맥 혈전증 환자에 대한 한양방 병용치료 증례 보고 1례", 대한한방내과학회지, 39(2), pp.165~175 (2018), 대한한방내과학회
- 김미경, "하지 심부정맥혈전증으로 인한 부종 및 통증에 계지복령환 투약과 침 요법을 포함한 한의 치료를 시행한 증례 1례 보고", 대한한의학회지, 42(2), pp.107~119 (2021), 대한한의학회
- Brodovicz KG, "Reliability and Feasibility of Methods to Quantitatively Assess Peripheral Edema", Clin Med Res, 7(1-2), pp.21~31 (2009)
- Yale SH, "Approach to Diagnosing Lower Extremity Edema", Comp Ther, 27(3), pp.242~252 (2001)
- 김민욱, "심부정맥혈전증의 진단 및 인터벤션 치료", 대한영상의학회지, 78(6), pp.363~370 (2018), 대한영상의학회[DOI]
- Association of Korean Medicine Professors for Cardiovascular and Neurological Medicine, "Cardiovascular and Neurological Medicine in Korean Medicine I", pp.181~189 (2018), WOORI Medical Books
- 박미선, "瘀血證의 임상 질환 범위에 대한 고찰", 대한한의학 방제학회지, 21(1), pp.1~15 (2013), 대한한의학방제학회
- Wang CI, "Uirimgaechak", pp.85~86 (1991), Iljungsa
- Duan M, "Effect of Buyang Haunwu Decoction and Rivaroxaban in prevention of deep vein thrombosis after hip fracture", Modern Journal of Integrated Traditional Chinese and Western Medicine, 27(19), pp.2077~2079 (2018)
- Park SY, "The Effects of Boyanghwanotang on the Thrombosis Related Factors", Korean J Orient Int Med, 21(5), pp.829~837 (2000)
- Kim KD, "Study on the Effect of Boyanghwanotang on Thrombosis and Elevated Blood Viscosity", Korean J Oriental Physiology & Pathology, 3, pp.30~46 (1988)
- Shen J, "Buyang Huanwu Decoction Promotes Angiogenesis after Cerebral Ischemia by Inhibiting the Nox4", ROS Pathway, 2020, pp.2020, 1~14
- Zhou L, "Herbal Complex Buyang Huanwu Tang Improves Motor Endplate Function of Denervated-dependent Skeletal Muscle Atrophy in Rat", J Integr Neurosci, 19(1), pp.89~99 (2020)
- Liu B, "The Atherosclerosis-ameliorating Effects and Molecular Mechanisms of Buyanghuanwu Decoction", Biomed Pharmacother, 123, pp.1~13 (2020)
- Gu Y, "Effects of Jiawei Xuefu Zhuyu Decoction Combined with Rivaroxaban on Deep Vein Thrombosis after Total Knee Replacement Patients", Journal of Traditional Chinese Medicine, 59(18), pp.1578~1582 (2018)
- Kim YS, "The Effects of Hyulbuchukotang(HCE)on the Thrombosis Related Factors", Korean J Orient Int Med, 21(5), pp.819~827 (2000)
- 임현정, "血府逐瘀湯加味方의 抗血栓作用에 대한 實驗的 硏究", 대한한방부인과학회지, 21(1), pp.117~133 (2008), 대한한방부인과학회
- Liang B, "Systematic Pharmacology and GEO Database Mining Revealed the Therapeutic Mechanism for Atherosclerosis Cardiovascular Disease", Front Cardiovasc Med, 7, pp.1~14 (2020)
- Frishman WH, "Effects of Nonsteroidal Anti-Inflammatory Drug Therapy on Blood Pressure and Peripheral Edema", Am J Cardiol, 89(6), pp.18~25 (2002)
- Cabassi A, "Non-steroidal Anti-inflammatory Drug Effects on Renal and Cardiovascular Function : From Physiology to Clinical Practice", Eur J Prev Cardiol, 27(8), pp.850~867 (2020)
- Fujioka M, "Eperisone, an Antispastic Agent, Possesses Vasodilating Actions on the Guinea-pig Basilar Artery", J Pharmacol Exp Ther, 235(3), pp.757~763 (1985)
- Sakai Y, "The Effect of Muscle Relaxant on the Paraspinal Muscle Blood Flow", Spine, 33(6), pp.581~587 (2008)
- Inonue S, "Mechanisms of Action of Eperisone on Isolated Dog Saphenous Arteries and Veins", Japan J Pharmacol, 50(3), pp.271~282 (1989)
- Sica DA, "Alpha1-Adrenergic Bloackers : Current Usage Considerations", J Clin Hypertens, 7(12), pp.757~762 (2005)
