Biology of SNU Cell Lines
1
조회
0
다운로드
9
인용
0
참고문헌
초록
Abstract
SNU (Seoul National University) cell lines have been established from Korean cancer patients since 1982. Of these 109 cell lines have been characterized and reported, i.e., 17 colorectal carcinoma, 12 hepatocellular carcinoma, 11 gastric carcinoma, 12 uterine cervical carcinoma, 17 B-lymphoblastoid cell lines derived from cancer patients, 5 ovarian carcinoma, 3 malignant mixed Mllerian tumor, 6 laryngeal squamous cell carcinoma, 7 renal cell carcinoma, 9 brain tumor, 6 biliary tract, and 4 pancreatic carcinoma cell lines. These SNU cell lines have been distributed to biomedical researchers domestic and worldwide through the KCLB (Korean Cell Line Bank), and have proven to be of value in various scientific research fields. The characteristics of these cell lines have been reported in over 180 international journals by our laboratory and by many other researchers from 1987. In this paper, the cellular and molecular characteristics of SNU human cancer cell lines are summarized according to their genetic and epigenetic alterations and functional analysis.
참고문헌 (98)
- "Basic Principles of Cancer Cell Culture Methods in Molecular Medicine", pp.3~15 (2004)
- "Characteristics of cell lines established from humangastric carcinoma", 50, pp.2773~80 (1990)
- "Characterization of cell lines established from human hepatocellularcarcinoma", 62, pp.276~82 (1995)
- "Characteristics of cell lines established fromhuman colorectal carcinoma", 47, pp.6710~8 (1987)
- "Establishment and characterization of human gastric carcinomacell lines", 70, pp.443~9 (1997)
- "Establishment and characterization of 12 human colorectalcarcinomacell lines", 81, pp.902~10 (1999)
- "Establishmentand characterization of four human hepatocellular carcinomacell lines containing hepatitis B virus DNA", 5, pp.289~95 (1999)
- "Establishmentand characterization of 12 uterine cervical-carcinoma cell lines common sequence variation in the", pp.313~20 (1997)
- "B-lymphoblastoid cell lines from cancer patients", 34, pp.97~100 (1998)
- "Establishment and characterization of human ovarian carcinomacell lines", 66, pp.378~87 (1997)
- "Establishment and characterization of cell lines derivedfrom uterine malignant mixed Mullerian tumor", 66, pp.464~74 (1997)
- "Establishmentand characterization of human laryngeal squamouscell carcinoma cell lines", 109, pp.976~82 (1999)
- "Establishment and characterization of seven human renal cellcarcinoma cell lines", 85, pp.130~8 (2000)
- "Establishment and characterization of nine human brain tumorcell lines", 37, pp.625~8 (2001)
- "Establishment and characterisation of six human biliarytract cancer cell lines", 87, pp.187~93 (2002)
- "Establishment and characterization of four human pancreaticcarcinoma cell lines Genetic alterations in the TGFBR2gene but not in the MADH4 gene", pp.205~14 (2002)
- "Identification of genes with differential expression in acquireddrug-resistant gastric cancer cells using high-density oligonucleotidemicroarrays", 10, pp.272~84 (2004)
- "Characteristics of human gastric carcinoma cell lines with inducedmultidrug resistance", 17, pp.3531~6 (1997)
- "Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistancein a human colon cancer cell line", 10, pp.4176~84 (2004)
- "Decreased pyruvate kinase M2 activity linked to cisplatinresistance in human gastric carcinoma cell lines", 108, pp.532~9 (2004)
- "expressionof Bcl-2 and cell cycle regulation in doxorubicinresistant", pp.343~8 (2003)
- "SNU cell lines and their application for cancer", pp.89~98 (2002)
- "Isolation and culture of renal cancercell lines Methods in Molecular Medicine", pp.111~9 (2004)
- "Isolation and culture of colon cancercell lines Methods in Molecular Medicine", pp.79~92 (2004)
- "Culture of normaland malignant gastric epithelium", pp.23~66 (2004)
- "Radiation sensitivity and study of glutathione andrelated enzymes in human colorectal cancer cell lines", 24, pp.1219~24 (1988)
- "Functional interaction of lithocholic acid conjugates withM3 muscarinic receptors on a human colon cancer cell line", 1588, pp.48~55 (2002)
- "Characterizationof functional receptors for gastrointestinal hormoneson human colon cancer cells", 52, pp.1114~22 (1992)
- "Toxicity of levamisole and 5-fluorouracilin human colon carcinoma cells", 81, pp.1413~7 (1989)
