Case Series of Different Onset of Skin Metastasis According to the Breast Cancer Subtypes
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We report on five cases of skin metastasis according to the breast cancer (BC)subtype. Two cases of HER2 positive BC showed only skin metastasis after immediatepostoperative period and rapid clinical response to targeted therapy. Another twocases of triple negative BC showed thyroid and lung metastasis in addition to skinmetastasis, and their response of cytotoxic chemotherapy was not definite. The otherhormone positive BC showed skin metastasis only, with a longer, slower, lessprogressive pattern than other subtypes. Most cases of skin metastasis were detectedat terminal stage of malignancy and were considered to have a limited survival period. However, some BC patients can survive longer if the targeted agents are effective. Therefore, physicians should provide detailed follow up of BC after curative treatmentand understand the metastatic pattern of BC according to the subtype.
Abstract
We report on five cases of skin metastasis according to the breast cancer (BC)subtype. Two cases of HER2 positive BC showed only skin metastasis after immediatepostoperative period and rapid clinical response to targeted therapy. Another twocases of triple negative BC showed thyroid and lung metastasis in addition to skinmetastasis, and their response of cytotoxic chemotherapy was not definite. The otherhormone positive BC showed skin metastasis only, with a longer, slower, lessprogressive pattern than other subtypes. Most cases of skin metastasis were detectedat terminal stage of malignancy and were considered to have a limited survival period. However, some BC patients can survive longer if the targeted agents are effective. Therefore, physicians should provide detailed follow up of BC after curative treatmentand understand the metastatic pattern of BC according to the subtype.
참고문헌 (12)
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