Anti-arteriosclerotic and Anti-hyperlipidemic Effects of Sea Mustard (Undaria pinnatifida) in Sprague-Dawley rats
4
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
This study investigated the inhibitory effects of sea mustard on high-fat diet-induced obesity and hyperlipidemia in Sprague-Dawley rats. Sea mustard (Undaria pinnatifida) powder, sea mustard ethanol extract, and sea mustard ethanol-extracted residue were tested. The ethanol extracted residue had the most beneficial anti-hyperlipidemic activity. Alginate in the sea mustard was considered to be the key component. The ethanol-extracted residue of sea mustard also had antioxidant activity, which may be effective in preventing hyperlipidemia by increasing the enzymatic activity of superoxide dismutase, which can remove active oxygen from the bloodstream.
Abstract
This study investigated the inhibitory effects of sea mustard on high-fat diet-induced obesity and hyperlipidemia in Sprague-Dawley rats. Sea mustard (Undaria pinnatifida) powder, sea mustard ethanol extract, and sea mustard ethanol-extracted residue were tested. The ethanol extracted residue had the most beneficial anti-hyperlipidemic activity. Alginate in the sea mustard was considered to be the key component. The ethanol-extracted residue of sea mustard also had antioxidant activity, which may be effective in preventing hyperlipidemia by increasing the enzymatic activity of superoxide dismutase, which can remove active oxygen from the bloodstream.
참고문헌 (50)
- Akiba Y, "Effects of dietary fiver on lipie metabolism in liver and adipose tissue in chicks", J Nut, 112, pp.1577~1585 (1982)
- Anderson JW, "Sort-chain fatty acid fermentation products of plant fiver after glucose metabolism of isolated rat hepatocytes", Proc Soc Exp Biol Med, 177, pp.372~376 (1984)
- Anderson JW, "Hypocholes-terolemic effects of bean products", Am J Clin Nutr, 48, pp.749~753 (1988)
- Anderson JW, "Dietary fiber : Hyperlipidemia, hypertension, and coronary heart disease", Am J Gastroent, 81, pp.907~919 (1986)
- Celik S, "Influence of vitamin E on the levels of fatty acids and MDA in sometisues of diabetic rats", Cell Biochem Funct, 20, pp.67~71 (2002)
- Chen PS, "Microdetermination of phosphorus", Anal Chem Vol, pp.1756~1760 (1956)
- Chen WJ, "Effects of guar gum and wheat bran on lipid metabolism in rat", J Nutr, 109, pp.1028~1034 (1979)
- Choi JH, "Studies on Anti-aging Action of Brown Algae (Undaria pinnatifida) 1. Dose Effect of Alginic Acid as a Modulator of Anti-aging Action in Serum Lipids", Korean J Gerontology, 1, pp.173~178 (1991)
- Cho KJ, "Antitumor Effect and Immunology Activity of Seaweeds toward Sarcoma-180", Bull Korean Fish Soc, 23, pp.345~352 (1990)
- 조영자, "미역첨가 식이가 당뇨 유발쥐의 혈청지질과 혈당 및 항산화 효소에 미치는 영향", 한국식품영양과학회지, 33(6), pp.987~994 (2004), 한국식품영양과학회
- Choi YS, "Effects of Alcohol Consumption and Fat Content in Diet on Growth, Hepatic Function and Biochemical Indices of Blood in Rat", Korean J Nutr, 20, pp.432~441 (1987)
- Chung KH, "Effects of Alcohol Consumption and Fat Content in Diet on Chemical Composition and Morphology of Liver in Rat", Korean J Nutr, 21, pp.154~163 (1988)
- Fernandez ML, "Pectin isolated from prickly pear(Opuntiasp.)modifies low density lipoprotein metabolism in cholesterol-fed guinea pigs", J Nutr, 120, pp.1238~1290 (1990)
- Folch J, "A simple method for the isolation and purification of total lipids from animal tissues", J Biol Chem, 226, pp.497~509 (1957)
- Friedwald WT, "Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without was of the preparative ultracentrifuge", Clin Chem, 18, pp.499~506 (1972)
- Fringe CS, "The Colormetric method for determination of serum total lipids based on the sulfo-phosphanilli reaction", J clin pathol, 52, pp.82~92 (1980)
- George VV, "Effects of cholesterol absorption, synthesis and metabolism in the rats", Am J Chin Nutr, 33, pp.2182~2191 (1982)
- Goode GK, "Hyper-lipidemia, hypertension and coronary heart diseare", Lancet, 345, pp.362~364 (1995)
- Hong YK, "Effect of the Seaweed Porphya yezoensis Extract on Triton WR-1339 Induced Hypercholesterolemia in Mouse", J Korean Fish Soc, 31, pp.508~515 (1998)
- Jang SJ, "Effects of Dietary Fiber Sources and Levels on Lipid Metabolism in Rats fed High Lard Diet", Korean J Nutr, 28, pp.107~114 (1995)
- Kang HJ, "Effects of Sodium Alginate and Cellulose on Postprandial Plasma Lipoprotein and Cholesterol Metabolism in Rats (I)", J Korean Soc Food Nutr, 23, pp.887~893 (1994)
- Keith ES, "Atherosclerosis", Encyclo Human Bio, 1, pp.447~455 (1991)