- "Determinants of trimetrexate lethality in humancolon cancer cells", 70, pp.1075~84 (1994)
- "Autonomous proliferation of colon cancer cells thatcoexpress transforming growth factor alpha and its receptor Variable effects of receptor-blocking antibody", pp.474~85 (1992)
- "Differentiation of a colon cancer cell line on a reconstitutedbasement membrane in vitro", 79, pp.443~51 (1998)
- "Development and applications of a beta-catenin oligonucleotidemicroarray:beta-catenin mutations are dominantly foundin the proximal colon cancers with microsatellite instability", 9, pp.2920~5 (2003)
- "Mutational analysis of OGG1 MTH1 in FAP R154H OGG1", pp.498~503 (2004)
- "Promoter hypermethylation downregulates RUNX3 geneexpression in colorectal cancer cell lines", 23, pp.6736~42 (2004)
- "Mutations in hMSH6alone are not sufficient to cause the microsatellite instabilityin colorectal cancer cell lines", 35, pp.1724~9 (1999)
- "Pattern of growth factor proto-oncogene andcarcinoembryonic antigen gene expression in human colorectalcarcinoma cell lines", pp.209~14 (1992)
- "Sequencedependentgrowth inhibition and DNA damage formation bythe irinotecan-5-fluorouracil combination in human colon carcinomacell lines", 35, pp.1851~61 (1999)
- "In vitro and in vivo characteristics of a human colon cancercell line,SNU-C5N,expressing sodium-iodide symporter", 29, pp.537~45 (2002)
- "Enhancement of fluorinated pyrimidine- inducedcytotoxicity by leucovorin in human colorectal carcinomacell lines", 80, pp.1560~4 (1988)
- "Biology of colorectal and gastric cancercell lines", 24, pp.131~41 (1996)
- "Chemosensitivity testing of human colorectalcarcinoma cell lines using a tetrazolium-based colorimetric assay", 47, pp.5875~9 (1987)
- "MDR1 gene expression:its effect on drug resistance to doxorubicinin human hepatocellular carcinoma cell lines", 86, pp.700~5 (1994)
- "Oligonucleotide microarray-based mutation detection of theK-ras gene in colorectal cancers with use of competitive DNAhybridization", 50, pp.1688~91 (2004)
- "Chemosensitivitypatterns and expression of human multidrug resistance-associated MDR1 gene by human gastric andcolorectal carcinoma cell lines", 82, pp.193~8 (1990)
- "Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-beta-D-arabinofuranosylcytosine", 42, pp.409~18 (1991)
- "Cellular uptake and antitumor activity of the new anthracyclineanalog DA-125 in human cancer cell lines", 40, pp.23~30 (1997)
- , 1994, 1613~8
- "Detectionand quantitation of thymidylate synthase mRNA inhuman colon adenocarcinoma cell line resistant to 5-fluorouracilby competitive PCR", 18, pp.1457~63 (1998)
- "Metabolism andRNA incorporation of cyclopentenyl cytosine in human colorectalcancer cells", 43, pp.1587~99 (1992)
- "Cytotoxicactivities of acetoxyscirpenediol and ergosterol peroxide fromPaecilomyces tenuipes", 69, pp.229~37 (2001)
- "Synthesis of radioiodine labeled dibenzyl disulfide for evaluationof tumor cell uptake", 12, pp.859~64 (2004)
- "Saucernetin-8 Isolated from Saururus chinensis Induced theDifferentiation of Human Acute Promyelocytic LeukemiaHL-60 Cells", 27, pp.1594~8 (2004)
- "Schedule- dependentin vitro combination effects of methotrexate and 5-fluorouracilin human tumor cell lines", 47, pp.401~7 (1991)
- "Mutations of the Birt-Hogg-Dube gene in sporadiccolorectal carcinomas and colorectal carcinoma", pp.364~7 (2003)
- "Chromogranin A expression in normal and malignanthuman tissues", 82, pp.686~90 (1988)
- "Identification of PDZK4 a novel human gene with", pp.5551~7 (2004)
- "The E-cadherin -347G→GA promoter polymorphism andits effect on transcriptional regulation", 25, pp.895~9 (2004)
- "in the Ecadheringene is associated with colorectal cancer", carci(genesis), pp.2173~6 (2004)
- "Chromogranin-A expression in gastric and colon cancertissues", 51, pp.189~94 (1992)
- "Abnormal methylation of the calcitonin gene inhuman colonic neoplasms", 49, pp.3468~73 (1989)
- "p53 functional loss in a colon cancer cell linewith two missense mutations"
- "Novel transcripts of fibroblast growth factor receptor 3 revealaberrant splicing and activation of cryptic splice sequences incolorectal cancer", 60, pp.4049~52 (2000)
- "Synthesis of 6-aziridinylbenzimidazolederivatives and their in vitro antitumor activities", 21, pp.599~609 (1998)
