Successful Treatment of Intractable Bleeding Caused by Radiation-Induced Hemorrhagic Gastritis Using Oral Prednisolone: A Case Report
3
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Radiation-induced hemorrhagic gastritis is an intractable and dangerous condition. We describe a 59-year-old female patient with radiation-induced hemorrhagic gastritis. The patient underwent postoperative radiation therapy with a dose of 54 Gy in 30fractions after a radical operation for a Klatskin tumor. Radiation volume includedthe gastric antrum. Approximately three months after radiation therapy, she wasadmitted for melena and anemia. Esophagogastroduodenoscopy showed an area ofbleeding in the gastric antrum that was so diffuse that effective laser coagulation wasnot feasible. After failure of various treatments and transfusion of 7,040 mL of packedred blood cells, we successfully stopped the hemorrhage using oral prednisolonetreatment. Based on this case, we think that oral prednisolone treatment can be triedas a first treatment for potentially life-threatening radiation-induced hemorrhagicgastritis.
Abstract
Radiation-induced hemorrhagic gastritis is an intractable and dangerous condition. We describe a 59-year-old female patient with radiation-induced hemorrhagic gastritis. The patient underwent postoperative radiation therapy with a dose of 54 Gy in 30fractions after a radical operation for a Klatskin tumor. Radiation volume includedthe gastric antrum. Approximately three months after radiation therapy, she wasadmitted for melena and anemia. Esophagogastroduodenoscopy showed an area ofbleeding in the gastric antrum that was so diffuse that effective laser coagulation wasnot feasible. After failure of various treatments and transfusion of 7,040 mL of packedred blood cells, we successfully stopped the hemorrhage using oral prednisolonetreatment. Based on this case, we think that oral prednisolone treatment can be triedas a first treatment for potentially life-threatening radiation-induced hemorrhagicgastritis.
참고문헌 (14)
- Sang Min Yoon, "Radioresponse of Hepatocellular Carcinoma-Treatment of Lymph Node Metastasis", Cancer Research and Treatment, 36(1), pp.79~84 (2004), 대한암학회
- Emami B, "Tolerance of normal tissue to therapeutic irradiation", Int J Radiat Oncol Biol Phys, 21, pp.109~122 (1991)
- Kernstine KH, "Hyperbaric oxygen treatment of hemorrhagic radiation-induced gastritis after esophagectomy", Ann Thorac Surg, 80, pp.1115~1117 (2005)
- Banerjee N, "Hyperbaric oxygen therapy : an adjuvant treatment modality for chemo-radiation induced hemorrhagic gastritis", Trop Gastroenterol, 32, pp.248~250 (2011)
- Shukuwa K, "Argon plasma coagulation therapy for a hemorrhagic radiationinduced gastritis in patient with pancreatic cancer", Intern Med, 46, pp.975~977 (2007)
- Furukawa K, "A case of radiation hemorrhagic gastritis successfully treated by endoscopic argon plasma coagulation", Endosc Forum Dig Dis, 19, pp.40~44 (2003)
- Wada S, "Endoscopic hemostasis for radiation-induced gastritis using argon plasma coagulation", J Gastroenterol Hepatol, 18, pp.1215~1218 (2003)
- Staiano T, "Treatment of radiation-induced hemorrhagic gastritis with endoscopic band ligation", Gastrointest Endosc, 72, pp.452~453 (2010)
- Flobert C, "Severe hemorrhagic gastritis of radiation origin", Gastroenterol Clin Biol, 22, pp.232~234 (1998)
- Yeung YP, "Surgical treatment of recalcitrant radiation-induced gastric erosions", Head Neck, 22, pp.303~306 (2000)
- Inaba K, "Hemorrhagic radiation gastritis after chemoradiation therapy for peritoneal lymph node metastasis of esophageal carcinoma successfully treated with repeated intraarterial steroid infusions", Esophagus, 4, pp.67~72 (2007)
- Zhang L, "Treatment of radiation-induced hemorrhagic gastritis with prednisolone : a case report", World J Gastroenterol, 18, pp.7402~7404 (2012)
- Toda K, "Therapeutic effect of intraarterial prednisolone injection in severe intestinal Behcet's disease", J Gastroenterol, 37, pp.844~848 (2002)
- Indaram AV, "Mucosal cytokine production in radiation-induced proctosigmoiditis compared with inflammatory bowel disease", Am J Gastroenterol, 95, pp.1221~1225 (2000)