Effects of adjunctive daily phototherapy on chronic periodontitis: a randomized single-blind controlled trial
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Purpose: The purpose of this randomized single-blind controlled trial was to elucidate theclinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling androot planing (SRP) in patients with chronic periodontitis. Methods: The study was conducted from December 2013 to May 2014 at Ewha WomansUniversity Mokdong Hospital, Seoul, Korea. Forty-one patients with mild to moderatechronic periodontitis were randomly divided into two therapeutic groups in a 1:1 ratio:SRP+PT and SRP (control) groups. All participants underwent full-mouth SRP. PT was performedthrice a day for a month by using electric toothbrushes with embedded light-emittingdiodes. Plaque index, gingival index, probing pocket depth (PPD), clinical attachmentlevel (CAL), and bleeding on probing were assessed before (baseline) and four weeks after(follow-up) the treatment. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis,Tannerella forsythia, Treponema denticola, Prevotella intermedia, Fusobacteriumnucleatum, Parvimonas micra, Campylobacter rectus, Eikenella corrodens, Streptococcusmutans, and Streptococcus sobrinus levels were detected by a real-time polymerase chainreaction at the same points in time. Results: The clinical parameters improved in both the groups. At the follow-up assessment,PPD was significantly decreased in the SRP+PT group (P=0.00). Further, PPD and CALshowed significantly greater changes in the SRP+PT group than in the SRP group (PPD,P=0.03; CAL, P=0.04). P. gingivalis and T. forsythia levels decreased in this group, but nosignificant intergroup differences were noted. Conclusions: Adjunctive PT seems to have clinical benefits, but evidence of its antimicrobialeffects is not sufficient. Long-term studies are necessary to develop the most effective PTprotocol and compare the effectiveness of PT with and without exogenous photosensitizers.
Abstract
Purpose: The purpose of this randomized single-blind controlled trial was to elucidate theclinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling androot planing (SRP) in patients with chronic periodontitis. Methods: The study was conducted from December 2013 to May 2014 at Ewha WomansUniversity Mokdong Hospital, Seoul, Korea. Forty-one patients with mild to moderatechronic periodontitis were randomly divided into two therapeutic groups in a 1:1 ratio:SRP+PT and SRP (control) groups. All participants underwent full-mouth SRP. PT was performedthrice a day for a month by using electric toothbrushes with embedded light-emittingdiodes. Plaque index, gingival index, probing pocket depth (PPD), clinical attachmentlevel (CAL), and bleeding on probing were assessed before (baseline) and four weeks after(follow-up) the treatment. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis,Tannerella forsythia, Treponema denticola, Prevotella intermedia, Fusobacteriumnucleatum, Parvimonas micra, Campylobacter rectus, Eikenella corrodens, Streptococcusmutans, and Streptococcus sobrinus levels were detected by a real-time polymerase chainreaction at the same points in time. Results: The clinical parameters improved in both the groups. At the follow-up assessment,PPD was significantly decreased in the SRP+PT group (P=0.00). Further, PPD and CALshowed significantly greater changes in the SRP+PT group than in the SRP group (PPD,P=0.03; CAL, P=0.04). P. gingivalis and T. forsythia levels decreased in this group, but nosignificant intergroup differences were noted. Conclusions: Adjunctive PT seems to have clinical benefits, but evidence of its antimicrobialeffects is not sufficient. Long-term studies are necessary to develop the most effective PTprotocol and compare the effectiveness of PT with and without exogenous photosensitizers.
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