- Kim HS, "Effects of the Feeding Hijikia fusiforme(Harvey) Okamura on Lipid Composition of Serum in Dietary Hyperlipidemic Rats", J Korean Soc Food Sci Nutr, 27, pp.718~723 (1998)
- Kim KH, "Optimum Conditions for Extracting Alginic Acid from Undaria Pinnatifida and Amino Acid Composition of Its Extraction Residue", Korean J Food Sci Technol, 16, pp.336~340 (1984)
- Kim KH, "Studies on the Manufacture of Underia pinnatifida Laver and it's Physicochemical Properties - I. Histochemical Properties", Korean J Food Sci Technol, 14, pp.336~341 (1982)
- Kim SH, "Determination and physical properties of dietary fiber in seaweed products", J Korean Soc Food Nutr, 17, pp.324~325 (1988)
- Kobatake Y, "Influence of fish consumption on serum lipid and lipid peroxide concentrations in middle aged subjects", J Japan Soc Nutr & Food Sci, 40, pp.103~110 (1987)
- Lee HS, "A Study on the development of high-fiber supplements for the diabetic patients (I) -Effect of Seaweed Supplementation on the Gastrointestinal Function and Diabetic Symptom Control in Streptozotocin-induced Diabetic Rats", Korean J Nutr, 29, pp.286~295 (1996)
- Lee HS, "A Study on the development of high-fiber supplements for the diabetic patients (II) -Effect of Seaweed Supplementation on the Gastrointestinal Function and Diabetic Symptom Control in Streptozotocin-induced Diabetic Rats-", Korean J Nutr, 29, pp.296~306 (1996)
- Lee HS, "A Study on the development of high-fiber supplements for the diabetic patients (II) Effect of Seaweed Supplymentation on the Lipid and Glucose Meta-bolism in Streptozotocin-induced Diabetic Rats", Korean J Nutr, 29, pp.296~306 (1996)
- Lowry OH, "Protein measurement with the folin phenol reagent", J Biol Chem, 193, pp.265~265 (1951)
- Maeda H, "Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues", Bio-chemical and Biophysical Research Communications, 332, pp.392~397 (2005)
- Mc Gowan MW, "Aperoxidase -coupled method for the colorimetric determination of serum triglycerides", Clin Chem, 29, pp.538~538 (1983)
- Noma A, "High-density lipoprotein cholesterol levels of very old people in the diagnosis of dementia", Oxford Journals, 15, pp.267~270 (1986)
- Nishina PM, "Effects of propionate on lipid bipsyntheses in isolated rat hepatocyres", J Nutr, 120, pp.668~673 (1990)
- Oyanagui Y, "Reevaluation of assay methods and establishment of kit for superoxide dismutase activity", Anal Biochem, 42, pp.290~296 (1984)
- Park JC, "Effect of Methanolic Extract of Pachymeniopsis elliptica on Lipids Component of Hyperlipidemic Rats", J Korean Soc Food Sci Nutr, 25, pp.958~962 (1996)
- Park SH, "The Effect of Dietary Fiber Feeding on Gastrointestinal Functions and Lipid and Glucose Metabolism in Streptozotocin-induced Diabetic Rats", Korean J Nutr, 27, pp.311~322 (1994)
- Richmond W, "Use of cholesterol oxidase for assay of total and free cholesterol in serum by continuous flow analysis", Clin Chem, 22, pp.1579~1579 (1976)
- Sato M, "Angiotensin I-converting enzyme inhibitory peptides derived from` Wakame (Undaria pinnatifida) and their antihypertensive effect in spontaneously hypersensitive rats", J Agtic Food Chem, 50, pp.6245~6252 (2002)
- Schrijver R, "Cholesterollowwering effects and utillization of protein, lipid, fiver and energy in rats fed unprocessd and baked oat bran", J Nutr, 122, pp.1318~1324 (1992)
- Spiller GA, "Dietary fiber in human nutrition, Crit. Rev", Food Sci Nutr, 7, pp.39~66 (1975)
- Story JA, "The role of dietary fiber in lipid metabolism", Adv Lipid Res, 18, pp.229~246 (1981)
- Suetsuna K, "Anti-hypertensive effects of Undaria pinnatifida (Wakame) peptide on blood pressure on spontaneously hyper-tensive rats", J Nutr Biochem, 15, pp.267~272 (2004)
- Tsai AC, "influence of certain dietary fibers in serum and tissue cholesterol levels in rats", P J Nutr, 106, pp.118~123 (1976)
- Velthuis-te Wierik EJ, "Consumption of reduced-fat products : Effects in parameters of antioxidative capacity", Eur J Clin Nutr, 50, pp.214~219 (1996)
- Yagi K, "Lipid peroxides and human diseases", Chemistry and Physics of Lipids, 45, pp.337~342 (1987)
- Yamamoto L, "Antitumour effect of seaweeds: III. Antitumour effect of extracts from Sargassum", Jap J Exp Med, 51, pp.187~189 (1981)
- Yamamoto L, "Antitumor activity of edible marine algae: Effect of crude fucoidan fraction prepared from edible brown sea weeds L-1210 leukemia", Hydro-biologia, 116, pp.145~150 (1984)
- Yang JL, "Effects of Dietary Fibers on Cholesterol Metabolism in Cholesterol-Fed Rats", J Korean Soc Food Nutr, 25, pp.392~398 (1996)
