Carcinoma Erysipelatoides Resulting from Cutaneous Metastasis of Breast Cancer
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Cutaneous metastasis of breast cancer is easily misdiagnosed. Herein, we report two such cases. In the first case, a 49-year-old woman received neoadjuvant chemotherapy and underwent modified radical mastectomy for right locally advanced breast cancer (LABC). The erythematous skin lesion on the right chest wall was detected during ongoing trastuzumab treatment after radiotherapy. Radiation recall dermatitis was initially suspected, but the lesion persisted for 7 months, and a biopsy confirmed metastatic carcinoma showing multiple lymphatic tumor emboli. In the second case, a 42-year-old woman underwent breast-conserving surgery with axillary lymph node dissection for right LABC, and then adjuvant chemotherapy followed by trastuzumab treatment and radiotherapy. A localized slightly pruritic erythematous patch on the right breast persisted for 2 months, and allergic dermatitis was suspected. However, a 3-cm mass developed in the right breast during trastuzumab treatment, and a biopsy confirmed a diagnosis of ductal carcinoma with multiple lymphatic tumor emboli.
Abstract
Cutaneous metastasis of breast cancer is easily misdiagnosed. Herein, we report two such cases. In the first case, a 49-year-old woman received neoadjuvant chemotherapy and underwent modified radical mastectomy for right locally advanced breast cancer (LABC). The erythematous skin lesion on the right chest wall was detected during ongoing trastuzumab treatment after radiotherapy. Radiation recall dermatitis was initially suspected, but the lesion persisted for 7 months, and a biopsy confirmed metastatic carcinoma showing multiple lymphatic tumor emboli. In the second case, a 42-year-old woman underwent breast-conserving surgery with axillary lymph node dissection for right LABC, and then adjuvant chemotherapy followed by trastuzumab treatment and radiotherapy. A localized slightly pruritic erythematous patch on the right breast persisted for 2 months, and allergic dermatitis was suspected. However, a 3-cm mass developed in the right breast during trastuzumab treatment, and a biopsy confirmed a diagnosis of ductal carcinoma with multiple lymphatic tumor emboli.
참고문헌 (10)
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