- "Synthesis and in vitro antitumoractivity of 2-alkyl", pp.2 7 288~301 (2000)
- "Synergistic effect and possible mechanisms of tumornecrosis factor and cisplatin cytotoxicity under moderate hyperthermiaagainst gastric cancer cells", 4, pp.141~8 (1997)
- "TownsendCM Jr. Cyclin-dependent kinase inhibitors block proliferationof human gastric cancer cells" (1997)
- "Caspase-mediated Cdk2 activation is a critical step toexecute transforming growth factor-beta1-induced apoptosis inhuman gastric cancer cells", 20, pp.1254~65 (2001)
- "Essential moiety for antimutagenic and cytotoxic activity ofhederagenin monodesmosides and bisdesmosides isolated fromthe stem bark of Kalopanax pictus", 66, pp.329~32 (2000)
- "Mechanistic aspects of green tea as a cancer preventive:effectof components on human stomach cancer cell lines", 90, pp.733~9 (1999)
- "TNFalpha induces apoptosis mediated by AEBSF-sensitive serineprotease that may involve upstream caspase-3", CPP32, 2000, 1243~8
- "Inhibition of proliferation and induction ofapoptosis in SNU-1 human gastric cancer cells by the plantsulfolipid", sulfoqui(vosyldiacylglycerol), pp.310~5 (2001)
- "CDK4 down-regulation induced by paclitaxel is associatedwith G1 arrest in gastric cancer cells", 4, pp.3063~8 (1998)
- "Effects of buthionine sulfoximine treatment on cellularglutathione levels and cytotoxicities of cisplatin carboplatinand radiation in human stomach and ovarian cancer cell lines", pp.111~7 (1992)
- "Effect of suramin ondifferentiation of human stomach cancer cell lines", 12, pp.433~42 (1997)
- -5 ne derivatives), "3 8 893~900"
- "expression isclosely related to death receptor-4 and -5 induction", carci(genesis), pp.~1 (2004)
- "Synthesis and antitumor activity of a series of [2-substituted-4", ami(methyl), pp.5 3 1471~85 (1994)
- "Pharmacokinetics and antitumor activity of a new platinumcompound", ami(methyl), pp.5 3 1~6 (1995)
- "Cytotoxicity and DNA topoisomerase inhibitory activity ofbenz", pp.9~4 (2003)
- "The cytotoxicity of psoralidin from Psoraleacorylifolia", 62, pp.353~4 (1996)
- "Establishment and characterization of 5-fluorouracil-resistantgastric cancer cells", 159, pp.95~101 (2000)
- "Expressionof transforming growth factor beta type II receptorreduces tumorigenicity in human gastric cancer cells", 57, pp.2856~9 (1997)
- "Transcriptional repression of the transforming growthfactor-beta type I receptor gene by DNA methylation resultsin the development of TGF-beta resistance in human gastriccancer", 18, pp.7280~6 (1999)
- "Rapid induction of p21WAF1 but delayed down-regulation ofCdc 25A in the TGF-beta-induced cell cycle arrest of gastriccarcinoma cells", 80, pp.1144~9 (1999)
- "A transforming growth factor beta receptor type IIgene mutation common in colon and gastric but rare in endometrialcancers with microsatellite instability", 55, pp.5545~7 (1995)
- "Genetic changes in the transforming growth factor beta type II receptor gene in human gastric cancercells correlation with sensitivity to growth inhibition byTGF-beta", pp.8772~6 (1994)
- "Truncation of the TGF-beta type II receptor gene results ininsensitivity to TGF-beta in human gastric cancer cells", 18, pp.2213~9 (1999)
- "Capsaicin can alter the expression of tumor forming-relatedgenes which might be followed by", pp.235~1 41 (1997)
- "Aberrant signaling of TGF-beta1 by the mutant Smad4 ingastric cancer cells", 196, pp.197~206 (2003)
- "Transforming growth factor-beta 1 induces apoptosisthrough Fas ligand-independent activation of the Fas deathpathway in human gastric SNU-620 carcinoma cells", 15, pp.420~34 (2004)
- "Detectionof amplified DNA sequences in human tumor cell lines byfluorescence in situ hybridization", 4, pp.314~20 (1992)
- "Amplification of c-myc and c-met in gastric cancers detection by fluorescence in situ hybridization", pp.1143~53 (1998)
- "Novel DNA sequences at chromosome 10q26 areamplified in human gastric carcinoma cell lines:molecularcloning by competitive DNA reassociation", 19, pp.117~23 (1991)
- "DNA amplification in human gastric carcinomas", 65, pp.111~4 (1993)
- "Increasedsusceptibility of the c-Myc overexpressing cell line", pp.17~16 23 (1998)
- "Post-transcriptional control ofc-erb B-2 overexpression in stomach cancer cells", 33, pp.15~9 (2001)
- "Themechanism of c-erbB-2 gene product increase in stomachcancer cell lines", 8, pp.153~9 (1993)
