복합부위통증증후군 1형 환자에서 한냉부하 적외선체열촬영의 유용성 평가
Effectiveness of Cold Stress Thermography in the Diagnosis of Complex Regional Pain Syndrome Type 1
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=Effectiveness of Cold Stress Thermography in the Diagnosis ofComplex Regional Pain Syndrome Type 1Eun Jung Park, M.D., Kyung Ream Han, M.D., Yun Jeong Chae, M.D., Won Ho Jeong, M.D., and Chan Kim, M.D.Pain Clinic, Department of Anesthesiology and Pain Medicine, College of Medicine, Ajou University, Suwon, KoreaBackground: Despite the enormous amount of basic research on neuropathic pain, there is the lack of an objective diagnostic test for complex regional pain syndrome (CRPS). The aim of this study was to evaluate the usefulness of cold stress thermography in the diagnosis of CRPS.Methods: The study involved 12 patients with CRPS type 1, according to the IASP criteria, who were compared with 15 normal healthy volunteers. All subjects underwent thermographic examination under baseline conditions at 21oC. A cold stress test (CST; 10oC water for 1 minute) was then applied to both hands below the wrists, immediate, and after 10 and 20 minutes. Results: The temperature asymmetry between the patients with CRPS and the volunteers showed significant discrimination at the baseline and after a 20 minute recovery period from the CST. Among the study subjects having temperature asymmetry of both hands of less than 1oC (8 out of 12 CRPS patients and 14 out of 15 volunteer), 7 (87.5%) of the 8 CRPS patients and 3 (21%) of the 14 volunteers showed a temperature difference of more than 1oC after the 20 minute recovery period. The actual temperature values during the four periods did not discriminate between the patients with CRPS and the volunteers. Conclusions: Thermography, under the CST, could be a more objective test for the diagnosis of CRPS. A temperature asymmetry greater than 1oC during the 20 minute recovery period following CST provides strong diagnostic information about CRPS, with both high sensitivity and specificity. (Korean J Pain 2006; 19: 159 163)
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