A Case of Metachronous Metastasis to the Breast from Non-Small Cell Lung Carcinoma
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Breast metastases from an extramammary primary tumor are very rare and the prognosis for such patients is generally poor. We report here on a case of a 42-year-old female with metastasis of non-small cell lung cancer to the breast, and she is now being followed up on an outpatient basis. In 2004, she presented with a solitary pulmonary nodule in the left lung, and this lesion had been noted to have gradually increased in size over time. The final pathological diagnosis was adenocarcinoma, and the diagnosis was made by performing percutaneous needle aspiration and lobectomy of the left upper lobe. Adjuvant chemotherapy and radiotherapy were given. Unfortunately, a nodule in the left breast was noted three years later, and metastatic non-small-cell lung cancer to the breast was diagnosed by excisional biopsy. Making the correct diagnosis to distinguish a primary breast carcinoma from a metastatic one is important, because the therapeutic plan and outcome for these two types of cancer are quite different.
Abstract
Breast metastases from an extramammary primary tumor are very rare and the prognosis for such patients is generally poor. We report here on a case of a 42-year-old female with metastasis of non-small cell lung cancer to the breast, and she is now being followed up on an outpatient basis. In 2004, she presented with a solitary pulmonary nodule in the left lung, and this lesion had been noted to have gradually increased in size over time. The final pathological diagnosis was adenocarcinoma, and the diagnosis was made by performing percutaneous needle aspiration and lobectomy of the left upper lobe. Adjuvant chemotherapy and radiotherapy were given. Unfortunately, a nodule in the left breast was noted three years later, and metastatic non-small-cell lung cancer to the breast was diagnosed by excisional biopsy. Making the correct diagnosis to distinguish a primary breast carcinoma from a metastatic one is important, because the therapeutic plan and outcome for these two types of cancer are quite different.
참고문헌 (14)
- Greenlee RT, "Cancer statistics, 2001", CA Cancer J Clin, 51, pp.15~36 (2001)
- Abrams HL, "Metastases in carcinoma; analysis of 1000 autopsied cases", Cancer, 3, pp.74~85 (1950)
- Quint LE, "Distribution of distant metastases from newly diagnosed non-small cell lung cancer", Ann Thorac Surg, 62, pp.246~250 (1996)
- Rosen PP, "Metastases in the breast from nonmammary malignant neoplasm in Rosen’s pathology of the breast. 2nd ed", pp.689~707 (2001), Lippincott Williams & Wilkins
- Yeh CN, "Clinical and ultrasonographic characteristics of breast metastases from extramammary malignancies", Am Surg, 70, pp.287~290 (2004)
- Toombs BD, "Metastatic disease to the breast: clinical, pathologic, and radiographic features", AJR Am J Roentgenol, 129, pp.673~676 (1977)
- Sheen-Chen SM, "Metastatic malignant pleural mesothelioma to the breast", South Med J, 99, pp.1395~1397 (2006)
- Sheen-Chen SM, "Metastatic rhabdomyosarcoma to the breast", Anticancer Res, 25, pp.527~529 (2005)
- Sneige N, "Fine-needle aspiration cytology of metastatic neoplasms in the breast", Am J Clin Pathol, 92, pp.27~35 (1989)
- Chaignaud B, "Diagnosis and natural history of extramammary tumors metastatic to the breast", J Am Coll Surg, 179, pp.49~53 (1994)
- Bohman LG, "Breast metastases from extramammary malignancies", Radiology, 144, pp.309~312 (1982)
- Pelosi G, "Immunoreactivity for thyroid transcription factor-1 in stage I non-small cell carcinomas of the lung", Am J Surg Pathol, 25, pp.363~372 (2001)
- Ordóñez NG, "Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas", Adv Anat Pathol, 7, pp.123~127 (2000)
- Harlamert HA, "Thyroid transcription factor-1 and cytokeratins 7 and 20 in pulmonary and breast carcinoma", Acta Cytol, 42, pp.1382~1388 (1998)