복합부위통증증후군 환자에서 삼상 골스캔의 유용성 평가
The Effectiveness of a Three Phase Bone Scan for Making the Diagnosis of Complex Regional Pain Syndrome
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Background: Complex regional pain syndrome (CRPS) is still difficult to diagnose in the field of chronic pain management. CRPS is diagnosed by purely clinical criteria based on the characteristic signs and symptoms, which have to be differentiated from similar pain conditions like posttraumatic neuropathic pain. Until now, there has been a lack of objective diagnostic tools to confirm the diagnosis of CRPS. The aim of this study was to evaluate the usefulness of a three phase bone scan (TBS) for making the diagnosis of CRPS. Methods: A total of 121 patients who had been diagnosed with CRPS were evaluated. All the patients were examined by performing a TBS as a part of the diagnostic work-up. A diffuse increased tracer uptake on the delayed image (phase Ⅲ) was defined as a positive finding for CRPS. Results: Forty-one patients (33.9%) out of 121 showed the positive results on the TBS. The patients with a duration of pain of less than 24 months had a significantly higher positive result (43.4%) on the TBS than did the patients with duration of pain longer than 24 months (12.1%). Conclusions: A TBS could give a better objective result for diagnosing CRPS for patients with a shorter duration of pain and a TBS gives little information for the diagnosis of CRPS in patients with a duration of pain longer than 24 months.
Abstract
Background: Complex regional pain syndrome (CRPS) is still difficult to diagnose in the field of chronic pain management. CRPS is diagnosed by purely clinical criteria based on the characteristic signs and symptoms, which have to be differentiated from similar pain conditions like posttraumatic neuropathic pain. Until now, there has been a lack of objective diagnostic tools to confirm the diagnosis of CRPS. The aim of this study was to evaluate the usefulness of a three phase bone scan (TBS) for making the diagnosis of CRPS. Methods: A total of 121 patients who had been diagnosed with CRPS were evaluated. All the patients were examined by performing a TBS as a part of the diagnostic work-up. A diffuse increased tracer uptake on the delayed image (phase Ⅲ) was defined as a positive finding for CRPS. Results: Forty-one patients (33.9%) out of 121 showed the positive results on the TBS. The patients with a duration of pain of less than 24 months had a significantly higher positive result (43.4%) on the TBS than did the patients with duration of pain longer than 24 months (12.1%). Conclusions: A TBS could give a better objective result for diagnosing CRPS for patients with a shorter duration of pain and a TBS gives little information for the diagnosis of CRPS in patients with a duration of pain longer than 24 months.
참고문헌 (21)
- Galer BS, "IASP diagnostic criteria for complex regional pain syndrome: a preliminary empirical validation study. International Association for the Study of Pain", Clin J Pain, 14, pp.48~54 (1998)
- de Mos M, "The incidence of complex regional pain syndrome: a population-based study", Pain, 129, pp.12~20 (2007)
- Harden RN, "Proposed new diagnostic criteria for complex regional pain syndrome", Pain Med, 8, pp.326~331 (2007)
- Kim YC, "Complex regional pain syndrome. In: Pain medicine. 3rd ed", pp.76~78 (2007), Koonja Publishing Inc
- McMahon SB, "Wall and Melzack's textbook of pain. 5th ed", pp.1011~1020 (2006), Elsevier Churchill Livingstone
- Holder LE, "Reflex sympathetic dystrophy in the foot: clinical and scintigraphic criteria", Radiology, 184, pp.531~535 (1992)
- Kozin F, "Bone scintigraphy in the reflex sympathetic dystrophy syndrome", Radiology, 138, pp.437~443 (1981)
- Davidoff G, "Predictive value of the three-phase technetium bone scan in diagnosis of reflex sympathetic dystrophy syndrome", Arch Phys Med Rehabil, 70, pp.135~137 (1989)
- Allen G, "Epidemiology of complex regional pain syndrome: a retrospective chart review of 134 patients", Pain, 80, pp.539~544 (1999)
- 박상현, "제1형 복합부위 통증증후군의 진단에서 적외선 체열측정과 3상 골스캔의 유용성", The Korean Journal of Pain, 19(1), pp.13~13 (2006), 대한통증학회
- Schürmann M, "Imaging in early posttraumatic complex regional pain syndrome: a comparison of diagnostic methods", Clin J Pain, 23, pp.449~457 (2007)
- Pankaj A, "Diagnosis of post-traumatic complex regional pain syndrome of the hand: current role of sympathetic skin response and three-phase bone scintigraphy", J Orthop Surg, 14, pp.284~290 (2006)
- Werner R, "Factors affecting the sensitivity and specificity of the three-phase technetium bone scan in the diagnosis of reflex sympathetic dystrophy syndrome in the upper extremity", J Hand Surg, 14, pp.520~523 (1989)
- Love C, "Radionuclide bone imaging: an illustrative review", Radiographics, 23, pp.341~358 (2003)
- Sandroni P, "Complex regional pain syndrome type I: incidence and prevalence in Olmsted country, a population-based study", Pain, 103, pp.199~207 (2003)
- Ochoa JL, "Reflex sympathetic dystrophy; a disease of medical understanding", Clin J Pain, 8, pp.363~366 (1992)
- Veldman PH, "Signs and symptoms of reflex sympathetic dystrophy: prospective study of 829 patients", Lancet, 342, pp.1012~1016 (1993)
- Tondeur M, "Interobserver reproducibility in the interpretation of bone scans from patients suspected of having reflex sympathetic dystrophy", Clin Nucl Med, 30, pp.4~10 (2005)
- Sarikaya A, "Technetium-99m sestamibi limb scintigraphy in post- traumatic reflex sympathetic dystrophy: preliminary results", Eur J Nucl Med, 28, pp.1517~1522 (2001)
- Fournier RS, "Reflex sympathetic dystrophy: diagnostic controversies", Semin Nucl Med, 28, pp.116~123 (1998)
- 박정미, "외상 후 복합부위통증증후군 환자에서 시행한 삼상 뼈 스캔의 판독 신뢰도에 관한 연구", Nuclear Medicine and Molecular Imaging, 42(1), pp.44~51 (2008), 대한핵의학회
