Administration of Vitamin C in a Patient with Herpes Zoster - A case report -
0
조회
0
다운로드
6
인용
0
참고문헌
키워드
초록
Herpes zoster as a result of reactivated varicella-zoster virus is characterized by vesicular eruptions on skin and painful neuralgia in the dermatome distribution. Pain during an acute phase of herpes zoster has been associated with a higher risk of developing postherpetic neuralgia. The current therapies for herpes zoster including analgesics and sympathetic nerve block as well as antiviral agents are important to alleviate pain and prevent postherpetic neuralgia. However, in some cases, the pain does not respond well to these treatments. We had a case in which a patient with herpes zoster did not respond to conventional therapy so we attempted to administer intravenous infusion of vitamin C which resulted in an immediate reduction in the pain.
Abstract
Herpes zoster as a result of reactivated varicella-zoster virus is characterized by vesicular eruptions on skin and painful neuralgia in the dermatome distribution. Pain during an acute phase of herpes zoster has been associated with a higher risk of developing postherpetic neuralgia. The current therapies for herpes zoster including analgesics and sympathetic nerve block as well as antiviral agents are important to alleviate pain and prevent postherpetic neuralgia. However, in some cases, the pain does not respond well to these treatments. We had a case in which a patient with herpes zoster did not respond to conventional therapy so we attempted to administer intravenous infusion of vitamin C which resulted in an immediate reduction in the pain.
참고문헌 (19)
- Arvin A, "Aging, immunity, and the varicella-zoster virus", N Engl J Med, 352, pp.2266~2267 (2005)
- Levin MJ, "Prevention strategies for herpes zoster and post-herpetic neuralgia", J Clin Virol, 48(1), pp.S14~S19 (2010)
- Wu CL, "The role of sympathetic nerve blocks in herpes zoster and postherpetic neuralgia", Pain, 87, pp.121~129 (2000)
- Finnerup NB, "The evidence for pharmacological treatment of neuropathic pain", Pain, 150, pp.573~581 (2010)
- Chen JY, "Treatment of postherpetic neuralgia with intravenous administration of vitamin C", Anesth Analg, 103, pp.1616~1617 (2006)
- Chen JY, "Plasma vitamin C is lower in postherpetic neuralgia patients and administration of vitamin C reduces spontaneous pain but not brush-evoked pain", Clin J Pain, 25, pp.562~569 (2009)
- Schencking M, "Intravenous administration of vitamin C in the treatment of herpetic neuralgia: two case reports", Med Sci Monit, 16, pp.CS58~CS61 (2010)
- Drolet M, "The impact of herpes zoster and postherpetic neuralgia on health-related quality of life: a prospective study", CMAJ, 182, pp.1731~1736 (2010)
- Dworkin RH, "Pain and its persistence in herpes zoster", Pain, 67, pp.241~251 (1996)
- Petersen KL, "Natural history of sensory function after herpes zoster", Pain, 150, pp.83~92 (2010)
- Dworkin RH, "Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebo-controlled trial", Neurology, 60, pp.1274~1283 (2003)
- Schorah CJ, "Total vitamin C, ascorbic acid, and dehydroascorbic acid concentrations in plasma of critically ill patients", Am J Clin Nutr, 63, pp.760~765 (1996)
- Besse JL, "Effect of vitamin C on prevention of complex regional pain syndrome type I in foot and ankle surgery", Foot Ankle Surg, 15, pp.179~182 (2009)
- Perez RS, "Evidence based guidelines for complex regional pain syndrome type 1", BMC Neurol, 10, pp.20~ (2010)
- Bruehl S, "An update on the pathophysiology of complex regional pain syndrome", Anesthesiology, 113, pp.713~725 (2010)
- Miclescu A, "Nitric oxide and pain: 'Something old, something new'", Acta Anaesthesiol Scand, 53, pp.1107~1120 (2009)
- Chung JM, "The role of reactive oxygen species (ROS) in persistent pain", Mol Interv, 4, pp.248~250 (2004)
- Rice ME, "Ascorbate regulation and its neuroprotective role in the brain", Trends Neurosci, 23, pp.209~216 (2000)
- Lonnrot K, "The effect of ascorbate and ubiquinone supplementation on plasma and CSF total antioxidant capacity", plasma and CSF total antioxidant capacity. Free Radic Biol Med, 21, pp.211~217 (1996)
